دورية أكاديمية
أعرض في EDS

Treating Pythiosis with Antibacterial Drugs Targeting Protein Synthesis: An Overview.

التفاصيل البيبلوغرافية
العنوان: Treating Pythiosis with Antibacterial Drugs Targeting Protein Synthesis: An Overview.
المؤلفون: Loreto ES; Sobresp Faculty of Health Sciences, 520 Appel Street, Santa Maria 97015-030, RS, Brazil., Tondolo JSM; Sobresp Faculty of Health Sciences, 520 Appel Street, Santa Maria 97015-030, RS, Brazil., Zanette RA; Department of Pharmacology, Basic Health Sciences Institute, Federal University of Rio Grande do Sul, 2600 Ramiro Barcelos Street, Porto Alegre 90035-003, RS, Brazil.
المصدر: Journal of fungi (Basel, Switzerland) [J Fungi (Basel)] 2024 Mar 22; Vol. 10 (4). Date of Electronic Publication: 2024 Mar 22.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101671827 Publication Model: Electronic Cited Medium: Internet ISSN: 2309-608X (Electronic) Linking ISSN: 2309608X NLM ISO Abbreviation: J Fungi (Basel) Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI AG, [2015]-
مستخلص: This review article explores the effectiveness of antibacterial drugs that inhibit protein synthesis in treating pythiosis, a difficult-to-treat infection caused by Pythium insidiosum . The article highlights the susceptibility of P. insidiosum to antibacterial drugs, such as macrolides, oxazolidinones, and tetracyclines. We examine various studies, including in vitro tests, experimental infection models, and clinical case reports. Based on our synthesis of these findings, we highlight the potential of these drugs in managing pythiosis, primarily when combined with surgical interventions. The review emphasizes the need for personalized treatment strategies and further research to establish standardized testing protocols and optimize therapeutic approaches.
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فهرسة مساهمة: Keywords: Pythiosis treatment; Pythium insidiosum; azithromycin; linezolid; protein-inhibiting antibacterials
تواريخ الأحداث: Date Created: 20240426 Latest Revision: 20240428
رمز التحديث: 20240428
مُعرف محوري في PubMed: PMC11051233
DOI: 10.3390/jof10040234
PMID: 38667905
قاعدة البيانات: MEDLINE
الوصف
تدمد:2309-608X
DOI:10.3390/jof10040234