دورية أكاديمية

The Clinical Relevance of the Infiltrating Immune Cell Composition in Kidney Transplant Rejection.

التفاصيل البيبلوغرافية
العنوان: The Clinical Relevance of the Infiltrating Immune Cell Composition in Kidney Transplant Rejection.
المؤلفون: Vaulet T; Department of Microbiology, Immunology and Transplantation, Nephrology and Kidney Transplantation Research Group, KU Leuven, Leuven, Belgium., Callemeyn J; Department of Microbiology, Immunology and Transplantation, Nephrology and Kidney Transplantation Research Group, KU Leuven, Leuven, Belgium.; Department of Nephrology and Kidney Transplantation, University Hospitals Leuven, Leuven, Belgium., Lamarthée B; Department of Microbiology, Immunology and Transplantation, Nephrology and Kidney Transplantation Research Group, KU Leuven, Leuven, Belgium.; EFS, INSERM, UMR RIGHT, Université de Franche-Comté, Besançon, France., Antoranz A; Department of Imaging and Pathology, Translational Cell and Tissue Research, KU Leuven, Leuven, Belgium., Debyser T; Department of Microbiology, Immunology and Transplantation, Nephrology and Kidney Transplantation Research Group, KU Leuven, Leuven, Belgium., Koshy P; Department of Imaging and Pathology, Translational Cell and Tissue Research, KU Leuven, Leuven, Belgium., Anglicheau D; Department of Nephrology and Kidney Transplantation, Necker-Enfants Malades Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.; Inserm U1151, Necker Enfants-Malades Institute, Université Paris Cité, Paris, France., Colpaert J; Department of Microbiology, Immunology and Transplantation, Nephrology and Kidney Transplantation Research Group, KU Leuven, Leuven, Belgium., Gwinner W; Department of Nephrology, Hannover Medical School, Hannover, Germany., Halloran PF; Division of Nephrology and Transplant Immunology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada., Kuypers D; Department of Microbiology, Immunology and Transplantation, Nephrology and Kidney Transplantation Research Group, KU Leuven, Leuven, Belgium.; Department of Nephrology and Kidney Transplantation, University Hospitals Leuven, Leuven, Belgium., Tinel C; Department of Microbiology, Immunology and Transplantation, Nephrology and Kidney Transplantation Research Group, KU Leuven, Leuven, Belgium.; EFS, INSERM, UMR RIGHT, Université de Franche-Comté, Besançon, France.; Department of Nephrology and Kidney Transplantation, Dijon University Hospital, Dijon, France., Van Craenenbroeck A; Department of Microbiology, Immunology and Transplantation, Nephrology and Kidney Transplantation Research Group, KU Leuven, Leuven, Belgium.; Department of Nephrology and Kidney Transplantation, University Hospitals Leuven, Leuven, Belgium., Van Loon E; Department of Microbiology, Immunology and Transplantation, Nephrology and Kidney Transplantation Research Group, KU Leuven, Leuven, Belgium.; Department of Nephrology and Kidney Transplantation, University Hospitals Leuven, Leuven, Belgium., Marquet P; Department of Pharmacology and Transplantation, Inserm U1248, Limoges University Hospital, University of Limoges, Limoges, France., Bosisio F; Department of Imaging and Pathology, Translational Cell and Tissue Research, KU Leuven, Leuven, Belgium., Naesens M; Department of Microbiology, Immunology and Transplantation, Nephrology and Kidney Transplantation Research Group, KU Leuven, Leuven, Belgium.; Department of Nephrology and Kidney Transplantation, University Hospitals Leuven, Leuven, Belgium.
المصدر: Journal of the American Society of Nephrology : JASN [J Am Soc Nephrol] 2024 Jul 01; Vol. 35 (7), pp. 886-900. Date of Electronic Publication: 2024 Apr 19.
