دورية أكاديمية
أعرض في EDS

Pre- and Post-COVID-19 Antimicrobial Resistance Pattern of Pathogens in an Intensive Care Unit.

التفاصيل البيبلوغرافية
العنوان: Pre- and Post-COVID-19 Antimicrobial Resistance Pattern of Pathogens in an Intensive Care Unit.
المؤلفون: Golli AL; Department of Public Health and Management, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania., Zlatian OM; Department of Microbiology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania., Cara ML; Department of Public Health and Management, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania., Olteanu M; Department of Orthodontics, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
المصدر: Pharmaceuticals (Basel, Switzerland) [Pharmaceuticals (Basel)] 2024 Mar 22; Vol. 17 (4). Date of Electronic Publication: 2024 Mar 22.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101238453 Publication Model: Electronic Cited Medium: Print ISSN: 1424-8247 (Print) Linking ISSN: 14248247 NLM ISO Abbreviation: Pharmaceuticals (Basel) Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI, c2004-
مستخلص: We aimed to determine the trend of the antimicrobial resistance pattern of pathogens isolated in samples collected from patients hospitalized in the intensive care unit (ICU) in selected periods before and after COVID-19. A retrospective study of bacterial pathogens was performed on 1267 patients. Positive bacterial culture data from 1695 samples from the pre-COVID-19 period and 1562 samples from the post-COVID-19 period were obtained. The most frequently isolated bacteria in both periods were Staphylococcus aureus and Klebsiella spp. The resistance rates of Klebsiella spp. Significantly increased against colistin (0.38% to 20.51%), gentamicin (44.62% to 64.85%), and aztreonam (56.35% to 3.60%). There was a significant increase in the resistance rate against colistin for E. coli strains (4.69% to 32.46%) and for Acinetobacter sp. strains (3.37% to 18.09%). More than 50% of the Staphylococcus aureus strains were MRSA, with statistically significant increases in the antimicrobial resistance rate against doxycycline (40.08% to 51.72%), linezolid (0.22% to 3.13%), rifampicin (53.16% to 64.93%), and teicoplanin (26.31% to 53.40%). The study revealed a significantly increasing trend in the antimicrobial resistance rate of Gram-negative pathogens against certain antibiotics, including those used only in cases where there are no other therapeutic options.
References: Antibiotics (Basel). 2023 May 23;12(6):. (PMID: 37370266)
Curr Infect Dis Rep. 2022;24(11):175-186. (PMID: 36211535)
Viruses. 2023 Aug 30;15(9):. (PMID: 37766250)
Pathogens. 2022 Oct 28;11(11):. (PMID: 36365001)
Virusdisease. 2021 Jun;32(2):330-337. (PMID: 34056051)
J Infect Public Health. 2021 May;14(5):570-576. (PMID: 33848886)
Antibiotics (Basel). 2022 Mar 10;11(3):. (PMID: 35326839)
J Clin Lab Anal. 2023 Aug;37(15-16):e24959. (PMID: 37650531)
Antibiotics (Basel). 2022 Dec 28;12(1):. (PMID: 36671246)
Health Sci Rep. 2023 Mar 15;6(3):e1153. (PMID: 36938144)
J Infect Public Health. 2023 Apr;16(4):611-617. (PMID: 36857834)
Antibiotics (Basel). 2023 Aug 03;12(8):. (PMID: 37627698)
BMJ. 2007 Oct 20;335(7624):806-8. (PMID: 17947786)
Antimicrob Resist Infect Control. 2022 Oct 1;11(1):121. (PMID: 36182905)
Clin Microbiol Infect. 2012 Mar;18(3):268-81. (PMID: 21793988)
J Clin Med. 2022 Dec 04;11(23):. (PMID: 36498781)
J Infect Dev Ctries. 2023 May 31;17(5):597-609. (PMID: 37279421)
Sci Transl Med. 2018 Aug 1;10(452):. (PMID: 30068573)
Pathogens. 2023 May 30;12(6):. (PMID: 37375470)
Antibiotics (Basel). 2022 Jun 20;11(6):. (PMID: 35740232)
Exp Ther Med. 2018 Dec;16(6):4499-4510. (PMID: 30542398)
Antibiotics (Basel). 2022 Jul 09;11(7):. (PMID: 35884179)
Rev Panam Salud Publica. 2023 Apr 19;47:e10. (PMID: 37082532)
Infect Drug Resist. 2022 Oct 17;15:5981-5992. (PMID: 36262597)
فهرسة مساهمة: Keywords: COVID-19; antimicrobial resistance; pandemic; pathogens
تواريخ الأحداث: Date Created: 20240427 Latest Revision: 20240429
رمز التحديث: 20240429
مُعرف محوري في PubMed: PMC11054378
DOI: 10.3390/ph17040407
PMID: 38675369
قاعدة البيانات: MEDLINE
الوصف
تدمد:1424-8247
DOI:10.3390/ph17040407