دورية أكاديمية
Factors Associated With Coronary Angiography Performed Within 6 Months of Randomization to the Conservative Strategy in the ISCHEMIA Trial.
| العنوان: | Factors Associated With Coronary Angiography Performed Within 6 Months of Randomization to the Conservative Strategy in the ISCHEMIA Trial. |
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| المؤلفون: | Pracoń R; National Institute of Cardiology, Warsaw, Poland (R.P., W.R.)., Spertus JA; Saint Luke's Mid America Heart Institute, University of Missouri-Kansas City (J.A.S.)., Broderick S; Duke Clinical Research Institute, Durham, NC (S. Broderick, F.W.R.)., Bangalore S; Cardiovascular Clinical Research Center, New York University Grossman School of Medicine (S. Bangalore, J.D.N., H.R.R., J.S.H.)., Rockhold FW; Duke Clinical Research Institute, Durham, NC (S. Broderick, F.W.R.).; Department of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, NC (F.W.R.)., Ruzyllo W; National Institute of Cardiology, Warsaw, Poland (R.P., W.R.)., Demchenko E; Almazov National Medical Research Centre, Saint Petersburg, Russia (E.D.)., Nageh T; Southend University Hospital, United Kingdom (T.N.)., Grossman GB; Moinhos de Vento Hospital, Porto Alegre, Brazil (G.B.G.).; Cardionuclear Clinic, Porto Alegre, Brazil (G.B.G.)., Mavromatis K; Emory University, Atlanta VA Healthcare System, GA (K.M.)., Manjunath CN; Sri Jayadeva Institute of Cardiovascular Sciences and Research, Bengaluru, India (C.N.M.)., Smanio PEP; Instituto Dante Pazzanese de Cardiologia, São Paulo, Brazil (P.E.P.S.)., Stone GW; Icahn School of Medicine at Mount Sinai, New York, NY (G.W.S.)., Mancini GBJ; Center for Cardiovascular Innovation, The University of British Columbia, Vancouver, Canada (G.B.J.M.)., Boden WE; VA New England Healthcare System, Boston University School of Medicine, MA (W.E.B.)., Newman JD; Cardiovascular Clinical Research Center, New York University Grossman School of Medicine (S. Bangalore, J.D.N., H.R.R., J.S.H.)., Reynolds HR; Cardiovascular Clinical Research Center, New York University Grossman School of Medicine (S. Bangalore, J.D.N., H.R.R., J.S.H.)., Hochman JS; Cardiovascular Clinical Research Center, New York University Grossman School of Medicine (S. Bangalore, J.D.N., H.R.R., J.S.H.)., Maron DJ; Department of Medicine, Stanford University, CA (D.J.M.). |
| مؤلفون مشاركون: | ISCHEMIA Research Group |
| المصدر: | Circulation. Cardiovascular interventions [Circ Cardiovasc Interv] 2024 Jun; Vol. 17 (6), pp. e013435. Date of Electronic Publication: 2024 Apr 17. |
| نوع المنشور: | Journal Article; Randomized Controlled Trial; Multicenter Study |
| اللغة: | English |
| بيانات الدورية: | Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 101499602 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1941-7632 (Electronic) Linking ISSN: 19417640 NLM ISO Abbreviation: Circ Cardiovasc Interv Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Hagerstown, MD : Lippincott Williams & Wilkins |
| مواضيع طبية MeSH: | Coronary Angiography* , Computed Tomography Angiography* , Coronary Artery Disease*/diagnostic imaging , Coronary Artery Disease*/therapy , Predictive Value of Tests* , Conservative Treatment*/adverse effects, Humans ; Male ; Female ; Middle Aged ; Aged ; Time Factors ; Treatment Outcome ; Risk Factors ; Risk Assessment ; Chronic Disease |
| مستخلص: | Background: ISCHEMIA (International Study of Comparative Health Effectiveness With Medical and Invasive Approaches) did not find an overall reduction in cardiovascular events with an initial invasive versus conservative management strategy in chronic coronary disease; however, there were conservative strategy participants who underwent invasive coronary angiography early postrandomization (within 6 months). Identifying factors associated with angiography in conservative strategy participants will inform clinical decision-making in patients with chronic coronary disease. Methods: Factors independently associated with angiography performed within 6 months of randomization were identified using Fine and Gray proportional subdistribution hazard models, including demographics, region of randomization, medical history, risk factor control, symptoms, ischemia severity, coronary anatomy based