دورية أكاديمية
أعرض في EDS

Association of Neoadjuvant Chemotherapy With Postoperative Outcomes in Immediate Prepectoral Prosthetic Breast Reconstruction.

التفاصيل البيبلوغرافية
العنوان: Association of Neoadjuvant Chemotherapy With Postoperative Outcomes in Immediate Prepectoral Prosthetic Breast Reconstruction.
المؤلفون: Choi JM; From the Department of Plastic and Reconstructive Surgery, Myong-Ji Hospital, Myong-Ji Medical Foundation, Goyang., Lee JK; Department of Plastic Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea., Pyon JK; Department of Plastic Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea., Mun GH; Department of Plastic Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea., Jeon BJ; Department of Plastic Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea., Lee KT; Department of Plastic Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
المصدر: Annals of plastic surgery [Ann Plast Surg] 2024 May 01; Vol. 92 (5), pp. 514-521.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Little, Brown And Company Country of Publication: United States NLM ID: 7805336 Publication Model: Print Cited Medium: Internet ISSN: 1536-3708 (Electronic) Linking ISSN: 01487043 NLM ISO Abbreviation: Ann Plast Surg Subsets: MEDLINE
أسماء مطبوعة: Publication: Boston Ma : Little, Brown And Company
Original Publication: Boston, Little, Brown.
مواضيع طبية MeSH: Neoadjuvant Therapy* , Breast Neoplasms*/surgery , Postoperative Complications*/epidemiology , Postoperative Complications*/etiology, Humans ; Female ; Retrospective Studies ; Middle Aged ; Adult ; Breast Implantation/methods ; Propensity Score ; Chemotherapy, Adjuvant ; Mammaplasty/methods ; Treatment Outcome ; Mastectomy, Simple ; Breast Implants
مستخلص: Purpose: Neoadjuvant chemotherapy (NACT) followed by total mastectomy and immediate reconstruction has become an important strategy in the treatment of breast cancer. Although the safety of subpectoral implant-based breast reconstruction with NACT has been extensively evaluated, the safety in prepectoral reconstruction has not been clearly elucidated. We aimed to evaluate the association of NACT with immediate prepectoral breast reconstruction outcomes.
Methods: A retrospective review of patients who underwent total mastectomy and immediate implant-based prepectoral breast reconstruction between May and December 2021 was conducted. Patients were categorized into 2 groups: those receiving NACT and those not receiving it. Postoperative complication rates were compared between the 2 groups. The independent association between NACT and the complication profiles was evaluated. Propensity score matching was also conducted.
Results: We analyzed 343 cases, including 85 who received NACT treatment and 258 who did not. Compared with the non-NACT group, the NACT group was younger, had a higher body mass index, and a higher rate of adjuvant radiotherapy. There were no differences in the rates of overall complications or type of complication between the 2 groups. In the multivariable logistic analyses, NACT did not show a significant association with the development of adverse outcomes. Similar results were observed in propensity score matching analyses.
Conclusions: Our results suggest that receiving NACT may not have a significant detrimental effect on the postoperative outcomes of immediate prepectoral prosthetic reconstructions. Conducting prepectoral implant-based reconstruction in the setting of NACT might be safe and provide acceptable outcomes.
Competing Interests: Conflicts of interest and sources of funding: none declared.
(Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.)
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تواريخ الأحداث: Date Created: 20240430 Date Completed: 20240430 Latest Revision: 20240430
رمز التحديث: 20240501
DOI: 10.1097/SAP.0000000000003887
PMID: 38685491
قاعدة البيانات: MEDLINE
الوصف
تدمد:1536-3708
DOI:10.1097/SAP.0000000000003887