دورية أكاديمية
أعرض في EDS

Spectral changes in skin blood flow during pressure manipulations or sympathetic stimulation.

التفاصيل البيبلوغرافية
العنوان: Spectral changes in skin blood flow during pressure manipulations or sympathetic stimulation.
المؤلفون: Lima NS; Integrative Physiology Laboratory, University of Illinois at Chicago, Chicago, Illinois, USA., Tzen YT; Integrative Physiology Laboratory, University of Illinois at Chicago, Chicago, Illinois, USA.; University of Texas Southwestern Medical Center, Dallas, Texas, USA., Clifford PS; Integrative Physiology Laboratory, University of Illinois at Chicago, Chicago, Illinois, USA.
المصدر: Experimental physiology [Exp Physiol] 2024 Jun; Vol. 109 (6), pp. 892-898. Date of Electronic Publication: 2024 Apr 20.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 9002940 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-445X (Electronic) Linking ISSN: 09580670 NLM ISO Abbreviation: Exp Physiol Subsets: MEDLINE
أسماء مطبوعة: Publication: Cambridge, Eng : Wiley-Blackwell
Original Publication: Cambridge ; New York, NY, USA : Published for the Physiological Society by Cambridge University Press, c1990-
مواضيع طبية MeSH: Skin*/blood supply , Laser-Doppler Flowmetry*/methods , Regional Blood Flow*/physiology , Sympathetic Nervous System*/physiology, Humans ; Female ; Male ; Adult ; Young Adult ; Forearm/blood supply ; Cold Temperature ; Pressure ; Anesthetics, Local/pharmacology ; Anesthetics, Local/administration & dosage ; Blood Pressure/physiology
مستخلص: Skin blood flow is commonly determined by laser Doppler flowmetry (LDF). It has been suggested that pathophysiological conditions can be assessed by analysis of specific frequency domains of the LDF signals. We tested whether physiological stimuli that activate myogenic and neurogenic mechanisms would affect relevant portions of the laser Doppler spectrum. LDF sensors were placed on the right forearm of 14 healthy volunteers for myogenic (six females) and 13 for neurogenic challenge (five females). Myogenic responses were tested by positioning the arm ∼50° above/below heart level. Neurogenic responses were tested by immersing the left hand into an ice slurry with and without topical application of local anaesthetic. Short-time Fourier analyses were computed over the range of 0.06 to 0.15 Hz for myogenic and 0.02 to 0.06 Hz for neurogenic. No significant differences in spectral density were observed (P = 0.40) in the myogenic range with arm above (7 ± 54 × 10 -4  dB) and below heart (7 ± 14 × 10 -4  dB). Neurogenic spectral density showed no significant increase from baseline to cold pressor test (0.0017 ± 0.0013 and 0.0038 ± 0.0039 dB; P = 0.087, effect size 0.47). After application of anaesthetic, neurogenic spectral density was unchanged between the baseline and cold pressor test (0.0014 ± 0.0025 and 0.0006 ± 0.0005 dB; P = 0.173). These results suggest that changes in the myogenic and neurogenic spectral density of LDF signals did not fully reflect the skin vascular function activated by pressure manipulation and sympathetic stimulation. Therefore, LDF myogenic and neurogenic spectral density data should be interpreted with caution.
(© 2024 The Authors. Experimental Physiology published by John Wiley & Sons Ltd on behalf of The Physiological Society.)
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فهرسة مساهمة: Keywords: myogenic; neurogenic; short‐time Fourier transformation; spectral analysis
المشرفين على المادة: 0 (Anesthetics, Local)
تواريخ الأحداث: Date Created: 20240420 Date Completed: 20240531 Latest Revision: 20240603
رمز التحديث: 20240603
مُعرف محوري في PubMed: PMC11140173
DOI: 10.1113/EP091706
PMID: 38642069
قاعدة البيانات: MEDLINE
الوصف
تدمد:1469-445X
DOI:10.1113/EP091706