on protocol-mandated coronary computed tomography angiography, and medication use. Results: Among 2591 conservative strategy participants, angiography within 6 months of randomization occurred in 8.7% (4.7% for a suspected primary end point event, 1.6% for persistent symptoms, and 2.6% due to protocol nonadherence) and was associated with the following baseline characteristics: enrollment in Europe versus Asia (hazard ratio [HR], 1.81 [95% CI, 1.14-2.86]), daily and weekly versus no angina (HR, 5.97 [95% CI, 2.78-12.86] and 2.63 [95% CI, 1.51-4.58], respectively), poor to fair versus good to excellent health status (HR, 2.02 [95% CI, 1.23-3.32]) assessed with Seattle Angina Questionnaire, and new/more frequent angina prerandomization (HR, 1.80 [95% CI, 1.34-2.40]). Baseline low-density lipoprotein cholesterol <70 mg/dL was associated with a lower risk of angiography (HR, 0.65 [95% CI, 0.46-0.91) but not baseline ischemia severity nor the presence of multivessel or proximal left anterior descending artery stenosis >70% on coronary computed tomography angiography. Conclusions: Among ISCHEMIA participants randomized to the conservative strategy, angiography within 6 months of randomization was performed in <10% of patients. It was associated with frequent or increasing baseline angina and poor quality of life but not with objective markers of disease severity. Well-controlled baseline low-density lipoprotein cholesterol was associated with a reduced likelihood of angiography. These findings point to the importance of a comprehensive assessment of symptoms and a review of guideline-directed medical therapy goals when deciding the initial treatment strategy for chronic coronary disease. Registration: URL: https://www.clinicaltrials.gov; Unique identifier: NCT01471522. Competing Interests: Disclosures Dr Pracoń reports grants from the National Heart, Lung, and Blood Institute (NHLBI), during the conduct of the study. Dr Spertus reports grants from the NHLBI, during the conduct of the study; personal fees from Bayer, Novartis, AstraZeneca, Amgen, Janssen, and United Healthcare; grants from the American College of Cardiology; and personal fees from Blue Cross Blue Shield of Kansas City, outside the submitted work. In addition, Dr Spertus has a patent Copyright to the Seattle Angina Questionnaire with royalties paid and Equity in Health Outcomes Sciences. Dr Bangalore reports grants from the NHLBI, during the conduct of the study; grants and personal fees from Abbott; and personal fees from Biotronik, Pfizer, Amgen, and Reata outside the submitted work. Dr Rockhold receives research support from the National Institutes of Health, Patient-Centered Outcomes Research Institute (PCORI), BMS, AstraZeneca, American Regent, the Gates Foundation, and Eidos; consulting fees from Janssen, Clover, Doctor Evidence, Resolve, and Intercept; is on the data safety and monitoring boards (DSMBs) for Lilly, AstraZeneca, Merck, Gilead, Novartis, Icosavax, Sanofi, Union Chimique Belge (UCB), Amgen, Biogen, BMS, Pulmocide, Alkermes, and Diurnal; is the nonprofit chairman of the board (unpaid) of the Frontier Science Foundation; and has stock/stock options in GSK, Clover, Athira, Doctor Evidence, DataVant, Spencer Health Solutions, and Adaptic Health. Dr Mavromatis reports grants from the NHLBI; grants from NHLBI (Cardiovascular Inflammation Reduction Trial and GMCSF in PAD-3 trial [Granulocyte-Macrophage Stimulating Factor (GM-CSF) in Peripheral Arterial Disease (GPAD-3)]); grants from CSL Behring, St Jude’s Medical, Medtronic, DalCor Pharmaceuticals, AstraZeneca, Novartis, and Regeneron; and is a member of the American College of Cardiology and the Society of Cardiovascular Angiography and Interventions. Dr Manjunath reports grants from NHLBI during the conduct of the study. Dr Stone reports grants from NHLBI during the conduct of the study; has received speaker honoraria from Pulnovo and Infraredx; has served as a consultant to Valfix, TherOx, Robocath, HeartFlow, Ablative Solutions, Vectorious, Miracor, Neovasc, Abiomed, Ancora, Elucid Bio, Occlutech, CorFlow, Apollo Therapeutics, Impulse Dynamics, Vascular Dynamics, Shockwave, V-Wave, Cardiomech, Gore, and Amgen; and has equity/options from Ancora, Cagent, Applied