دورية أكاديمية
Delays in presentation, diagnosis, and treatment in Sudanese women with breast cancer: a cross-sectional study.
| العنوان: | Delays in presentation, diagnosis, and treatment in Sudanese women with breast cancer: a cross-sectional study. |
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| المؤلفون: | Alfadul ESA; Faculty of Medicine, University of Khartoum, Khartoum, Sudan.; Station of Medical Essentials (SOME) Institution, Khartoum, Sudan., Tebaig B; Faculty of Medicine, University of Khartoum, Khartoum, Sudan., Alrawa SS; Faculty of Medicine, University of Khartoum, Khartoum, Sudan., Elgadi AT; Faculty of Medicine, University of Khartoum, Khartoum, Sudan., Margani EEMA; Station of Medical Essentials (SOME) Institution, Khartoum, Sudan.; Faculty of Medicine, University of Sinnar, Sinnar, Sudan., Adam MEB; Station of Medical Essentials (SOME) Institution, Khartoum, Sudan.; Faculty of Medicine, Nahda College, Khartoum, Sudan., Mohamoud MSA; Station of Medical Essentials (SOME) Institution, Khartoum, Sudan.; Faculty of Medicine, Almughtaribeen University, Khartoum, Sudan., Elhassan SAM; Station of Medical Essentials (SOME) Institution, Khartoum, Sudan.; Faculty of Medicine, Omdurman Islamic University, Khartoum, Sudan., Elhassan MMA; Department of Oncology, National Cancer Institute, University of Gezira, Wad Madani, Sudan. |
| المصدر: | The oncologist [Oncologist] 2024 Jun 03; Vol. 29 (6), pp. e771-e778. |
| نوع المنشور: | Journal Article; Multicenter Study |
| اللغة: | English |
| بيانات الدورية: | Publisher: Oxford University Press Country of Publication: England NLM ID: 9607837 Publication Model: Print Cited Medium: Internet ISSN: 1549-490X (Electronic) Linking ISSN: 10837159 NLM ISO Abbreviation: Oncologist Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2022- : Oxford : Oxford University Press Original Publication: Dayton, Ohio : AlphaMed Press, c1996- |
| مواضيع طبية MeSH: | Breast Neoplasms*/therapy , Breast Neoplasms*/diagnosis , Breast Neoplasms*/psychology , Breast Neoplasms*/pathology , Delayed Diagnosis*/statistics & numerical data , Time-to-Treatment*/statistics & numerical data, Humans ; Female ; Cross-Sectional Studies ; Middle Aged ; Sudan/epidemiology ; Adult ; Aged |
| مستخلص: | Background: The poor prognosis of breast cancer in Sudan could be due to delayed treatment and diagnosis at an advanced stage. Our study aimed to assess the extent of delays from onset of symptoms to treatment in Sudanese women with breast cancer, as well as identify factors contributing to these delays. Materials and Methods: We conducted a multi-center cross sectional study between March and April 2023. Data were collected from the medical records and interviews with women with breast cancer in the two main oncology centers in Sudan. Linear regression was used to identify the predictors of delayed presentation. Results: We interviewed 601 women with breast cancer. The majority of women (50.1%) were diagnosed at locally advanced or metastatic disease. The median interval from the onset of symptoms to receiving oncologic treatment was 221 days (IQR = 92, 496). The longest delay was the presentation delay 61 (31 244) days. The median duration for diagnosis delay and treatment delay was 21 (10.57) days and 27 (10.64) days, respectively. Predictors of early presentation included, being young (β = -5.3; 95% CI = 0.06 to 10), married (β = -264; 95% CI = -427 to -101), divorced (β = -306; 95% CI = -549 to -63), or widowed (β = -320; 95% CI = --543 to -97), urban residence (β = -107; 95% CI = -213 to -2.3), and seeking traditional healer (β = -204; 95% CI = -383 to -26). Conclusion: Most Sudanese women with breast cancer experience significant patient delays, often presenting at advanced stages. Factors like being single, older, and living in rural areas contribute to these delays. Increasing breast cancer education, improving healthcare access and addressing sociodemographic barriers can potentially expedite diagnosis and improve outcomes. (© The Author(s) 2024. Published by Oxford University Press.) |
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| فهرسة مساهمة: | Keywords: Africa; breast cancer; diagnosis and treatment interval; early detection; low- and middle-income countries; predictors of delay |
| تواريخ الأحداث: | Date Created: 20240420 Date Completed: 20240603 Latest Revision: 20240815 |
| رمز التحديث: | 20240815 |
| مُعرف محوري في PubMed: | PMC11144982 |
| DOI: | 10.1093/oncolo/oyae066 |
| PMID: | 38642908 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1549-490X |
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| DOI: | 10.1093/oncolo/oyae066 |