نوع المنشور: Journal Article; Editorial
اللغة: English
بيانات الدورية: Publisher: Wolters Kluwer Health, on behalf of the American Society of Nephrology Country of Publication: United States NLM ID: 9013836 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1533-3450 (Electronic) Linking ISSN: 10466673 NLM ISO Abbreviation: J Am Soc Nephrol Subsets: MEDLINE
أسماء مطبوعة: Publication: 2023- : Hagerstown, MD : Wolters Kluwer Health, on behalf of the American Society of Nephrology
Original Publication: Baltimore, MD : Williams & Wilkins, c1990-
مواضيع طبية MeSH: Kidney Transplantation* , Graft Rejection*/immunology, Humans ; Clinical Relevance
References: Loupy A, Mengel M, Haas M. Thirty years of the International Banff Classification for Allograft Pathology: the past, present, and future of kidney transplant diagnostics. Kidney Int. 2022;101(4):678–691. doi: 10.1016/j.kint.2021.11.028. (PMID: 10.1016/j.kint.2021.11.028)
Roufosse C, Simmonds N, Clahsen-van Groningen M, et al. A 2018 reference guide to the Banff classification of renal allograft pathology. Transplantation. 2018;102(11):1795–1814. doi: 10.1097/TP.0000000000002366. (PMID: 10.1097/TP.0000000000002366)
Naesens M, Roufosse C, Colvin RB, et al. The Banff 2022 kidney meeting report: Re-appraisal of microvascular inflammation and the role of biopsy-based transcript diagnostics. SSRN Electron J. 2023. doi: 10.2139/ssrn.4447700 . https://papers.ssrn.com/abstract=4447700 . (PMID: 10.2139/ssrn.4447700)
Roufosse C, Naesens M, Colvin RB, et al. The Banff 2022 kidney meeting work plan: data-driven refinement of the Banff classification for renal allografts. SSRN Electron J. 2023. doi: 10.2139/ssrn.4444233 . https://papers.ssrn.com/abstract=4444233 . (PMID: 10.2139/ssrn.4444233)
Halloran PF, Famulski KS, Reeve J. Molecular assessment of disease states in kidney transplant biopsy samples. Nat Rev Nephrol. 2016;12(9):534–548. doi: 10.1038/nrneph.2016.85. (PMID: 10.1038/nrneph.2016.85)
Callemeyn J, Lamarthée B, Koenig A, Koshy P, Thaunat O, Naesens M. Allorecognition and the spectrum of kidney transplant rejection. Kidney Int. 2022;101(4):692–710. doi: 10.1016/j.kint.2021.11.029. (PMID: 10.1016/j.kint.2021.11.029)
Calvani J, Terada M, Lesaffre C, et al. In situ multiplex immunofluorescence analysis of the inflammatory burden in kidney allograft rejection: a new tool to characterize the alloimmune response. Am J Transplant. 2020;20(4):942–953. doi: 10.1111/ajt.15699. (PMID: 10.1111/ajt.15699)
Sicard A, Meas-Yedid V, Rabeyrin M, et al. Computer-assisted topological analysis of renal allograft inflammation adds to risk evaluation at diagnosis of humoral rejection. Kidney Int. 2017;92(1):214–226. doi: 10.1016/j.kint.2017.01.011. (PMID: 10.1016/j.kint.2017.01.011)
Yazdani S, Callemeyn J, Gazut S, et al. Natural killer cell infiltration is discriminative for antibody-mediated rejection and predicts outcome after kidney transplantation. Kidney Int. 2019;95(1):188–198. doi: 10.1016/j.kint.2018.08.027. (PMID: 10.1016/j.kint.2018.08.027)
Lamarthée B, Callemeyn J, Van Herck Y, et al. Transcriptional and spatial profiling of the kidney allograft unravels a central role for FcyRIII+ innate immune cells in rejection. Nat Commun. 2023;14(1):4359. doi: 10.1038/s41467-023-39859-7. (PMID: 10.1038/s41467-023-39859-7)
Halloran PF, Madill-Thomsen KS, Reeve J. The molecular phenotype of kidney transplants: insights from the MMDx project. Transplantation. 2024;108(1):45–71. doi: 10.1097/TP.0000000000004624. (PMID: 10.1097/TP.0000000000004624)
Newman AM, Steen CB, Liu CL, et al. Determining cell type abundance and expression from bulk tissues with digital cytometry. Nat Biotechnol. 2019;37(7):773–782. doi: 10.1038/s41587-019-0114-2. (PMID: 10.1038/s41587-019-0114-2)
Barrett T, Wilhite SE, Ledoux P, et al. NCBI GEO: archive for functional genomics data sets–update. Nucleic Acids Res. 2013;41(Database issue):D991–D995. doi: 10.1093/nar/gks1193. (PMID: 10.1093/nar/gks1193)
Callemeyn J, Lerut E, de Loor H, et al. Transcriptional changes in kidney allografts with histology of antibody-mediated rejection without anti-HLA donor-specific antibodies. J Am Soc Nephrol. 2020;31(9):2168–2183. doi: 10.1681/ASN.2020030306. (PMID: 10.1681/ASN.2020030306)
Reeve J, Sellarés J, Mengel M, et al. Molecular diagnosis of T cell-mediated rejection in human kidney transplant biopsies. Am J Transplant. 2013;13(3):645–655. doi: 10.1111/ajt.12079. (PMID: 10.1111/ajt.12079)
Einecke G, Reeve J, Sis B, et al. A molecular classifier for predicting future graft loss in late kidney transplant biopsies. J Clin Invest. 2010;120(6):1862–1872. doi: 10.1172/JCI41789. (PMID: 10.1172/JCI41789)
Bolognesi MM, Manzoni M, Scalia CR, et al. Multiplex staining by sequential immunostaining and antibody removal on routine tissue sections. J Histochem Cytochem. 2017;65(8):431–444. doi: 10.1369/0022155417719419. (PMID: 10.1369/0022155417719419)
Vaulet T, Divard G, Thaunat O, et al. Data-driven derivation and validation of novel phenotypes for acute kidney transplant rejection using semi-supervised clustering. J Am Soc Nephrol. 2021;32(5):1084–1096. doi: 10.1681/ASN.2020101418. (PMID: 10.1681/ASN.2020101418)
Van Calster B, Van Belle V, Vergouwe Y, Timmerman D, Van Huffel S, Steyerberg EW. Extending the c-statistic to nominal polytomous outcomes: the Polytomous Discrimination Index. Stat Med. 2012;31(23):2610–2626. doi: 10.1002/sim.5321. (PMID: 10.1002/sim.5321)
Efron B, Tibshirani RJ. An Introduction to the Bootstrap. CRC Press; 1994.