Therapeutics, Biostar Family of Funds, SpectraWave, Orchestra Biomed, Aria, Cardiac Success, Valfix, and Xenter. Dr Stone’s daughter is an employee at Medtronic. Dr Stone’s employer, Mount Sinai Hospital, receives research support from Abbott, Bioventrix, Cardiovascular Systems, Inc, Phillips, Biosense-Webster, Shockwave, Vascular Dynamics, and V-Wave. Dr Mancini reports grants from NHLBI, during the conduct of the study; grants and personal fees from Amgen, Sanofi, Boehringer Ingelheim, AstraZeneca, Bayer, Janssen, and Novo Nordisk; grants from Novartis; and grants and personal fees from HLS Therapeutics, outside the submitted work. Dr Boden reports grants from NHLBI, during the conduct of the study; grants from Abbvie, Amarin, and Amgen; and personal fees from Amgen, the Cleveland Clinic Clinical Coordinating Center, and Janssen, outside the submitted work. Dr Newman reports grants from NHLBI, during the conduct of the study. Dr Reynolds reports grants from NHLBI, during the conduct of the study, and receives support from Abbott Vascular (donation of optical coherence tomography catheters for an unrelated research study) and Biotelemetry, Inc (donation of telemetry monitors for an unrelated research study). Dr Hochman is a primary investigator for the ISCHEMIA trial (International Study of Comparative Health Effectiveness With Medical and Invasive Approaches) for which, in addition to support by NHLBI grant, devices and medications were provided by Abbott Vascular, Medtronic, Inc, Abbott Laboratories (formerly St. Jude Medical, Inc), Royal Philips NV (formerly Volcano Corporation), Arbor Pharmaceuticals LLC, AstraZeneca Pharmaceuticals LP, Merck Sharp & Dohme Corporation, Omron Healthcare, Inc, Sunovion Pharmaceuticals, Inc, Espero BioPharma, and Amgen, Inc, and financial donations from Arbor Pharmaceuticals LLC and AstraZeneca Pharmaceuticals LP. Dr Hochman is also a primary investigator for the ISCHEMIA-EXTEND trial (The International Study of Comparative Health Effectiveness With Medical and Invasive Approaches [ISCHEMIA] Extended Follow-Up). Dr Maron reports grants from NHLBI, during the conduct of the study. The other authors report no conflicts. |
| References: | N Engl J Med. 2020 Apr 9;382(15):1408-1419. (PMID: 32227753) Circulation. 2023 Jan 3;147(1):8-19. (PMID: 36335918) JAMA Cardiol. 2021 May 1;6(5):593-599. (PMID: 33566062) N Engl J Med. 2020 Apr 9;382(15):1395-1407. (PMID: 32227755) Eur Heart J. 2020 Jan 14;41(3):407-477. (PMID: 31504439) Circ Cardiovasc Qual Outcomes. 2013 Jul;6(4):409-18. (PMID: 23838107) Am Heart J. 2018 Jul;201:124-135. (PMID: 29778671) |
| معلومات مُعتمدة: | UL1 TR001445 United States TR NCATS NIH HHS; U01 HL105462 United States HL NHLBI NIH HHS; U01 HL105561 United States HL NHLBI NIH HHS; U01 HL105907 United States HL NHLBI NIH HHS; U01 HL105565 United States HL NHLBI NIH HHS |
| فهرسة مساهمة: | Investigator: J Doan; J Linefsky; R Lee; R Patel; T Miller; S Yang Cho; S Milbrandt; D Shelstad; S Banerjee; P Kamath; I Tejani; SE Cobos; KJ Quiles; RR Dwyer; RM Donnino; D Espinosa; LM Phillips; M Saric; K Abdul-Nour; A Schley; H Golden; PH Stone; H Osseni; C Wiyarand; P Douglass; H Pomeroy; A Craft; B Harvey; JJ Jang; O Anaya; G Yee; P Goold; S Weitz; S Giovannone; L Pritchard; S Arnold; R Gans; J Henry O'Keefe; P Kennedy; MD Shapiro; S Ganesan; D Schlichting; A Naher; M El-Hajjar; MS Sidhu; SA Fein; WL Stewart; MT Torosoff; KM Salmi; R Lyubarova; S Mookherjee; K Drzymalski; EO McFalls; SA Garcia; SC Bertog; DK Johnson; RA Siddiqui; RR Herrmann; A Ishani; RA Hansen; M Georges Khouri; K Arges; M LeFevre; J Tomfohr; JL Goldberg; K Ann Byrne; T Zappernick; R Goldweit; S Canada; M Kakade; P Mieses; SE Cobos; RR Dwyer; RA Cohen; D Espinosa; B Mirrer; KJ Quiles; V Navarro; M Rantinella; J Rodriguez; O Mancilla; DE Winchester; S Stinson; M Kronenberg; T Weyand; P Rogal; SC Crook; C McFarren; JF Heitner; J Ho; S Khan; M Mohamed; IM Dauber; MR Soltau; DK Rose; RJ Wimmer; KE Siegel; S Derbyshire; C Cannan; M Dixon; G Leonard; S Sudarshan; C Heard; V Gabriel; S Desire; PK Mehta; M McDaniel; F Rashid; S Lerakis; S Asier; A Quyyumi; K Patel; NK Wenger; CM Hedgepeth; J Gillis; H Hurlburt; M Manocchia; A Rosen; S Moore; E Congdon; Z Sahul; G Brandt; N