دورية أكاديمية
أعرض في EDS

Development and validation of an analytical methodology based on solvent microextraction and UHPLC-MS/MS for determining bisphenols in honeys from different botanical origins.

التفاصيل البيبلوغرافية
العنوان: Development and validation of an analytical methodology based on solvent microextraction and UHPLC-MS/MS for determining bisphenols in honeys from different botanical origins.
المؤلفون: Martín-Gómez B; Analytical Chemistry Group (TESEA), I. U. CINQUIMA, Faculty of Sciences, University of Valladolid, 47011 Valladolid, Spain., Valverde S; Analytical Chemistry Group (TESEA), I. U. CINQUIMA, Faculty of Sciences, University of Valladolid, 47011 Valladolid, Spain., Bernal J; Analytical Chemistry Group (TESEA), I. U. CINQUIMA, Faculty of Sciences, University of Valladolid, 47011 Valladolid, Spain., Ares AM; Analytical Chemistry Group (TESEA), I. U. CINQUIMA, Faculty of Sciences, University of Valladolid, 47011 Valladolid, Spain. Electronic address: ana.maria.ares@uva.es.
المصدر: Food chemistry [Food Chem] 2024 Aug 30; Vol. 450, pp. 139358. Date of Electronic Publication: 2024 Apr 15.
نوع المنشور: Journal Article; Evaluation Study; Validation Study
اللغة: English
بيانات الدورية: Publisher: Elsevier Applied Science Publishers Country of Publication: England NLM ID: 7702639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7072 (Electronic) Linking ISSN: 03088146 NLM ISO Abbreviation: Food Chem Subsets: MEDLINE
أسماء مطبوعة: Publication: Barking : Elsevier Applied Science Publishers
Original Publication: Barking, Eng., Applied Science Publishers.
مواضيع طبية MeSH: Phenols*/analysis , Phenols*/isolation & purification , Tandem Mass Spectrometry* , Honey*/analysis , Benzhydryl Compounds*/analysis , Benzhydryl Compounds*/isolation & purification , Benzhydryl Compounds*/chemistry , Liquid Phase Microextraction*/methods , Food Contamination*/analysis, Chromatography, High Pressure Liquid
مستخلص: A new analytical methodology was proposed to determine fourteen bisphenols in honeys from different botanical origins using ultra-high performance liquid chromatography-tandem mass spectrometry. A fast, efficient, environmentally-friendly and simple sample treatment (recoveries between 81% and 116%; matrix effect <20% for all studied compounds except for bisphenol E, F and S) was proposed, which involved a solvent microextraction with acetone and a small volume/amount of 1-hexanol. Chromatographic analysis (< 15 min) was performed in a Kinetex EVO C 18 column under gradient elution mode. The method was validated in terms of selectivity, limits of detection (0.2-1.5 μg/kg) and quantification (0.5-4.7 μg/kg), linearity, matrix effect, trueness, and precision (relative standard deviation <17%). Finally, thirty honey samples were analyzed, revealing the presence of residues of nine bisphenols in some of them. However, quantification was possible only in two cases for bisphenol A, with a concentration of approximately 13 μg/kg.
Competing Interests: Declaration of competing interest The authors of this manuscript declare no conflict of interest.
(Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.)
فهرسة مساهمة: Keywords: Bisphenols; Food safety; Green analytical chemistry; Honey; Method validation; Sample treatment; UHPLC-MS/MS
المشرفين على المادة: 0 (Phenols)
0 (Benzhydryl Compounds)
MLT3645I99 (bisphenol A)
تواريخ الأحداث: Date Created: 20240417 Date Completed: 20240525 Latest Revision: 20240525
رمز التحديث: 20240525
DOI: 10.1016/j.foodchem.2024.139358
PMID: 38631201
قاعدة البيانات: MEDLINE
الوصف
تدمد:1873-7072
DOI:10.1016/j.foodchem.2024.139358