دورية أكاديمية
Tricuspid annular plane systolic excursion over systolic pulmonary artery pressure prognostic value for in-hospital adverse events in patients hospitalized for acute coronary syndrome.
| العنوان: | Tricuspid annular plane systolic excursion over systolic pulmonary artery pressure prognostic value for in-hospital adverse events in patients hospitalized for acute coronary syndrome. |
|---|---|
| المؤلفون: | Fauvel C; Cardiology Department, FHU CARNAVAL, Rouen University Hospital, Rouen, France.; INSERM EnVI U1096, Rouen University Hospital, Rouen, France., Dillinger JG; Department of Cardiology, Université de Paris Cité, Hôpital Lariboisière, Assistance Publique-Hôpitaux de Paris, Inserm U-942, 2 rue Ambroise Paré, 75010 Paris, France., Bouleti C; Clinical Investigation Center (INSERM 1204), Cardiology Department, University Hospital of Poitiers, 86000 Poitiers, France., Trimaille A; Department of Cardiovascular Medicine, Nouvel Hôpital Civil, Strasbourg University Hospital, 67000 Strasbourg, France., Tron C; Cardiology Department, FHU CARNAVAL, Rouen University Hospital, Rouen, France., Chaussade AS; Clinique A Paré, Neuilly/Seine, Département de Cardiologie, 92200 Neuilly-sur-Seine, France., Thuaire C; Service de Cardiologie, Centre Hospitalier de Chartres, 28630 Le Coudray, France., Delmas C; Intensive Cardiac Care Unit, Rangueil University Hospital, Toulouse, France., Boccara A; Department of Cardiology, Andre Gregoire Hospital, 93100 Montreuil, France., Roule V; Department of Cardiology, Caen University Hospital, Caen, France., Millischer D; Service de Cardiologie, Hôpital MONTFERMEIL, 93370 Montfermeil, France., Thevenet E; Department of Cardiology, University Hospital of Martinique, 97261 Fort-de-France, France., Meune C; Department of Cardiology, Hôpital Avicenne, Assistance Publique-Hôpitaux de Paris, Paris, France., Stevenard M; Service de cardiologie et médecine aéronautique, Hôpital d'Instruction des Armées Percy, 101 avenue Henri Barbusse, 92140 Clamart, France., Charbonnel C; Service de Cardiologie, Hôpital Mignot, Versailles, France., Maitre Ballesteros L; Service de Cardiologie, CHU Grenoble-Alpes, 38700 La Tronche, France., Pommier T; Department of Cardiology, University Hospital, Dijon, France., El Ouahidi A; Department of Cardiology, University Hospital of Brest, 29609 Brest Cedex, France., Swedsky F; Service de Cardiologie, Hôpital Henri Duffaut, 84902 Avignon, France., Martinez D; Department of Cardiology, Nîmes University Hospital, Montpellier University, Nîmes, France., Hauguel-Moreau M; Service de Cardiologie, Hôpital Ambroise Pare, AP-HP, Boulogne Billancourt, France., Schurtz G; Department of Cardiology, University Hospital of Lille, 59000 Lille, France., Coisne A; Department of Cardiology, University Hospital of Lille, 59000 Lille, France., Dupasquier V; Department of Cardiology, CHU Montpellier, 34295 Montpellier, France., Bochaton T; Intensive Cardiological Care Division, Louis Pradel Hospital, Hospices Civils de Lyon, Bron, France., Gerbaud E; Cardiology Intensive Care Unit and Interventional Cardiology, Hôpital Cardiologique du Haut-Lévêque, 33604 Pessac, France.; Bordeaux Cardio-Thoracic Research Centre, U1045, Bordeaux University, 33076 Bordeaux, France., Puymirat E; Department of Cardiology, Hôpital Européen Georges Pompidou (HEGP), 75015 Paris, France., Henry P; Department of Cardiology, Université de Paris Cité, Hôpital Lariboisière, Assistance Publique-Hôpitaux de Paris, Inserm U-942, 2 rue Ambroise Paré, 75010 Paris, France., Pezel T; Department of Cardiology, Université de Paris Cité, Hôpital Lariboisière, Assistance Publique-Hôpitaux de Paris, Inserm U-942, 2 rue Ambroise Paré, 75010 Paris, France. |
| مؤلفون مشاركون: | ADDICT-ICCU Investigators |
| المصدر: | European heart journal. Cardiovascular Imaging [Eur Heart J Cardiovasc Imaging] 2024 Aug 26; Vol. 25 (9), pp. 1244-1254. |
| نوع المنشور: | Journal Article; Multicenter Study |
| اللغة: | English |
| بيانات الدورية: | Publisher: Oxford University Press Country of Publication: England NLM ID: 101573788 Publication Model: Print Cited Medium: Internet ISSN: 2047-2412 (Electronic) Linking ISSN: 20472404 NLM ISO Abbreviation: Eur Heart J Cardiovasc Imaging Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Oxford : Oxford University Press |