Marchelletta; K Wippler; D Booth; Y Taul; S Leung; J Isaacs; A Abdel-Latif; V Bulkley; H Reda; C Rodgers; K Ziada; S Setty; KE Halverson; C Roraff; J Thorsen; RS Barua; A Ojajuni; O Olurinde; K Surineni; F Hage; B Valaiyapathi; C Caldeira; JE Davies; M Leesar; J Heo; A Iskandrian; F Al Solaiman; S Singh; K Dajani; CM Kartje; M El-Hajjar; P Mesropian; J Sacco; M Rawlins; B McCandless; J Thomson; M Orgera; MS Sidhu; M Colleen Rogge; I Arif; J Bunke; H Kerr; K Unterbrink; J Fannon; C Burman; JF Trejo; MF Dubin; G Fletcher; GE Lane; LM Neeson; PP Parikh; PM Pollak; BP Shapiro; K Landolfo; A Gemignani; S Beaudry; D O'Rourke; JL Meadows; SA Tirado; J Halliday; P Julian; JT Call; SM Lane; JL Stanford; J Hannan; R Bojar; P Arsenault; D Kumar; P Sigel; J Mukai; ET Martin; M Brooks; G Vorobiof; L Douangvila; R Gevorgyan; A Moorman; F Ranjbaran; B Smith; C Ohmart; S Kinlay; RJ Hamburger; TP Rocco; S Ly; DL Bhatt; MC Quinn; K Croce; S Temiyasathit; JA Quin; J Do; J Anumpa; D Tobin; M Zenati; DP Faxon; G Rayos; J Langdon; M Werner Bayer; A Seedhom; A O'Malley; L Sullenberger; E Orvis; G Kumkumian; M Murphy; A Greenberg; M Iraola; SP Sedlis; LC Maranan; RM Donnino; J Lorin; JE Tamis-Holland; A Malinay; R Kornberg; R Leber; S Saba; CP Edillo; MW Lee; DR Small; W Nona; PB Alexander; I Rehman; U Badami; A Ostrander; S Wasmiller; K Marzo; W Drewes; D Patel; IH Robbins; HA Levite; JM White; S Shetty; A Hallam; M Patel; GS Hamroff; BJ Spooner; LM Hollenweger; RW Little; H Little; BD Zimbelman; T Little; CY Lui; NA Eskelson; BR Smith; DP Vezina; LL Khor; JD Abraham; DA Bull; SH McKellar; D Booth; Y Taul; J Kotter; C Rodgers; A Abdel-Latif; J Isaacs; V Bulkley; B Hu; R Kaneshiro; AJ Labovitz; M Berlowitz; BJ Kirby; P Rogal; NN Tran; C McFarren; C Jahrsdorfer; F Matar; C Caldeira; F Rodriguez; R Yunis; I Schnittger; J Patro; WF Fearon; P Deedwania; A Vega; K Reddy; J Sweeny; H Bloise-Adames; S Jimenez; N Saint Vrestil; R Bhandari; C Spizzieri; D Schade; R Yost; CP Hochberg; P Beardsley; D Fine; WD Salerno; J Tancredi; P Arakelian; S Mathus; D O'Neill; R Wyman; J Burkhardt; S Hosino; OA Lubyanaya; JD Salas; A Zarka; M Aguirre; AV Shah; M Dhawan; D Parra; T Tran; T Haldis; C Weick; K Fowler-Lehman; N Spitzer; C Riedberger; C Weick; JA Kohn; SE Cobos; RR Dwyer; D Espinosa; KJ Quiles; S Girotra; C Drum; K Miller-Cox; A Ollinger; O Almousalli; E Capasso-Gulve; A Melanie Loehr; M Mosley; MS Krishnam; S Heydari; JC Milliken; AM Lundeen; PM Patel; E Karanjah; AH Seto; WC Marfori; KT Harley; E Hernandez-Rangel; MA Gibson; P Singh; BJ Allen; R Coram; A Marie Webb; E Fridell; H Wilson; S Thomas; A Kim; RG Schwartz; P Wilmot; W Chen; M El Shahawy; R Stevens; J Stafford; L Black; WB Abernethy; AB Hull; OJ Lim; HC Tucker; NC Putnam; LL Hall; T Cauthren; T Tucker; A Zurick; H Horton; J Orga; TM Meyer; JR White; RG Morford; C Baumann; B Rutkin; V Seeratan; S Bokhari; M Jimenez; SI Sokol; C Schultz; J Meisner; J Russo; I Hamzeh; A Misra; Z Huda; M Wall; A Boan; V Lenges De Rosen; M Alam; MC Turner; CR Hinton; TJ Mulhearn; AP Good; BA Archer; JS Dionne; CA Allardyce; LN Sikora; JH Czerniak; JA Mull; E Ferguson; F Laube; NW Shammas; GA Shammas; L Christensen; H Park; R Chilton; J Hecht; PK Nguyen; D Vo; J Hirsch; M Jezior; J Bindeman; S Salkind; D Espinosa; LA Desimone; PC Gordon; L Felix-Stern; T Crain; J Gomes; C Gordon; R Stenberg; A Mann; T McCreary; RP Pedalino; SE Cobos; RR Dwyer; D Espinosa; KJ Quiles; J Wiesel; SE Cobos; RR Dwyer; D Espinosa; KJ Quiles; GJ Juang; C Gopaul; K Hultberg; T Huk; A Hussain; M Al-Amoodi; Y Zambrano; S Medina Rodriguez; T Milner; D Wohns; A Mulder; S Van Oosterhout; EW Lader; M Meyer; M Mumma; NL Clapp; H Barrentine; L Dharmarajan; JM Jose; SE Cobos; RR Dwyer; D Espinosa; KJ Quiles; J Manchery; JFX McGarvey; V McKinney; L Schwarz; TR Downes; SM Kaczkowski; GJ Luckasen; AJ Jaskowiak; J Klitch; B Cheong; D Dees; S Potluri; P Vasquez; RA Mastouri; JA Breall; EL Hannemann; GE Revtyak; J Mae Foltz; JW Bazeley; D Li; E DeRosa; B Jorgenson; J Riestenberg-Smith; K Giedd; W Old; R Bariciano; F Burt; K Sokhon; J Waldron; M Mayon; D Gopal; US Valeti; G Ann Peichel; J Kobashigawa; B Starks; L Garcia; M Thottam; B Bhargava; A Anand; S Chakanalil Govindan; J Raj; R Gopalan Nair; R Ravindran; VS Rajalekshmi; N