دورية أكاديمية
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Higher serum carotenoid concentrations were associated with the lower risk of cancer-related death: Evidence from the National Health and Nutrition Examination Survey.

التفاصيل البيبلوغرافية
العنوان: Higher serum carotenoid concentrations were associated with the lower risk of cancer-related death: Evidence from the National Health and Nutrition Examination Survey.
المؤلفون: Zhang C; Department of Oncology, The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou 450008, PR China., Li K; Department of Oncology, The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou 450008, PR China., Xu SN; Department of Oncology, The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou 450008, PR China., Zhang JK; Department of Gastrointestinal Surgery, The Fourth Affiliated Hospital of China Medical University, Shenyang 110032, PR China., Ma MH; Department of Gastrointestinal Surgery, Maoming People's Hospital, Maoming 525000, PR China., Liu Y; Department of Oncology, The Affiliated Cancer Hospital of Zhengzhou University & Henan Cancer Hospital, Zhengzhou 450008, PR China. Electronic address: zlyyliuying1664@zzu.edu.cn.
المصدر: Nutrition research (New York, N.Y.) [Nutr Res] 2024 Jun; Vol. 126, pp. 88-98. Date of Electronic Publication: 2024 Mar 30.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8303331 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0739 (Electronic) Linking ISSN: 02715317 NLM ISO Abbreviation: Nutr Res Subsets: MEDLINE
أسماء مطبوعة: Publication: <2004- > : Tarrytown, NY : Elsevier Science
Original Publication: New York : Pergamon Press, c1981-
مواضيع طبية MeSH: Carotenoids*/blood , Neoplasms*/mortality , Neoplasms*/blood , Nutrition Surveys*, Humans ; Female ; Male ; Middle Aged ; Adult ; Beta-Cryptoxanthin/blood ; Aged ; Risk Factors ; Lycopene/blood ; United States/epidemiology ; Young Adult ; beta Carotene/blood
مستخلص: The study focuses on the association between serum carotenoids and cancer-related death. Using data from the National Health and Nutrition Examination Survey (2001-2006 and 2017-2018), the study encompasses 10,277 participants older than age 20 years, with recorded baseline characteristics and serum carotenoid concentrations (including α-carotene, trans-β-carotene, cis-β-carotene, β-cryptoxanthin, trans-lycopene, and lutein/zeaxanthin). We hypothesized that serum carotenoid concentrations were negatively associated with cancer-related death. The weighted chi-square analyses indicate significant negative correlations between higher serum concentrations of α-carotene, β-cryptoxanthin, trans-lycopene, and total carotenoids, and the risk of cancer-related deaths. Using weighted Cox regression analysis, this study confirms that α-carotene, β-cryptoxanthin, trans-lycopene, and total carotenoids, as continuous or categorical variables, are inversely related to cancer mortality (P < .0001). Furthermore, considering competitive risk events, lower concentrations of serum β-cryptoxanthin (Fine-Gray P = 1.12e-04), trans-lycopene (P = 5.68e-14), and total carotenoids (P = .03) are associated with an increased risk of cancer-related deaths. The research reveals a crucial inverse relationship between serum carotenoid concentrations and cancer-related death.
Competing Interests: Author Declarations The authors declare no competing interest.
(Copyright © 2024 Elsevier Inc. All rights reserved.)
فهرسة مساهمة: Keywords: Cancer-related death; Carotenoids; α-carotene; β-carotene; β-cryptoxanthin
المشرفين على المادة: 36-88-4 (Carotenoids)
0 (Beta-Cryptoxanthin)
45XWE1Z69V (alpha-carotene)
SB0N2N0WV6 (Lycopene)
01YAE03M7J (beta Carotene)
تواريخ الأحداث: Date Created: 20240420 Date Completed: 20240614 Latest Revision: 20240614
رمز التحديث: 20240615
DOI: 10.1016/j.nutres.2024.03.012
PMID: 38642420
قاعدة البيانات: MEDLINE
الوصف
تدمد:1879-0739
DOI:10.1016/j.nutres.2024.03.012