دورية أكاديمية
أعرض في EDS

Outcomes of stereoelectroencephalography following failed epilepsy surgery in children.

التفاصيل البيبلوغرافية
العنوان: Outcomes of stereoelectroencephalography following failed epilepsy surgery in children.
المؤلفون: Wong GM; Department of Neurological Surgery, Georgetown University School of Medicine, Washington, DC, USA. gw294@georgetown.edu., McCray A; Department of Neurosurgery, Children's National Hospital, Washington, DC, 20012, USA., Hom K; Department of Neurology, George Washington University School of Medicine, Washington, DC, USA., Teti S; Department of Neurosurgery, Children's National Hospital, Washington, DC, 20012, USA., Cohen NT; Department of Neurology, George Washington University School of Medicine, Washington, DC, USA.; Department of Neurology, Children's National Hospital, Washington, DC, USA., Gaillard WD; Department of Neurology, George Washington University School of Medicine, Washington, DC, USA.; Department of Neurology, Children's National Hospital, Washington, DC, USA., Oluigbo CO; Department of Neurosurgery, Children's National Hospital, Washington, DC, 20012, USA. COluigbo@childrensnational.org.
المصدر: Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery [Childs Nerv Syst] 2024 Apr 23. Date of Electronic Publication: 2024 Apr 23.
Publication Model: Ahead of Print
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Springer International Country of Publication: Germany NLM ID: 8503227 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1433-0350 (Electronic) Linking ISSN: 02567040 NLM ISO Abbreviation: Childs Nerv Syst Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Berlin : Springer International, c1985-
مستخلص: Introduction: Stereoelectroencephalography (SEEG) is valuable for delineating the seizure onset zone (SOZ) in pharmacoresistant epilepsy when non-invasive presurgical techniques are inconclusive. Secondary epilepsy surgery after initial failure is challenging and there is limited research on SEEG following failed epilepsy surgery in children.
Objective: The objective of this manuscript is to present the outcomes of children who underwent SEEG after failed epilepsy surgery.
Methods: In this single-institution retrospective study, demographics, previous surgery data, SEEG characteristics, management, and follow-up were analyzed for pediatric patients who underwent SEEG after unsuccessful epilepsy surgery between August 2016 and February 2023.
Results: Fifty three patients underwent SEEG investigation during this period. Of this, 13 patients were identified who had unsuccessful initial epilepsy surgery (24%). Of these 13 patients, six patients (46%) experienced unsuccessful resective epilepsy surgery that targeted the temporal lobe, six patients (46%) underwent surgery involving the frontal lobe, and one patient (8%) had laser interstitial thermal therapy (LITT) of the right insula. SEEG in two thirds of patients (4/6) with initial failed temporal resections revealed expanded SOZ to include the insula. All 13 patients (100%) had a subsequent surgery after SEEG which was either LITT (54%) or surgical resection (46%). After the subsequent surgery, a favorable outcome (Engel class I/II) was achieved by eight patients (62%), while five patients experienced an unfavorable outcome (Engel class III/IV, 38%). Of the six patients with secondary surgical resection, four patients (67%) had favorable outcomes, while of the seven patients with LITT, two patients (29%) had favorable outcomes (Engel I/II). Average follow-up after the subsequent surgery was 37 months ±23 months.
Conclusion: SEEG following initial failed resective epilepsy surgery may help guide next steps at identifying residual epileptogenic cortex and is associated with favorable seizure control outcomes.
(© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
References: Harris WB, Brunette-Clement T, Wang A et al (2022) Long-term outcomes of pediatric epilepsy surgery: individual participant data and study level meta-analyses. Seizure Eur J Epilepsy 101:227–236. https://doi.org/10.1016/j.seizure.2022.08.010. (PMID: 10.1016/j.seizure.2022.08.010)
Andrews JP, Gummadavelli A, Farooque P et al (2019) Association of seizure spread with surgical failure in epilepsy. JAMA Neurol 76(4):462–469. https://doi.org/10.1001/jamaneurol.2018.4316. (PMID: 10.1001/jamaneurol.2018.431630508033)
Ryvlin P, Kahane P (2005) The hidden causes of surgery-resistant temporal lobe epilepsy: extratemporal or temporal plus? editorial review. Curr Opin Neurol 18(2):125. https://doi.org/10.1097/01.wco.0000162852.22026.6f. (PMID: 10.1097/01.wco.0000162852.22026.6f15791141)
Jeha LE, Najm IM, Bingaman WE et al (2006) Predictors of outcome after temporal lobectomy for the treatment of intractable epilepsy. Neurology 66(12):1938–1940. https://doi.org/10.1212/01.wnl.0000219810.71010.9b. (PMID: 10.1212/01.wnl.0000219810.71010.9b16801667)
Barba C, Rheims S, Minotti L et al (2016) Temporal plus epilepsy is a major determinant of temporal lobe surgery failures. Brain 139(2):444–451. https://doi.org/10.1093/brain/awv372. (PMID: 10.1093/brain/awv37226700686)
Bartolomei F, Lagarde S, Wendling F et al (2017) Defining epileptogenic networks: contribution of SEEG and signal analysis. Epilepsia 58(7):1131–1147. https://doi.org/10.1111/epi.13791. (PMID: 10.1111/epi.1379128543030)
Yardi R, Morita-Sherman ME, Fitzgerald Z et al (2020) Long-term outcomes of reoperations in epilepsy surgery. Epilepsia 61(3):465–478. https://doi.org/10.1111/epi.16452. (PMID: 10.1111/epi.16452321089467224413)
Khoo HM, Hall JA, Dubeau F et al (2020) Technical aspects of seeg and its interpretation in the delineation of the epileptogenic zone. Neurol Med Chir (Tokyo) 60(12):565–580. https://doi.org/10.2176/nmc.st.2020-0176. (PMID: 10.2176/nmc.st.2020-017633162469)
Iida K, Otsubo H (2017) Stereoelectroencephalography: indication and Efficacy. Neurol Med Chir (Tokyo) 57(8):375–385. https://doi.org/10.2176/nmc.ra.2017-0008. (PMID: 10.2176/nmc.ra.2017-000828637943)
Kovac S, Vakharia VN, Scott C, Diehl B (2017) Invasive epilepsy surgery evaluation. Seizure 44:125–136. https://doi.org/10.1016/j.seizure.2016.10.016. (PMID: 10.1016/j.seizure.2016.10.01627816354)
Jayakar P, Gotman J, Harvey AS et al (2016) Diagnostic utility of invasive EEG for epilepsy surgery: indications, modalities, and techniques. Epilepsia 57(11):1735–1747. https://doi.org/10.1111/epi.13515. (PMID: 10.1111/epi.1351527677490)
Vaugier L, Lagarde S, McGonigal A et al (2018) The role of stereoelectroencephalography (SEEG) in reevaluation of epilepsy surgery failures. Epilepsy Behav EB 81:86–93. https://doi.org/10.1016/j.yebeh.2018.02.005. (PMID: 10.1016/j.yebeh.2018.02.005)
Najm I, Lal D, Alonso Vanegas M et al (2022) The ILAE consensus classification of focal cortical dysplasia: an update proposed by an ad hoc task force of the ILAE diagnostic methods commission. Epilepsia 63(8):1899–1919. https://doi.org/10.1111/epi.17301. (PMID: 10.1111/epi.17301357061319545778)
Engel J Jr, Van Ness PC, Rasmussen TB, Ojemann LM (1993) Outcome with respect to epileptic seizures. In: Engel J Jr (ed) Surgical treatment of the epilepsies, ed 2. Raven Press, pp 609–621.