Coemans M, Verbeke G, Döhler B, Süsal C, Naesens M. Bias by censoring for competing events in survival analysis. BMJ. 2022;378:e071349. doi: 10.1136/bmj-2022-071349. (PMID: 10.1136/bmj-2022-071349)
Aguado-Domínguez E, Cabrera-Pérez R, Suarez-Benjumea A, Abad-Molina C, Núñez-Roldán A, Aguilera I. Computer-Assisted definition of the inflammatory infiltrates in patients with different categories of Banff kidney allograft rejection. Front Immunol. 2019;10:2605. doi: 10.3389/fimmu.2019.02605. (PMID: 10.3389/fimmu.2019.02605)
Sablik KA, Jordanova ES, Pocorni N, Clahsen-van Groningen MC, Betjes MGH. Immune cell infiltrate in chronic-active antibody-mediated rejection. Front Immunol. 2019;10:3106. doi: 10.3389/fimmu.2019.03106. (PMID: 10.3389/fimmu.2019.03106)
Hasegawa J, Honda K, Omoto K, et al. Clinical and pathological features of plasma cell-rich acute rejection after kidney transplantation. Transplantation. 2018;102(5):853–859. doi: 10.1097/TP.0000000000002041. (PMID: 10.1097/TP.0000000000002041)
Koenig A, Chen CC, Marçais A, et al. Missing self triggers NK cell-mediated chronic vascular rejection of solid organ transplants. Nat Commun. 2019;10(1):5350. doi: 10.1038/s41467-019-13113-5. (PMID: 10.1038/s41467-019-13113-5)
Callemeyn J, Senev A, Coemans M, et al. Missing self–induced microvascular rejection of kidney allografts: a population-based study. J Am Soc Nephrol. 2021;32(8):2070–2082. doi: 10.1681/ASN.2020111558. (PMID: 10.1681/ASN.2020111558)
Halloran PF, Madill-Thomsen KS, Pon S, et al. Molecular diagnosis of ABMR with or without donor-specific antibody in kidney transplant biopsies: differences in timing and intensity but similar mechanisms and outcomes. Am J Transplant. 2022;22(8):1976–1991. doi: 10.1111/ajt.17092. (PMID: 10.1111/ajt.17092)
Hamada S, Dubois V, Koenig A, Thaunat O. Allograft recognition by recipient’s natural killer cells: molecular mechanisms and role in transplant rejection. HLA. 2021;98(3):191–199. doi: 10.1111/tan.14332. (PMID: 10.1111/tan.14332)
Dai H, Friday AJ, Abou-Daya KI, et al. Donor SIRPα polymorphism modulates the innate immune response to allogeneic grafts. Sci Immunol. 2017;2(12):eaam6202. doi: 10.1126/sciimmunol.aam6202. (PMID: 10.1126/sciimmunol.aam6202)
Al-Moussawy M, Abdelsamed HA, Lakkis FG. Immunoglobulin-like receptors and the generation of innate immune memory. Immunogenetics. 2022;74(1):179–195. doi: 10.1007/s00251-021-01240-7. (PMID: 10.1007/s00251-021-01240-7)
Tambur AR, Bestard O, Campbell P, et al. Sensitization in transplantation: assessment of risk 2022 working group meeting report. Am J Transplant. 2023;23(1):133–149. doi: 10.1016/j.ajt.2022.11.009. (PMID: 10.1016/j.ajt.2022.11.009)
Senev A, Ray B, Lerut E, et al. The pre-transplant non-HLA antibody burden associates with the development of histology of antibody-mediated rejection after kidney transplantation. Front Immunol. 2022;13:809059. doi: 10.3389/fimmu.2022.809059. (PMID: 10.3389/fimmu.2022.809059)
