دورية أكاديمية
أعرض في EDS

Squamous Cell Carcinoma Arising From Epidermal Cyst: A Case Series of 9 Patients With a Literature Review.

التفاصيل البيبلوغرافية
العنوان: Squamous Cell Carcinoma Arising From Epidermal Cyst: A Case Series of 9 Patients With a Literature Review.
المؤلفون: Kim JY; From the Department of Plastic and Reconstructive Surgery, Seoul National University College of Medicine, Seoul., Min S; From the Department of Plastic and Reconstructive Surgery, Seoul National University College of Medicine, Seoul., Park JK; Department of Plastic and Reconstructive Surgery, Seoul National University Bundang Hospital, Seongnam, Republic of Korea., Kim SW; From the Department of Plastic and Reconstructive Surgery, Seoul National University College of Medicine, Seoul.
المصدر: Annals of plastic surgery [Ann Plast Surg] 2024 May 01; Vol. 92 (5), pp. 575-579. Date of Electronic Publication: 2024 Mar 26.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: Little, Brown And Company Country of Publication: United States NLM ID: 7805336 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1536-3708 (Electronic) Linking ISSN: 01487043 NLM ISO Abbreviation: Ann Plast Surg Subsets: MEDLINE
أسماء مطبوعة: Publication: Boston Ma : Little, Brown And Company
Original Publication: Boston, Little, Brown.
مواضيع طبية MeSH: Carcinoma, Squamous Cell*/surgery , Carcinoma, Squamous Cell*/pathology , Epidermal Cyst*/surgery , Epidermal Cyst*/pathology , Skin Neoplasms*/pathology , Skin Neoplasms*/surgery, Adult ; Aged ; Female ; Humans ; Male ; Middle Aged ; Cell Transformation, Neoplastic/pathology ; Retrospective Studies ; Young Adult ; Aged, 80 and over
مستخلص: Abstract: Epidermal cysts are among the most common benign subcutaneous tumors. However, malignant transformation of benign epidermal cysts into squamous carcinomas has been reported. Owing to its low incidence rate, the clinical and pathological features of this condition are not well understood. This study aimed to analyze the clinical and pathological characteristics of the malignant transformation of epidermal cysts, which could suggest an appropriate treatment strategy. We conducted a retrospective study of 9 patients diagnosed with squamous cell carcinoma arising from epidermal cysts. All patients underwent surgical excision, and clinical information regarding patient demographics, tumor characteristics, treatment, and outcomes was analyzed. The average age at diagnosis was 57.3 years, with an average latency period of 15.4 years. Five patients had undergone prior cyst excision or drainage, with an average of 2.3 episodes of recurrence. Surgical excision was the primary treatment in all cases, and 2 patients with margin involvement at the final pathology underwent re-excision with additional resection margins. No recurrence was observed during the follow-up period. Four patients had immune dysregulation due to an underlying chronic kidney disease or cancer. Our study emphasizes the need for increased awareness of squamous cell carcinoma arising from epidermal cysts in patients with a history of cyst existence or recurrence, especially those with immune deficiencies. We expect these findings to contribute to early suspicion of malignant transformation and guide adequate clinical decision-making.
Competing Interests: Conflicts of interest and sources of funding: none declared.
(Copyright © 2024 The Author(s). Published by Wolters Kluwer Health, Inc.)
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تواريخ الأحداث: Date Created: 20240426 Date Completed: 20240430 Latest Revision: 20240502
رمز التحديث: 20240502
DOI: 10.1097/SAP.0000000000003880
PMID: 38669586
قاعدة البيانات: MEDLINE
الوصف
تدمد:1536-3708
DOI:10.1097/SAP.0000000000003880