Nataraj; N Moorthy; S Nayak; M Mylarappa; S Narayanappa; N Pandit; S Bajaj; R Kumar Nath; V Yadav; G Mishra; SK Dwivedi; R Tewari; VS Narain; M Mishra; S Chandra; S Patel; S Singh; GS Wander; R Tandon; S Ralhan; B Kaur; N Aslam; S Gupta; A Goyal; B Bhargava; C Suvarna; G Karthikeyan; S Ramakrishnan; S Seth; R Yadav; S Singh; A Roy; N Parakh; S Kumar Verma; R Narang; S Mishra; N Naik; G Sharma; S Kumar Choudhary; C Patel; G Gulati; S Sharma; VK Bahl; A Mathew; B Mannekkattukudy Kurian; E Punnoose; M Avdhoot Gadkari; S Rupesh Karwa; S Gadage; S Kolhe; T Umesh Pillay; S Satheesh; RJ Vindhya; P Jain; A Seth; Z Singh Meharwal; A Mathur; A Verma; U Kaul; M Bhatia; A Sachdeva; T Indira Devi; N Jungla; J Christopher; K Manjula Rani; R Menon; M Sowjanya Reddy; N Kumar; K Preethi; A Oomman; RR Sidh; R Mao; T Ramakrishnan; H Solomon; R Francis; S Naik; PP Vamshi; S Parveen Khan; J Christopher; K Preethi; N Kumar; P Grant; S Hande; P Sonawane; R Kachru; A Dubey; K Rawat; A Kumar; S Ganapathi; J K; V Cp; H Sivadasanpillai; M Chacko; B Sasidharan; S Babu; K Tr; J Christopher; S Reddy; P Polamuri; M Rani; U Kaul; P Arambam; B Singh; R Senior; KA Fox; GM Young; K Carruthers; R Senior; A Elghamaz; S Gurunathan; N Karogiannis; GM Young; BN Shah; C Kinsey; RH Trimlett; R Kavalakkat; MB Rubens; J Evans; ED Nicol; I Hassan; TK Mittal; R Hampson; R Andreas Gamma; S Williams; K Holland; K Swan; MA de Belder; B Atkinson; J Thambyrajah; S Kunhunny; JR Davies; SJ Lindsay; C Atkinson; J Kurian; C Krannila; H Jamil; M Vinod; O Raheem; A Hoye; L Chaytor; L Cox; J Morrow; K Rowe; P Donnelly; S Kelly; B Valecka; S Regan; D Turnbull; A Chauhan; C Fleming; A Ghosh; K Gratrix; S Preston; C Barr; A Cartwright; K Alfakih; A Knighton; J Byrne; K Martin; I Webb; P Henriksen; L Flint; J Harrison; P OKane; N Lakeman; A Ljubez; R de Silva; DSG Conway; J Wright; D Exley; AA Sirker; M Andiapen; AJ Richards; SP Hoole; L Wong; FN Witherow; MJ Munro; N Johnston; M Harbinson; M McEvoy; S Walsh; C Brown; H Douglas; M Luckie; T Charles; L Kolakaluri; H Phillips; J Sobolewska; L Morby; K Hallett; C Corbett; L Winstanley; P Jeetley; A Smit; N Patel; T Kotecha; C Travill; S Gent; I Karimullah; N Hussain; M Al-Bustami; D Braganza; F Haines; J Taaffe; R Henderson; J Burton; K Pointon; M Colton; S Naik; R King; T Mathew; A Brown; A Docherty; C Berry; L McCloy; D Collison; K Robb; G Roditi; C Paterson; W Crawford; J Kelly; L McGregor; AJ Moriarty; A Mackin; JD Glover; JP Knight; J Pradhan; G Mikhail; T Bose; DP Francis; V Dzavik; S Goodman; G Gosselin; G Gosselin; A Proietti; M Brousseau; M Corfias; P Blaise; L Harvey; A Diaz; P Rheault; M Barrero; CÉ Gagné; P Alarie; Y Pépin-Dubois; L Arcand; R Costa; I Roy; Y Tung Sia; E Montpetit; C Lemay; A Gisbert; P Gervais; A Rheault; K Drouin; D Carl Phaneuf; C Bergeron; G Gosselin; C Shelley; C Masson; P Garg; S Carr; C Bone; BJW Chow; E Moga; RC Hessian; J Kourzenkova; RS Beanlands; O Walter; RF Davies; KR Bainey; N Hogg; S Welsh; AN Cheema; A Bagai; R Wald; S Goodman; K Kushniriuk; J Joseph Graham; M Hussain; M Peterson; O Bello; CM Chow; B Abramson; A Nazir Cheema; I Syed; M Hussain; K Kushniriuk; J Cha; J Otis; R Otis; AG Howarth; MM Seib; SM Rivest; R Sandonato; G Wong; J Chow; A Starovoytov; N Uchida; N Meadows; A Uxa; N Asif; S Tavares; P Galiwango; B Bozek; S Kassam; M Shier; A Mukherjee; LA Larmand; AJ Ricci; A Janmohamed; B Hart; A Lam; J Marucci; S Tai; S Mehta; S Brons; C Beck; G Wong; K Etherington; T Arumairajah; J Udell; M Aprile; S Karlsson; S Webber; P Généreux; C Mercure; A Hameed; N Aedy; L Daba; F Farquharson; A Siddiqui; A Carlos Carvalho; RD Lopes; W Hueb; M Emy Takiuti; P Cury Rezende; E Eustáquio Ribeiro Silva; A Ciappina Hueb; L Pizzol Caetano; A Schaan de Quadros; R Abdala Karam Kalil; A Peixoto Deiro; J Luiz da Costa Vieira; A Manica Muller; M Antonieta Pereira de Moraes; P Píccaro de Oliveira; B Maria Ascoli; L Bridi; S Zottis Poletti; S Savaris; JV Vitola; RJ Cerci; SS Zier; FR Farias; V Veiga; MM Fernandes; J Antonio Marin-Neto; A Schmidt; M de Oliveira Lima Filho; D Franca da Cunha; R Mendes Oliveira; J Reynaldo Abbud Chierice; CA Polanczyk; GG Rucatti; MV Furtado; F Igansi; LF Smidt; MP Haeffner; A Carlos Carvalho; V Almeida; G Pucci; G Sanchez de Souza; F