دورية أكاديمية
Chromogenic Detection of the Organophosphorus Nerve Agent Simulant DCP Mediated by Rhodium(II,II) Paddlewheel Complexes.
| العنوان: | Chromogenic Detection of the Organophosphorus Nerve Agent Simulant DCP Mediated by Rhodium(II,II) Paddlewheel Complexes. |
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| المؤلفون: | Fussell ED; Department of Chemistry, University of Tennessee, 1420 Circle Drive, Knoxville, Tennessee 37996, United States., Kline ND; Combat Capabilities Development Command Chemical Biological Center, Aberdeen Proving Ground, Maryland 21010-5424, United States., Bennin E; Department of Chemistry, University of Tennessee, 1420 Circle Drive, Knoxville, Tennessee 37996, United States., Hirschbeck SS; Department of Chemistry, University of Tennessee, 1420 Circle Drive, Knoxville, Tennessee 37996, United States., Darko A; Department of Chemistry, University of Tennessee, 1420 Circle Drive, Knoxville, Tennessee 37996, United States. |
| المصدر: | ACS sensors [ACS Sens] 2024 May 24; Vol. 9 (5), pp. 2325-2333. Date of Electronic Publication: 2024 Apr 26. |
| نوع المنشور: | Journal Article; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 101669031 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2379-3694 (Electronic) Linking ISSN: 23793694 NLM ISO Abbreviation: ACS Sens Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Washington, DC : American Chemical Society, [2016]- |
| مواضيع طبية MeSH: | Rhodium*/chemistry , Nerve Agents*/analysis , Nerve Agents*/chemistry, Coordination Complexes/chemistry ; Organophosphorus Compounds/analysis ; Organophosphorus Compounds/chemistry ; Limit of Detection ; Chromogenic Compounds/chemistry ; Chemical Warfare Agents/analysis ; Chemical Warfare Agents/chemistry |
| مستخلص: | Organophosphorus nerve agents (OPNAs) pose a great threat to humanity. Possessing extreme toxicity, rapid lethality, and an unassuming appearance, these chemical warfare agents must be quickly and selectively identified so that treatment can be administered to those affected. Chromogenic detection is the most convenient form of OPNA detection, but current methods suffer from false positives. Here, nitrogenous base adducts of dirhodium(II,II) acetate were synthesized and used as chromogenic detectors of diethyl chlorophosphate (DCP), an OPNA simulant. UV-vis spectrophotometry was used to evaluate the sensitivity and selectivity of the complexes in the detection of DCP. Visual limits of detection (LOD) for DCP were as low as 1.5 mM DCP, while UV-vis-based LODs were as low as 0.113 μM. The dirhodium(II,II) complexes were also tested with several potential interferents, none of which produced a visual color change that could be mistaken for OPNA response. Ultimately, the Rh |
| فهرسة مساهمة: | Keywords: chemosensor; chromogenic; detection; nerve agents; paddlewheel; rhodium |
| المشرفين على المادة: | DMK383DSAC (Rhodium) 0 (Nerve Agents) 0 (diethylchlorophosphate) 0 (Coordination Complexes) 0 (Organophosphorus Compounds) 0 (Chromogenic Compounds) 0 (Chemical Warfare Agents) |
| تواريخ الأحداث: | Date Created: 20240426 Date Completed: 20240524 Latest Revision: 20240618 |
| رمز التحديث: | 20240618 |
| DOI: | 10.1021/acssensors.3c01993 |
| PMID: | 38666660 |
| قاعدة البيانات: | MEDLINE |
Find this issue from the American Chemical Society | تدمد: | 2379-3694 |
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| DOI: | 10.1021/acssensors.3c01993 |