دورية أكاديمية
The Introduction of Magtrace® Lymphatic Tracer for Axillary Sentinel Node Biopsy for Breast Cancer in a Rural Scottish District General Hospital: Initial Experience, Perspectives, Outcomes and Learning Curves.
| العنوان: | The Introduction of Magtrace® Lymphatic Tracer for Axillary Sentinel Node Biopsy for Breast Cancer in a Rural Scottish District General Hospital: Initial Experience, Perspectives, Outcomes and Learning Curves. |
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| المؤلفون: | Kong CY; Department of Surgery, Dumfries and Galloway Royal Infirmary, Dumfries, UK; Academic Unit of Surgery, Glasgow Royal Infirmary and University of Glasgow, Glasgow, UK. Electronic address: nicholascykong@gmail.com., Williams J; Department of Surgery, Dumfries and Galloway Royal Infirmary, Dumfries, UK., Hemadasa N; Department of Surgery, Dumfries and Galloway Royal Infirmary, Dumfries, UK., Murphy D; Department of Surgery, Dumfries and Galloway Royal Infirmary, Dumfries, UK., Bews-Hair M; Department of Surgery, Dumfries and Galloway Royal Infirmary, Dumfries, UK. |
| المصدر: | Clinical breast cancer [Clin Breast Cancer] 2024 Aug; Vol. 24 (6), pp. e495-e502. Date of Electronic Publication: 2024 Mar 30. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: United States NLM ID: 100898731 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1938-0666 (Electronic) Linking ISSN: 15268209 NLM ISO Abbreviation: Clin Breast Cancer Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2011- : [New York] : Elsevier Original Publication: Dallas, Tex. : Cancer Information Group |
| مواضيع طبية MeSH: | Breast Neoplasms*/pathology , Sentinel Lymph Node Biopsy*/methods , Sentinel Lymph Node Biopsy*/statistics & numerical data , Learning Curve* , Axilla*, Humans ; Female ; Prospective Studies ; Middle Aged ; Aged ; Adult ; Hospitals, General ; Lymph Nodes/pathology ; Lymph Nodes/diagnostic imaging ; Lymphatic Metastasis/pathology ; Sentinel Lymph Node/pathology ; Sentinel Lymph Node/diagnostic imaging ; Sentinel Lymph Node/surgery ; Aged, 80 and over ; Technetium Tc 99m Aggregated Albumin ; Hospitals, District |
| مستخلص: | Background: Magtrace is a supraparamagnetic iron lymphatic tracer that has had increasing use in sentinel node biopsy (SNB) for breast cancer and has theoretical logistical benefits in centres where nanocolloid use may be associated with such issues. We describe our initial experience with the introduction of Magtrace into our routine practice by dual localisation with nanocolloid, comparing performance, and concordance. Materials and Methods: This was prospective study of the first patients undergoing axillary SNB using Magtrace in a single centre. These patients had dual localisation with nanocolloid and Magtrace. Subjective global assessments of Magtrace and nanocolloid performance as well as objective signal strength and anatomical concordance were compared across multiple timepoints in the operative journey. Results: A total of 30 consecutive patients underwent SNB within the timeframe of this study. While there were no failed SNB, 8 issues were reported including 4 issues of perceived imperfect localisation on global assessment. No patient had a failed or abandoned SNB, and only 1 case had a potential challenge in subsequent management after histopathological examination of the retrieved nodes. The majority of these issues occurred in the first half of the study period. There was overall weak to moderate positive correlation between Magtrace and nanocolloid signals of the retrieved sentinel nodes (Spearman's ρ = 0.392, P = .043). Conclusion: This study suggests that introducing Magtrace was feasible and safe in the context of a rural breast cancer service. A possible strategy to ameliorate the learning curve associated with these procedures is the routine dual localisation in the initial phases of performing Magtrace localisation. Competing Interests: Disclosure There was no specific funding for this study. DM has previously consulted for Endomag and the National Institute of Clinical Excellence (NICE), United Kingdom. The other authors have no conflicts of interests to declare. (Copyright © 2024 The Author(s). Published by Elsevier Inc. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Axillary management; Breast surgery; Lymph node biopsy |
| المشرفين على المادة: | 0 (Technetium Tc 99m Aggregated Albumin) |
| تواريخ الأحداث: | Date Created: 20240423 Date Completed: 20240728 Latest Revision: 20240728 |
| رمز التحديث: | 20240729 |
| DOI: | 10.1016/j.clbc.2024.03.013 |
| PMID: | 38653647 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 1938-0666 |
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| DOI: | 10.1016/j.clbc.2024.03.013 |