Lyra; A Rabelo Alves Junior; M Almeida; V Dos Santos; MDA Dracoulakis; NS Oliveira; RGSD Lima; E Figueiredo; B Edilena Paulino Azevedo; P Ricardo Caramori; M Bizzaro Santos; A Germann; V Gomes; R Homem; E Magedanz; R Tumelero; R Laimer; A Tognon; F Dall'Orto; CT Mesquita; RP Santos; AS Colafranseschi; AC Oliveira; LA Carvalho; IC Palazzo; AS Sousa; E Eustáquio Ribeiro da Silva; P Gabriel Melo de Barros E Silva; M Yumi Okada; L de Pádua Silva Baptista; A Paula Batista; M Jamus Rodrigues; A Nogueira Rabaça; M Valério Coimbra de Resende; J Francisco Saraiva; L Miranda Trama; T Silva; C Thais de Souza Ormundo; C Vicente; C Costantini; C Pinheiro; D Komar; H Szwed; M Demkow; C Kepka; A Teresinska; O Walesiak; K Kryczka; K Malinowska; J Henzel; M Solecki; E Kaczmarska; T Mazurek; J Maksym; K Wojtera; A Fojt; E Szczerba; J Drozdz; B Czarniak; M Frach; K Szymczyk; I Niedzwiecka; S Sobczak; T Ciurus; P Jakubowski; M Misztal-Teodorczyk; D Teodorczyk; M Swiderek; A Fratczak; E Wojtala; M Szkopiak; P Lebioda; M Wlodarczyk; A Plachcinska; J Kusmierek; M Miller; H Marciniak; K Wojtczak-Soska; K Łuczak; T Tarchalski; A Cichocka-Radwan; H Szwed; J Karwowski; G Anna Szulczyk; A Witkowski; K Kukuła; M Celińska-Spodar; J Zalewska; G Gajos; K Bury; P Pruszczyk; A Łabyk; M Roik; A Szramowska; O Zdończyk; K Łoboz-Grudzień; J Jaroch; L Sokalski; B Brzezińska; M Lesiak; M Łanocha; KW Reczuch; A Kolodziej; Z Kalarus; A Swiatkowski; M Szulik; WJ Musial; M Marcinkiewicz-Siemion; O Bockeria; L Bockeria; O Bockeria; K Petrosyan; Z Kudzoeva; T Trifonova; N Aripova; AM Chernyavskiy; IA Naryshkin; EI Kretov; A Kuleshova; IO Grazhdankin; D Malaev; LL Bershtein; SA Sayganov; I Subbotina; AM Kuzmina-Krutetskaya; V Gumerova; EV Zbyshevskaya; NO Katamadze; OB Nikolaeva; PS Kozlov; VY Kozulin; EI Lubinskaya; J Luis Lopez-Sendon; A Castro; J Lopez-Sendon; V Fernández-Figares; A Castro; E Refoyo Salicio; G Guzman; G Galeote; S Valbuena; J Peteiro; M Dolores Martínez-Ruíz; R Pérez-Fernández; M Blanco-Calvo; JJ Cuenca-Castillo; E Alonso-Álvarez; X Flores-Ríos; P García-González; Ó Prada-Delgado; G Barge-Caballero; J Ramon Gonzalez Juanatey; J Seijas Amigo; M Souto Bayarri; V Pubull Nuñez; R Ocaranza Sanchez; B Cid Alvarez; C Peña Gil; A Martinez Monzonis; A Sionis; A Fernández Martínez; M Vila Perales; J Maria Padró; A Serra Peñaranda; J García Picart; A Ginel Iglesias; X Garcia-Moll Marimon; G Pons Lladó; F Carreras Costa; V Miro; B Igual; JL Diez; P Calvillo; FM Ortuño; M Valdés Chávarri; M Quintana Giner; A Tello Montolliu; AI Romero Aniorte; E Pinar Bermudez; JM Rivera Caravaca; G De La Morena; M Gracida Blancas; O Cañavate; S Guerrero; S Riera; J Enrique Castillo Luena; J Enrique Castillo Luena; M Lasala; F Fernandez-Aviles; M Lorenzo; O Sobrino; A Vazquez; L Jiang; J Chen; H Dong; P He; C Xia; J Yang; Q Zhong; Y Wu; Y Tian; D Li; Y Ma; X Li; Y Yang; X Ma; Z Yu; Q Zhao; Z Ji; C Li; L Zhang; Y Zhao; B Zhu; X Yang; M Chen; H Chi; Y Wang; J Zhang; W Lin; R Jing; J Liu; H Zeng; Q Zhou; C Xu; Z Li; J Li; L Xiong; X Fu; D Gao; D Jiang; R Leng; X Wang; Q Yuan; L Zhang; B Yang; Z Bai; J Li; J Qi; F Wang; H Wang; B Yang; Z Yue; Z Zhang; S Wang; Y Dong; J Mao; B Zhang; G Cheng; X Li; X Yao; N Zhong; N Zhou; Y Zhao; Y Huang; P Zhou; X Fang; W Su; Q Zeng; Y Kunwu; Y Peng; X Su; X Su; C Wang; Y Zhao; Q Li; Y Geng; Y Wang; SP Nie; JY Fan; ST Feng; X Wang; Y Yan; HM Zhang; Q Yu; L Chi; F Liu; J Wang; H Chen; J Jiang; H Li; J Wang; Y Han; L Xu; S Zhang; Z Liu; Z Liu; G Chen; R Hu; AP Maggioni; G Piero Perna; F Pietrucci; M Marini; G Gabrielli; S Provasoli; A Di Donato; E Verna; L Monti; B Nardi; A Di Chiara; F Pezzetta; A Mortara; V Casali; M Galvani; C Attanasio; F Ottani; M Sicuro; G Leone; F Pisano; C Bare; P Calabro; F Fimiani; T Formisano; G Tarantini; A Barioli; U Cucchini; F Ramani; A Luigi Andres; E Racca; F Rolfo; C Goletto; C Briguori; F De Micco; R Amati; S Di Marco; W Vergoni; M Tricoli; A Russo; M Villella; R Fanelli; H Douglas White; C Alsweiler; KK Poh; P Chai; T Lau; JP Loh; EL Tay; K Teoh; SV Tan; LL Teo; WC Sia; CC Ong; AW Leong; RC Wong; PH Loh; T Kofidis; W Xian Chan; K Hui Chan; D Foo; L Hai Yan; J Loh Kwok Kong; C Min Er; F Haider Jafary; T Chua; N Ismail; M Tun Kyaw; D Yip; R Doerr; R Doerr; J Stumpf; D Grahl; K