دورية أكاديمية
Contribution of CT scan to patient's radiation exposure in parathyroid SPECT/CT scintigraphy.
| العنوان: | Contribution of CT scan to patient's radiation exposure in parathyroid SPECT/CT scintigraphy. |
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| المؤلفون: | Rep S; Department of Nuclear Medicine, University Medical Centre Ljubljana, Slovenia; University of Ljubljana, Faculty of Health Sciences, Slovenia. Electronic address: sebastijan.rep@guest.arnes.si., Jensterle L; Department of Nuclear Medicine, University Medical Centre Ljubljana, Slovenia., Zdešar U; Institute of Occupational Safety, Ljubljana, Slovenia., Zaletel K; Department of Nuclear Medicine, University Medical Centre Ljubljana, Slovenia; Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia., Tomše P; Department of Nuclear Medicine, University Medical Centre Ljubljana, Slovenia., Ležaič L; Department of Nuclear Medicine, University Medical Centre Ljubljana, Slovenia; Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia. |
| المصدر: | Radiography (London, England : 1995) [Radiography (Lond)] 2024 May; Vol. 30 (3), pp. 995-1000. Date of Electronic Publication: 2024 Apr 29. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 9604102 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-2831 (Electronic) Linking ISSN: 10788174 NLM ISO Abbreviation: Radiography (Lond) Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2003- : Amsterdam : Elsevier B.V. Original Publication: London ; Philadelphia : W.B. Saunders Co., c1995- |
| مواضيع طبية MeSH: | Single Photon Emission Computed Tomography Computed Tomography*/methods , Radiopharmaceuticals* , Radiation Exposure*, Humans ; Male ; Female ; Middle Aged ; Technetium Tc 99m Sestamibi ; Aged ; Radiation Dosage ; Adult ; Parathyroid Glands/diagnostic imaging ; Retrospective Studies ; Tomography, X-Ray Computed/methods |
| مستخلص: | Introduction: Dual phase technetium-99mTc-methoxy isobutyl isonitrile (MIBI) single-photon emission computed tomography with computed tomography (SPECT/CT) may be the most accurate conventional imaging approach for localization of enlarged parathyroid gland (EPG). The imaging is based on the radiopharmaceutical (RP) retention in EPG compared to washout from normal thyroid and normal parathyroid glands. This study aimed to estimate and optimize the contribution of computed tomography (CT) scan and scan range to effective dose (ED) in dual-phase MIBI SPECT/CT parathyroid scintigraphy. Methods: The study included seventy-four patients; thirty-seven with reduced and thirty-seven with extended CT scan range. The ED caused by the CT scan was calculated using Dose Length Product (DLP) data and estimated using the Imaging Performance Assessment of CT scanners (ImPACT) calculator. Results: For all patients, the contribution of CT to the ED in a combined SPECT/CT examination was 2.62 ± 0.29 mSv (48%). The contribution of CT to the total ED was 1.8 ± 0.18 mSv (33%) when using reduced and 3.44 ± 0.23 mSv (64%) when using extended scan range. The DLP and ED were statistically significantly different between the reduced and extended CT scan range (p < 0.001) in the first and second phases. The individual organ dose was reduced from 8% to 94%. Conclusion: The hybrid SPECT/CT improves the interpretation of nuclear medicine images and also increases the radiation dose to the patient. An adequately defined CT scan range on SPECT/CT imaging, can significantly reduce a patient's ED. Implications for Practice: The research findings showed that knowledge of anatomy, pathology and technology can provide optimising diagnostic procedures and reduce patient ED after SPECT/CT scans. Competing Interests: Conflict of interest statement None (all authors). (Copyright © 2024 The College of Radiographers. Published by Elsevier Ltd. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Computed tomography; Dose length product; Effective dose; Single photon emission computed tomography |
| تواريخ الأحداث: | Date Created: 20240430 Date Completed: 20240516 Latest Revision: 20240516 |
| رمز التحديث: | 20240517 |
| DOI: | 10.1016/j.radi.2024.04.013 |
| PMID: | 38688163 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1532-2831 |
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| DOI: | 10.1016/j.radi.2024.04.013 |