دورية أكاديمية
Physical Activity at Different Life Stages and Its Consequence on the Initial Immunization and Inflammatory Response Against COVID-19.
| العنوان: | Physical Activity at Different Life Stages and Its Consequence on the Initial Immunization and Inflammatory Response Against COVID-19. |
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| المؤلفون: | Rossi PAQ; Postgraduation Student in Science and Health, Federal University of Piaui, Teresina, PI, Brazil.; Department of Biophysics and Physiology, Nucleus of Study in Physiology Applied to Performance and Health (NEFADS), Federal University of Piaui, Teresina, PI, Brazil., Gomes R; Biotecnologia, Escritório Técnico da Fiocruz Ceará, Eusébio, CE, Brazil., Nascimento Salazar TCD; Postgraduation Student in Science and Health, Federal University of Piaui, Teresina, PI, Brazil.; Department of Biophysics and Physiology, Nucleus of Study in Physiology Applied to Performance and Health (NEFADS), Federal University of Piaui, Teresina, PI, Brazil., Lustosa Barros EM; Department of Biophysics and Physiology, Nucleus of Study in Physiology Applied to Performance and Health (NEFADS), Federal University of Piaui, Teresina, PI, Brazil., Vasconcelos S; Escritório Técnico da Fiocruz Piauí, Teresina, PI, Brazil., da Silva AS; Federal University of Piauí (UFPI), Teresina, PI, Brazil., Pereira EM; Secretaria de Estado da Saúde do Piauí, Teresina, PI, Brazil., Melo VB; Unidade de Apoio ao Diagnóstico de Covid-19 (UNADIG), Fiocruz Ceará, Eusébio, CE, Brazil., Fonseca MHG; Unidade de Apoio ao Diagnóstico de Covid-19 (UNADIG), Fiocruz Ceará, Eusébio, CE, Brazil., Teixeira CR; Biotecnologia, Escritório Técnico da Fiocruz Ceará, Eusébio, CE, Brazil., Furtado GP; Biotecnologia, Escritório Técnico da Fiocruz Ceará, Eusébio, CE, Brazil., Pontes LQ; Biotecnologia, Escritório Técnico da Fiocruz Ceará, Eusébio, CE, Brazil., Khouri R; Gonçalo Moniz Institute, Fiocruz Bahia, Salvador, BA, Brazil.; Faculty of Medicine, Federal University of Bahia, Salvador,BA, Brazil., Vasconcelos B; Gonçalo Moniz Institute, Fiocruz Bahia, Salvador, BA, Brazil.; Faculty of Medicine, Federal University of Bahia, Salvador,BA, Brazil., Almeida SS; Department of Obstetrician, Escola Paulista de Medicina, Universidade Federal de São Paulo (UNIFESP), São Paulo,SP, Brazil.; Faculdade Anhanguera de Guarulhos, Guarulhos,SP, Brazil.; Hospital Israelita Albert Einstein, São Paulo, SP, Brazil., Werneck GL; Universidade Estadual do Rio de Janeiro, Rio de Janeiro, RJ, Brazil., Rossi FE; Department of Physical Education, Immunometabolism of Skeletal Muscle and Exercise Research Group, São Paulo State University (UNESP), Presidente Prudente, SP, Brazil.; Graduate Program in Science and Health, Federal University of Piauí (UFPI), Teresina, PI, Brazil.; Graduate Program in Movement Science, São Paulo State University (UNESP), Presidente Prudente, SP, Brazil., Santos MAPD; Department of Biophysics and Physiology, Nucleus of Study in Physiology Applied to Performance and Health (NEFADS), Federal University of Piaui, Teresina, PI, Brazil. |
| المصدر: | Journal of physical activity & health [J Phys Act Health] 2024 Apr 24; Vol. 21 (7), pp. 717-725. Date of Electronic Publication: 2024 Apr 24 (Print Publication: 2024). |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Human Kinetics Publishers Country of Publication: United States NLM ID: 101189457 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1543-5474 (Electronic) Linking ISSN: 15433080 NLM ISO Abbreviation: J Phys Act Health Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Champaign, IL : Human Kinetics Publishers, c2004- |
| مواضيع طبية MeSH: | Exercise* , COVID-19*/prevention & control , COVID-19*/immunology , Antibodies, Viral*/blood , SARS-CoV-2*/immunology, Humans ; Male ; Female ; Adult ; Adolescent ; COVID-19 Vaccines/immunology ; COVID-19 Vaccines/administration & dosage ; Immunoglobulin G/blood ; Immunoglobulin G/immunology ; Cytokines/blood ; Child ; Middle Aged ; Young Adult ; Inflammation/immunology ; Age Factors |
| مستخلص: | Background: To evaluate the influence of previous physical activity (PA) during childhood, adolescence, and current PA practice on the production of antibodies and inflammatory response between the first and second doses of the COVID-19 vaccine. Methods: Fifty-nine men and 56 women were evaluated before the first vaccine, and 12 weeks later, blood samples were taken to quantify production of anti-severe acute respiratory syndrome coronavirus-2 immunoglobulin G antibodies and cytokines. Previous PA during childhood and adolescence was self-referred, and current PA was assessed using the International Physical Activity Questionnaire. Results: A positive and significant association was observed only between PA practice during adolescence and an increase in antibody production in adulthood (β = 2012.077, 95% confidence interval, 257.7953-3766.358, P = .025). Individuals who practiced PA during adolescence showed higher production of antibodies between the first and second vaccine dose compared to nonpractitioners (P = .025) and those that accumulated ≥150 minutes per week of current moderate-vigorous PA (MVPA), and presented higher antibody production in relation to who did <150 minutes per week of MVPA (P = .046). Individuals that were practitioners during childhood produced higher G-CSF (P = .047), and those that accumulated ≥150 minutes per week of current MVPA demonstrated lower IP-10 levels (P = .033). However, PA practitioners during adolescence presented higher G-CSF (P = .025), IL-17 (P = .038), IL-1RA (P = .005), IL-1β (P = .020), and IL-2 (P = .026) levels. Conclusion: Our results suggest that adults that accumulated at least 150 minutes of MVPA per week or practiced PA during adolescence developed an improved immune and inflammatory response against COVID-19 vaccination. |
| فهرسة مساهمة: | Keywords: antibodies; exercise; teenager; vaccine |
| المشرفين على المادة: | 0 (Antibodies, Viral) 0 (COVID-19 Vaccines) 0 (Immunoglobulin G) 0 (Cytokines) |
| تواريخ الأحداث: | Date Created: 20240425 Date Completed: 20240624 Latest Revision: 20240624 |
| رمز التحديث: | 20240624 |
| DOI: | 10.1123/jpah.2023-0370 |
| PMID: | 38663845 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1543-5474 |
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| DOI: | 10.1123/jpah.2023-0370 |