Matschke; F Guenther; G Simonis; K Bonin; CT Kadalie; U Sechtem; I Wenzelburger; P Ong; S Gruensfelder; P Christian Schulze; B Goebel; K Lenk; G Nickenig; JM Sinning; M Weber; N Werner; I Marthe Lang; K Huber; H Schuchlenz; G Steinmaurer; S Weikl; I Marthe Lang; MP Winter; T Andric; K Huber; M Tscharre; G Jakl-Kotauschek; C Wegmayr; B Jäger; F Egger; M Keltai; A Vertes; J Sebo; Z Davidovits; L Matics; A Varga; G Ágoston; G Fontos; G Dekany; B Merkely; A Bartykowszki; P Maurovich-Horvat; G Kerecsen; A Jakal; S Hinic; J Djokic; M Zdravkovic; V Mudrenovic; B Crnokrak; BD Beleslin; NN Boskovic; AD Djordjevic-Dikic; MT Petrovic; VL Giga; MR Dobric; JJ Stepanovic; ZZ Markovic; AS Mladenovic; N Cemerlic-Adjic; L Velicki; S Kamenica; L Pupic; G Davidović; SM Simović; R Vučić; MN Dekleva; MS Martinovic; G Stevanovic; G Stankovic; M Dobric; S Apostolovic; SS Martinovic; D Stanojevic; J Escobedo; R Jesús-Pérez; B Juarez; R Baleón-Espinosa; AS Campos-Santaolalla; E Durán-Cortés; JM Flores-Palacios; A García-Rincón; M Jiménez-Santos; JV Peñafiel; JA Ortega-Ramírez; A Valdespino-Estrada; EA Rosas; MF Canales Brassetti; DA Vences Anaya; MP García; IE Carvajal Juarez; MM Rovalo; ED Morales Rodríguez; JB Selvanayagam; J Rankin; D Murphy; JB Selvanayagam; S Lee; MX Joseph; P Thomas; ST Thambar; MD Chaplin; SC Boer; JF Beltrame; JK Stansborough; M Black; GS Hillis; MM Bonner; KF Ireland; C Venn-Edmonds; PG Steg; H Abergel; JM Juliard; C Thobois; CHL Pasteur; C Thuaire; E Tachot; T Dutoiu; C Laure; C Vassaliere; PG Steg; H Abergel; JM Juliard; A Fuentes; MS Slama; L Eliahou; C Cedex; R El Mahmoud; O Dubourg; P Michaud; E Nicollet; S Hadjih; CE Cedex; P Goube; P Brito; G Barone-Rochette; G Barone-Rochette; A Furber; C Cornet; L Bière; J Rautureau; A Juceviciene; I Kalibataite-Rutkauskiene; L Keinaite; A Laucevicius; M Laukyte; J Celutkiene; G Mikolaitiene; A Smigelskaite; I Tamasauskiene; A Urboniene; E Kedhi; I Klinieken; J Timmer; I Bouwhuis; R Hermanides; L Nijmeijer; E Kaplan; RK Riezebos; P Samadi; JJM Schoep; EV Dongen; EM Janzen; SR Niehe; H Suryapranata; S Ahoud; SV Vugt; R Ramos; H Santa Marta; D Cacela; A Santana; A Fiarresga; L Sousa; H Marques; L Patricio; M Selas; L Bernanrdes; F Silva; P Rio; C Freixo; R Carvalho; R Ferreira; T Silva; I Rodrigues; P Modas; G Portugal; J Fragata; FJ Pinto; IZ Cabrita; MN Menezes; A Rocha; GC Lopes; FP Figueiras; AG Almeida; A Coelho; P CanVas Silva; M Capinha; A Nobre; MI Caetano; AR Francisco; S Silva; N Ferreira; VN de Gaia; RL Lopes; R Diaz; L Guzman; V Tinnirello; JC Figal; M Nicolás Mungo; CA Buenos Aires; O Méndiz; C Cortés; RR Favaloro; C Alvarez; M Garcia; B Blanca; J Courtis; V Godoy; G Zeballos; L Schiavi; MV Actis; M Rubio; G Scaro; HD White; C Alsweiler; GP Devlin; L Low; R Fisher; J Scales; K Abercrombie; RAH Stewart; L Howell; HD White; C Patten; J Benatar; S Kedev; IP Mitevska; ES Kostovska; H Pejkov; C Held; C Held; K Eggers; G Frostfelt; C Björklund; N Johnston; M Andreasson; M Olsowka; M Essermark; A Åkerblom; I Soveri; J Aspberg; L Persson; R Beyar; T Sharir; E Nikolsky; T Sharir; O Harel; D Elian; A Kerner; M Bentzvi; S Massalha; L Helmer; S Kohsaka; K Fukuda; I Ueda; S Kohsaka; J Fujita; S Yasuda; A Furukawa; K Hirase; T Nagai; F Otsuka; S Nishimura; S Nakano; FV de Werf; K Goetschalckx; K Goetschalckx; V Robesyn; FV de Werf; K Claes; HD White; C Alsweiler; CL Hung; YH Yang; CH Yun; CJ Hou; JY Kuo; HI Yeh; TC Hung; JY Li; CY Chien; CT Tsai; CC Liu; FC Yu; YH Lin; WR Lan; CH Yen; JP Tsai; KT Sung; M Ntsekhe; S Pandie; C Philander Nee Talliard; CA Viljoen; N Mtana; M De Andrade; AP Maggioni; T Moccetti; A Anesini; MG Rossi; S Maspoli; M Mombelli; M Abdelhamid; A Talaat; A Adel; A Kamal; H Mahrous; SE Kaffas; HE Fishawy; C Pop; M Claudia; BA Popescu; C Ginghina; M Rosca; D Deleanu; CC Beladan; VA Iliescu; MH Al-Mallah; S Zahrani; A Aljzeeri; H Najm; A Alghamdi; WE Mogrovejo Ramos; MA Monsalve Davila; HD White; C Alsweiler; S Kuanprasert; C Mai; A Prommintikul; W Nawarawong; S Khwakhong; S Woragidpoonpol; A Chaiyasri; T Tepsuwan; W Mekara; N Taksaudom; S Kulthawong; C Rimsukcharoenchai; A Amaritakomol; J Euathrongchit; Y Wannasopha; S Yamwong; P Panpunuan; P Sritara; S Aramcharoen; K Meemuk; HD White; C Alsweiler; A Khairuddin; NS