| مواضيع طبية MeSH: | Acute Coronary Syndrome*/diagnostic imaging , Acute Coronary Syndrome*/physiopathology , Pulmonary Artery*/diagnostic imaging , Pulmonary Artery*/physiopathology , Systole*, Humans ; Male ; Female ; Aged ; Prognosis ; Retrospective Studies ; Middle Aged ; Echocardiography/methods ; Tricuspid Valve/diagnostic imaging ; Tricuspid Valve/physiopathology ; Hospital Mortality ; Prospective Studies ; France ; Hospitalization ; Risk Assessment ; ROC Curve |
| مستخلص: | Aims: Although several studies have shown that the right ventricular to pulmonary artery (RV-PA) coupling, assessed by the ratio between tricuspid annular plane systolic excursion and systolic pulmonary artery pressure (TAPSE/sPAP) using echocardiography, is strongly associated with cardiovascular events, its prognostic value is not established in acute coronary syndrome (ACS). We aimed to assess the in-hospital prognostic value of TAPSE/sPAP among patients hospitalized for ACS in a retrospective analysis from the prospective ADDICT-ICCU study. Methods and Results: A total of 481 consecutive patients hospitalized in intensive cardiac care unit [mean age 65 ± 13 years, 73% of male, 46% ST-elevation myocardial infarction (STEMI)] for ACS [either STEMI or non-STEMI (NSTEMI)] with TAPSE/sPAP available were included in this prospective French multicentric study (39 centres). The primary outcome was in-hospital major adverse cardiovascular events (MACEs) defined as all-cause death, resuscitated cardiac arrest, or cardiogenic shock and occurred in 33 (7%) patients. Receiver operating characteristic curve analysis identified 0.55 mm/mmHg as the best TAPSE/sPAP cut-off to predict in-hospital MACEs. TAPSE/sPAP <0.55 was associated with in-hospital MACEs, even after adjustment with comorbidities [odds ratio (OR): 19.1, 95% confidence interval (CI) 7.78-54.8], clinical severity including left ventricular ejection fraction (OR: 14.4, 95% CI 5.70-41.7), and propensity-matched population analysis (OR: 22.8, 95% CI 7.83-97.2, all P < 0.001). After adjustment, TAPSE/sPAP <0.55 showed the best improvement in model discrimination and reclassification above traditional prognosticators (C-statistic improvement: 0.16; global χ2 improvement: 52.8; likelihood ratio test P < 0.001) with similar results for both STEMI and NSTEMI subgroups. Conclusion: A low RV-PA coupling defined as TAPSE/sPAP ratio <0.55 was independently associated with in-hospital MACEs and provided incremental prognostic value over traditional prognosticators in patients hospitalized for ACS. Trial Registration: ClinicalTrials.gov Identifier: NCT05063097. Competing Interests: Conflict of interest: None declared. (© The Author(s) 2024. Published by Oxford University Press on behalf of the European Society of Cardiology. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com.) |
| معلومات مُعتمدة: | Fondation Coeur et Recherche |
| فهرسة مساهمة: | Investigator: A Victor; A Emeric; A Franck; A Sean; A Nabil; A Stéphane; A Sabir; A Simon; A Sonia; A Ruben; B Marc; B Franck; B Albert; B Thomas; BC Eric; B Guillaume; B Guillaume; B Nabil; B Océane; B Claire; B Tanissia; BB Jean; C Marjorie; C Aures; C Clement; SC Anne; C Alexandre; C Yves; D Arthur; A Elena; D Clément; D Laura; D Antoine; CD Jean; D Jean-Guillaume; D Clemence; D Valentin; E Meyer; EH Antony; EO Amine; E Nacim; F Julien; F Damien; F Charles; G Édouard; G Martine; G Marc; G Nissim; G Alain; HM Marie; H Patrick; H Fabien; L Thomas; L Benoit; L Léo; L Thomas; L Pascal; MB Laura; M Nicolas; M Benjamin; M David; M Benoit; M Christophe; M Damien; M Thomas; N Pascal; N Nathalie; O Patrick; P Théo; P Fabien; P Nicolas; P Thibaut; P Etienne; R Arthur; RV Reza; R François; R Vincent; S Guillaume; S Mathilde; S David; S Fédérico; T Victoria; T Eugénie; T Christophe; T Antonin; T Christophe; V Guillaume; Y Dominique; Z Cyril Keywords: TAPSE/sPAP; acute coronary syndrome; death; echocardiography; prognosis |
| سلسلة جزيئية: | ClinicalTrials.gov NCT05063097 |
| تواريخ الأحداث: | Date Created: 20240423 Date Completed: 20240826 Latest Revision: 20240827 |
| رمز التحديث: | 20240828 |
| DOI: | 10.1093/ehjci/jeae110 |
| PMID: | 38650518 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2047-2412 |
|---|---|
| DOI: | 10.1093/ehjci/jeae110 |