دورية أكاديمية
The Incidence of Pulmonary Embolism in Hospitalized Non-ICU Patients with COVID-19 during the First Wave: A Multicenter Retrospective Cohort Study in the Netherlands.
| العنوان: | The Incidence of Pulmonary Embolism in Hospitalized Non-ICU Patients with COVID-19 during the First Wave: A Multicenter Retrospective Cohort Study in the Netherlands. |
|---|---|
| المؤلفون: | Maas AFG; VieCuri Medical Center, Department of Internal Medicine, Venlo, The Netherlands., Wyers C; VieCuri Medical Center, Department of Internal Medicine, Venlo, The Netherlands., Dielis A; VieCuri Medical Center, Department of Internal Medicine, Venlo, The Netherlands., Barten DG; VieCuri Medical Center, Department of Emergency Medicine, Venlo, The Netherlands., van Kampen VEM; VieCuri Medical Center, Department of Pulmonology, Venlo, The Netherlands., van der Krieken TE; VieCuri Medical Center, Department of Radiology, Venlo, The Netherlands., de Kruif M; Zuyderland Hospital, Department of Pulmonology, Heerlen, The Netherlands., Simsek S; Northwest Clinics, Department of Internal Medicine, Alkmaar, The Netherlands.; Department of Internal Medicine/Endocrinology, Amsterdam University Medical Centers, Amsterdam, The Netherlands., Spaetgens B; Department of Internal Medicine, Division of General Internal Medicine, Section Geriatric Medicine, Maastricht University Medical Center and Cardiovascular Research Institute Maastricht (CARIM), Maastricht, The Netherlands., van Haaps T; Amsterdam University Medical Center, Department of Vascular Medicine, Amsterdam, The Netherlands., Appelman B; Center for Experimental and Molecular Medicine, Amsterdam UMC Location University of Amsterdam, Department(s), Amsterdam, The Netherlands., Gritters NC; Treant Zorggroep, Department of Intensive Care, Emmen, The Netherlands., Doornbos S; Treant Zorggroep, Department of Intensive Care, Emmen, The Netherlands., Moeniralam HS; St Antonius Hospital, Department of Internal Medicine, Nieuwegein, The Netherlands., Noordzij PG; St Antonius Hospital, Department of Intensive Care, Nieuwegein, The Netherlands., Reidinga A; Department of Intensive Care, Martini Ziekenhuis, Groningen, The Netherlands., Douma RA; Flevo Hospital, Department of Internal Medicine, Almere, The Netherlands., Nossent EJ; Department of Pulmonary Medicine, Free University Amsterdam, Cardiovascular Sciences Research Institute, Amsterdam, The Netherlands., Beudel M; Department of Neurology, Amsterdam Neuroscience Institute, Amsterdam, The Netherlands., Elbers P; Department of Intensive Care Medicine, Laboratory for Critical Care Computational Intelligence, Amsterdam Institute for Infection and Immunity, Vrije Universiteit, Amsterdam, The Netherlands., Middeldorp S; Department of Internal Medicine, Division of General Internal Medicine, Section Geriatric Medicine, Maastricht University Medical Center and Cardiovascular Research Institute Maastricht (CARIM), Maastricht, The Netherlands., van Es N; Department of Internal Medicine, Division of General Internal Medicine, Section Geriatric Medicine, Maastricht University Medical Center and Cardiovascular Research Institute Maastricht (CARIM), Maastricht, The Netherlands., van den Bergh JPW; VieCuri Medical Center, Department of Internal Medicine, Venlo, The Netherlands.; Maastricht University, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht, The Netherlands., van Osch FHM; Maastricht University, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht, The Netherlands.; VieCuri Medical Center, Department of Clinical Epidemiology, Venlo, The Netherlands. |
| المصدر: | Journal of vascular research [J Vasc Res] 2024; Vol. 61 (3), pp. 142-150. Date of Electronic Publication: 2024 Apr 17. |
| نوع المنشور: | Journal Article; Multicenter Study; News |
| اللغة: | English |
| بيانات الدورية: | Publisher: S. Karger Country of Publication: Switzerland NLM ID: 9206092 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1423-0135 (Electronic) Linking ISSN: 10181172 NLM ISO Abbreviation: J Vasc Res Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Basel ; New York : S. Karger, c1992- |