Yap M, Boeffard F, Clave E, et al. Expansion of highly differentiated cytotoxic terminally differentiated effector memory CD8+ T cells in a subset of clinically stable kidney transplant recipients: a potential marker for late graft dysfunction. J Am Soc Nephrol. 2014;25(8):1856–1868. doi: 10.1681/ASN.2013080848. (PMID: 10.1681/ASN.2013080848)
Jacquemont L, Tilly G, Yap M, et al. Terminally differentiated effector memory CD8+ T cells identify kidney transplant recipients at high risk of graft failure. J Am Soc Nephrol. 2020;31(4):876–891. doi: 10.1681/ASN.2019080847. (PMID: 10.1681/ASN.2019080847)
Doan Ngoc TM, Tilly G, Danger R, et al. Effector memory–expressing CD45RA (TEMRA) CD8+ T cells from kidney transplant recipients exhibit enhanced purinergic P2X4 receptor–dependent proinflammatory and migratory responses. J Am Soc Nephrol. 2022;33(12):2211–2231. doi: 10.1681/ASN.2022030286. (PMID: 10.1681/ASN.2022030286)
Néel A, Bucchia M, Néel M, et al. Dampening of CD8+ T cell response by B cell depletion therapy in antineutrophil cytoplasmic antibody–associated vasculitis. Arthritis Rheumatol. 2019;71(4):641–650. doi: 10.1002/art.40766. (PMID: 10.1002/art.40766)
Tasaki S, Suzuki K, Nishikawa A, et al. Multiomic disease signatures converge to cytotoxic CD8 T cells in primary Sjögren’s syndrome. Ann Rheum Dis. 2017;76(8):1458–1466. doi: 10.1136/annrheumdis-2016-210788. (PMID: 10.1136/annrheumdis-2016-210788)
Georg P, Astaburuaga-García R, Bonaguro L, et al. Complement activation induces excessive T cell cytotoxicity in severe COVID-19. Cell. 2022;185(3):493–512.e25. doi: 10.1016/j.cell.2021.12.040. (PMID: 10.1016/j.cell.2021.12.040)
Hu M, Wang C, Zhang GY, et al. Infiltrating Foxp3+ regulatory T cells from spontaneously tolerant kidney allografts demonstrate donor-specific tolerance. Am J Transplant. 2013;13(11):2819–2830. doi: 10.1111/ajt.12445. (PMID: 10.1111/ajt.12445)
Cippà PE, Liu J, Sun B, Kumar S, Naesens M, McMahon AP. A late B lymphocyte action in dysfunctional tissue repair following kidney injury and transplantation. Nat Commun. 2019;10(1):1157. doi: 10.1038/s41467-019-09092-2. (PMID: 10.1038/s41467-019-09092-2)
Einecke G, Reeve J, Mengel M, et al. Expression of B cell and immunoglobulin transcripts is a feature of inflammation in late allografts. Am J Transplant. 2008;8(7):1434–1443. doi: 10.1111/j.1600-6143.2008.02232.x. (PMID: 10.1111/j.1600-6143.2008.02232.x)
معلومات مُعتمدة: 305499 FP7 Health; 1016 ROCKET, JTC2-29 Fonds Wetenschappelijk Onderzoek; G087620N Fonds Wetenschappelijk Onderzoek; 1196119N Fonds Wetenschappelijk Onderzoek; 1143919N Fonds Wetenschappelijk Onderzoek; 1S93918N Fonds Wetenschappelijk Onderzoek; 1844019N, 1842919N Fonds Wetenschappelijk Onderzoek; DOS0060162/00 Bpifrance; FC0013440 European Regional Development Fund of the Region Bourgogne Franche-Comté; ANR-22-CE18-0011-01 Agence Nationale de la Recherche; FC0013440 European Regional Development Fund of the Region Bourgogne Franche-Comté
سلسلة جزيئية: ClinicalTrials.gov NCT02832661
تواريخ الأحداث: Date Created: 20240419 Date Completed: 20240701 Latest Revision: 20240711
رمز التحديث: 20240711
مُعرف محوري في PubMed: PMC11230711
DOI: 10.1681/ASN.0000000000000350
PMID: 38640017
قاعدة البيانات: MEDLINE
الوصف
تدمد:1533-3450
DOI:10.1681/ASN.0000000000000350