Mokhtar; HA Hadi; NA Basri; SA Yahaya; I Yusnida; H Hashim; R Harrington; D Williams; KP Alexander; J Berger; R Harrington; D Mark; SM O'Brien; Y Rosenberg; LJ Shaw; C Ballantyne; D Berman; R Beyar; B Bhargava; C Buller; A Tony Carvalho; BR Chaitman; R Diaz; R Doerr; V Dzavik; S Goodman; G Gosselin; R Hachamovitch; C Hamm; C Held; M Helm; K Huber; L Jiang; M Keltai; S Kohsaka; I Lang; R Lopes; J Lopez-Sendon; A Maggioni; CN Bairey Merz; J Min; E Peterson; MH Picard; J Selvanayagam; R Senior; T Sharir; G Steg; H Szwed; FV de Werf; W Weintraub; H White; D Williams; C Ballantyne; K Calfas; BR Chaitman; MA Champagne; M Davidson; J Fleg; PA McCullough; P Stone; P Menasche; M Davidson; S Fremes; R Guyton; M Mack; F Mohr; A Rao; J Sabik; O Shapira; D Taggart; J Tatoulis; D Williams; J Blankenship; S Brener; C Buller; A Colombo; B Bruyne; P Généreux; R Harrington; D Kereiakes; T Lefevre; J Moses; BR Chaitman; KP Alexander; K Mahaffey; H White; BR Chaitman; S Cruz-Flores; N Danchin; E Feen; MJ Garcia; P Hauptman; AA Laddu; E Passamani; IL Pina; M Simoons; H Skali; K Thygesen; D Waters; KP Alexander; P Endsley; G Esposito; J Kanters; J Pownall; D Stournaras; LJ Shaw; D Berman; M Friedrich; R Hachamovitch; R Kwong; J Min; D Oliver; MH Picard; F Harrell; J Blume; K Lee; SM O'Brien; J Berger; C Held; I Kullo; B McManus; K Newby; D Mark; D Cohen; W Weintraub; CNB Merz; R Bugiardini; J Celutkiene; J Escobedo; A Hoye; R Lyubarova; D Mattina; J Peteiro; KP Alexander; J Berger; R Harrington; SM O'Brien; Y Rosenberg; D Mark; D Mark; LJ Shaw; D Berman; BR Chaitman; J Fleg; R Kwong; MH Picard; R Senior; J Min; J Leipsic; Z Ali; D Williams; J Fleg; J Berger; BR Chaitman; KP Alexander; KP Alexander; J Fleg; R Mathew; SM O'Brien; M Sidhu; L Friedman; J Anderson; J Berg; D DeMets; CM Gibson; G Lamas; N Deming; J Himmelfarb; P Ouyang; P Woodard; F Harrell; S Nwosu; Y Rosenberg; J Fleg; R Kirby; N Jeffries; J Berger; M Sidhu; JE Denaro; S Mavromichalis; K Chan; G Cobb; A Contreras; D Cukali; S Ferket; A Gabriel; A Hansen; A Roberts; M Chang; S Islam; G Wayser; S Yakubov; M Yee; C Callison; I Hogan; A Qelaj; C Pirro; KV Loo; B Wisniewski; M Gilsenan; B Lang; S Mohamed; S Esquenazi-Karonika; P Mathews; A Naumova; J Lyo; V Setang; M Xavier; SM O'Brien; KP Alexander; DB Mark; K Anstrom; K Baloch; J Blount; P Cowper; L Davidson-Ray; L Drew; T Harding; JD Knight; DM Liu; B O'Neal; T Redick; P Jones; K Nugent; GJ Wang; LJ Shaw; L Phillips; A Goyal; H Hetrick; D Oliver; D Berman; SW Hayes; JD Friedman; RJ Gerlach; M Hyun; R Miranda-Peats; P Slomka; L Thomson; RY Kwong; M Friedrich; FP Mongeon; S Michael; MH Picard; J Hung; M Scherrer-Crosbie; X Zeng; BR Chaitman; J Eckstein; B Guruge; M Streif; Z Ali; P Genereux; MA Alfonso; MP Corral; JJ Garcia; J Horst; I Jankovic; M Konigstein; MB Lustre; Y Peralta; R Sanchez; J Min; R Arsanjani; M Budoff; K Elmore; M Gomez; C Hague; N Hindoyan; J Leipsic; R Nakanishi; MB Srichai-Parsia; E Yeoh; T Youn; AP Maggioni; F Bianchini; M Ceseri; A Lorimer; M Magnoni; F Orso; L Sarti; M Tricoli; A Carvalho; R Lopes; LM Barbosa; TB Duarte; TC Soares; J Aveiro Morata; P Carvalho; N Carvalho Maffei; F Egydio; A Kawakami; J Oliveira; ER Piloto; J Pozzibon; S Goodman; D Camara; N Mowafy; C Spindler; L Jiang; H Dai; F Feng; J Li; L Li; J Liu; Q Xie; H Zhang; J Zhang; L Zhang; L Zhang; N Zhang; H Zhong; R Diaz; C Escobar; ME Martin; A Pascual; J Lopez-Sendon; P Moraga; V Hernandez; A Castro; M Posada; S Fernandez; JLN Villanueva; R Selgas; G Steg; H Abergel; JM Juliard; H White; C Alsweiler; FV de Werf; K Claes; K Goetschalckx; A Luyten; V Robesyn; JB Selvanayagam; D Murphy; A Ahmed; R Bhatt; N Chadha; V Kumar; S Lubna; P Naik; S Pandey; K Ramasamy; M Saleem; P Sharma; H Siddaram Keywords: angiography; coronary disease; ischemia; mortality; quality of life |
| سلسلة جزيئية: | ClinicalTrials.gov NCT01471522 |
| تواريخ الأحداث: | Date Created: 20240417 Date Completed: 20240618 Latest Revision: 20240623 |
| رمز التحديث: | 20240623 |
| مُعرف محوري في PubMed: | PMC11187765 |
| DOI: | 10.1161/CIRCINTERVENTIONS.123.013435 |
| PMID: | 38629312 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1941-7632 |
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| DOI: | 10.1161/CIRCINTERVENTIONS.123.013435 |