| مواضيع طبية MeSH: | COVID-19*/epidemiology , COVID-19*/diagnosis , COVID-19*/complications , Pulmonary Embolism*/epidemiology , Pulmonary Embolism*/diagnostic imaging , Pulmonary Embolism*/diagnosis, Humans ; Netherlands/epidemiology ; Retrospective Studies ; Male ; Female ; Aged ; Middle Aged ; Incidence ; Risk Factors ; Aged, 80 and over ; Hospitalization ; Time Factors ; SARS-CoV-2 ; Computed Tomography Angiography |
| مستخلص: | Introduction: During the first COVID-19 outbreak in 2020 in the Netherlands, the incidence of pulmonary embolism (PE) appeared to be high in COVID-19 patients admitted to the intensive care unit (ICU). This study was performed to evaluate the incidence of PE during hospital stay in COVID-19 patients not admitted to the ICU. Methods: Data were retrospectively collected from 8 hospitals in the Netherlands. Patients admitted between February 27, 2020, and July 31, 2020, were included. Data extracted comprised clinical characteristics, medication use, first onset of COVID-19-related symptoms, admission date due to COVID-19, and date of PE diagnosis. Only polymerase chain reaction (PCR)-positive patients were included. All PEs were diagnosed with computed tomography pulmonary angiography (CTPA). Results: Data from 1,852 patients who were admitted to the hospital ward were collected. Forty patients (2.2%) were diagnosed with PE within 28 days following hospital admission. The median time to PE since admission was 4.5 days (IQR 0.0-9.0). In all 40 patients, PE was diagnosed within the first 2 weeks after hospital admission and for 22 (55%) patients within 2 weeks after onset of symptoms. Patient characteristics, pre-existing comorbidities, anticoagulant use, and laboratory parameters at admission were not related to the development of PE. Conclusion: In this retrospective multicenter cohort study of 1,852 COVID-19 patients only admitted to the non-ICU wards, the incidence of CTPA-confirmed PE was 2.2% during the first 4 weeks after onset of symptoms and occurred exclusively within 2 weeks after hospital admission. (© 2024 The Author(s). Published by S. Karger AG, Basel.) |
| References: | Thromb Res. 2020 Sep;193:166-169. (PMID: 32707275) Clin Appl Thromb Hemost. 2021 Jan-Dec;27:1076029621996471. (PMID: 33689493) Thromb Res. 2020 Dec;196:486-490. (PMID: 33091701) Thromb Res. 2021 Nov;207:150-157. (PMID: 34649175) Thromb Res. 2020 Jul;191:9-14. (PMID: 32353746) Vascul Pharmacol. 2021 Aug;139:106882. (PMID: 34087481) Int J Antimicrob Agents. 2020 Sep;56(3):106078. (PMID: 32629115) J Microbiol Immunol Infect. 2021 Feb;54(1):37-45. (PMID: 33500211) Ann Intern Med. 2022 Jan;175(1):29-35. (PMID: 34807722) JAMA. 2020 Aug 25;324(8):782-793. (PMID: 32648899) N Engl J Med. 2020 Apr 30;382(18):1708-1720. (PMID: 32109013) J Thromb Haemost. 2010 Nov;8(11):2450-7. (PMID: 20738765) Lancet. 2020 Mar 28;395(10229):1054-1062. (PMID: 32171076) Eur Heart J. 2020 Jul 1;41(32):3058-3068. (PMID: 32656565) J Thromb Haemost. 2020 Jun;18(6):1421-1424. (PMID: 32271988) PLoS One. 2020 Dec 10;15(12):e0242958. (PMID: 33301459) Int J Surg. 2014 Dec;12(12):1500-24. (PMID: 25046751) Br J Radiol. 2021 Jul 01;94(1123):20210264. (PMID: 34106780) BMJ Open. 2021 Jul 19;11(7):e047347. (PMID: 34281922) Virol J. 2021 Jan 9;18(1):13. (PMID: 33422083) Eur Heart J. 2021 Aug 31;42(33):3127-3142. (PMID: 34164664) Thromb Res. 2020 Dec;196:322-324. (PMID: 32977131) |
| فهرسة مساهمة: | Keywords: COVID-19; Epidemiology; Hospital ward; Pulmonary embolism; Vascular research |
| تواريخ الأحداث: | Date Created: 20240417 Date Completed: 20240603 Latest Revision: 20240717 |
| رمز التحديث: | 20240717 |
| مُعرف محوري في PubMed: | PMC11151976 |
| DOI: | 10.1159/000538312 |
| PMID: | 38631294 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1423-0135 |
|---|---|
| DOI: | 10.1159/000538312 |