Kim SK, Wang KC, Hwang YS et al (2008) Epilepsy surgery in children: outcomes and complications. J Neurosurg Pediatr 1(4):277–283. https://doi.org/10.3171/PED/2008/1/4/277. (PMID: 10.3171/PED/2008/1/4/27718377302)
Englot DJ, Han SJ, Rolston JD et al (2014) Epilepsy surgery failure in children: a quantitative and qualitative analysis: clinical article. J Neurosurg Pediatr 14(4):386–395. https://doi.org/10.3171/2014.7.PEDS13658. (PMID: 10.3171/2014.7.PEDS13658251270984393949)
McIntosh AM, Kalnins RM, Mitchell LA, Fabinyi GCA, Briellmann RS, Berkovic SF (2004) Temporal lobectomy: long-term seizure outcome, late recurrence and risks for seizure recurrence. Brain 127(9):2018–2030. https://doi.org/10.1093/brain/awh221. (PMID: 10.1093/brain/awh22115215219)
Wiebe S, Blume WT, Girvin JP, Eliasziw M (2001) A randomized, controlled trial of surgery for temporal-lobe epilepsy. N Engl J Med 345(5):311–318. https://doi.org/10.1056/NEJM200108023450501. (PMID: 10.1056/NEJM20010802345050111484687)
Harroud A, Bouthillier A, Weil AG, Nguyen DK (2012) Temporal lobe epilepsy surgery failures: a review. Epilepsy Res Treat 2012:201651. https://doi.org/10.1155/2012/201651. (PMID: 10.1155/2012/201651229341623420575)
Li J, Reiter-Campeau S, Namiranian D et al (2022) Insular involvement in cases of epilepsy surgery failure. Brain Sci 12(2):125. https://doi.org/10.3390/brainsci12020125. (PMID: 10.3390/brainsci12020125352038898870364)
Obaid S, Zerouali Y, Nguyen DK (2017) Insular epilepsy: semiology and noninvasive investigations. J Clin Neurophysiol Off Publ Am Electroencephalogr Soc 34(4):315–323. https://doi.org/10.1097/WNP.0000000000000396. (PMID: 10.1097/WNP.0000000000000396)
Cohen NT, Chang P, You X et al (2022) Prevalence and risk factors for pharmacoresistance in children with focal cortical dysplasia-related epilepsy. Neurology 99(18):e2006-2013. https://doi.org/10.1212/WNL.0000000000201033. (PMID: 10.1212/WNL.0000000000201033359858319651467)
Holthausen H, Pieper T, Winkler P, Bluemcke I, Kudernatsch M (2014) Electro-clinical-pathological correlations in focal cortical dysplasia (FCD) at young ages. Childs Nerv Syst 30(12):2015–2026. https://doi.org/10.1007/s00381-014-2549-6. (PMID: 10.1007/s00381-014-2549-625255773)
Jayalakshmi S, Vooturi S, Vadapalli R, Madigubba S, Panigrahi M (2021) Predictors of surgical outcome in focal cortical dysplasia and its subtypes. J Neurosurg 136(2):512–522. https://doi.org/10.3171/2020.12.JNS203385. (PMID: 10.3171/2020.12.JNS20338534330093)
Krsek P, Pieper T, Karlmeier A et al (2009) Different presurgical characteristics and seizure outcomes in children with focal cortical dysplasia type I or II. Epilepsia 50(1):125–137. https://doi.org/10.1111/j.1528-1167.2008.01682.x. (PMID: 10.1111/j.1528-1167.2008.01682.x18513354)
Cohen NT, Ziobro JM, Depositario-Cabacar DF et al (2020) Measure thrice, cut twice: on the benefit of reoperation for failed pediatric epilepsy surgery. Epilepsy Res 161:106289. https://doi.org/10.1016/j.eplepsyres.2020.106289. (PMID: 10.1016/j.eplepsyres.2020.10628932088518)
Chen H, Modur PN, Barot N et al (2016) Predictors of postoperative seizure recurrence: a longitudinal study of temporal and extratemporal resections. Epilepsy Res Treat 2016:7982494. https://doi.org/10.1155/2016/7982494. (PMID: 10.1155/2016/7982494270696824812270)
Hale AT, Sen S, Haider AS et al (2019) Open resection versus laser interstitial thermal therapy for the treatment of pediatric insular epilepsy. Neurosurgery 85(4):E730–E736. https://doi.org/10.1093/neuros/nyz094. (PMID: 10.1093/neuros/nyz094308880286748806)
Drane DL, Loring DW, Voets NL et al (2015) Better object recognition and naming outcome with MRI-guided stereotactic laser amygdalohippocampotomy for temporal lobe epilepsy. Epilepsia 56(1):101–113. https://doi.org/10.1111/epi.12860. (PMID: 10.1111/epi.1286025489630)
Hoppe C, Helmstaedter C (2020) Laser interstitial thermotherapy (LiTT) in pediatric epilepsy surgery. Seizure 77:69–75. https://doi.org/10.1016/j.seizure.2018.12.010. (PMID: 10.1016/j.seizure.2018.12.01030591281)
فهرسة مساهمة: Keywords: Epilepsy surgery; Failed surgery; Pediatrics; Seizures
تواريخ الأحداث: Date Created: 20240423 Latest Revision: 20240423
رمز التحديث: 20240424
DOI: 10.1007/s00381-024-06420-w
PMID: 38652142
قاعدة البيانات: MEDLINE
الوصف
تدمد:1433-0350
DOI:10.1007/s00381-024-06420-w