دورية أكاديمية
Multivariate analysis and mathematical modeling of the informativeness of patients cases data in chronic pancreatitis associated with concomitant pathology.
| العنوان: | Multivariate analysis and mathematical modeling of the informativeness of patients cases data in chronic pancreatitis associated with concomitant pathology. |
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| المؤلفون: | Horlenko OM; UZHHOROD NATIONAL UNIVERSITY, UZHHOROD, UKRAINE., Prylypko LB; UZHHOROD NATIONAL UNIVERSITY, UZHHOROD, UKRAINE., Rishko MV; UZHHOROD NATIONAL UNIVERSITY, UZHHOROD, UKRAINE., Beley GM; UZHHOROD NATIONAL UNIVERSITY, UZHHOROD, UKRAINE., Horlenko FV; UZHHOROD NATIONAL UNIVERSITY, UZHHOROD, UKRAINE., Halay BM; UZHHOROD NATIONAL UNIVERSITY, UZHHOROD, UKRAINE., Halay LA; UZHHOROD NATIONAL UNIVERSITY, UZHHOROD, UKRAINE. |
| المصدر: | Wiadomosci lekarskie (Warsaw, Poland : 1960) [Wiad Lek] 2024; Vol. 77 (3), pp. 393-401. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Aluna Publishing Country of Publication: Poland NLM ID: 9705467 Publication Model: Print Cited Medium: Print ISSN: 0043-5147 (Print) Linking ISSN: 00435147 NLM ISO Abbreviation: Wiad Lek Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Konstancin Jeziorna : Aluna Publishing Original Publication: Warszawa : Pánstwowy Zakład Wydawnictw Lekarskich, [1960- |
| مواضيع طبية MeSH: | Multivariate Analysis* , Pancreatitis, Chronic*/blood , Pancreatitis, Chronic*/diagnosis , Pancreatitis, Chronic*/pathology , Hypertension*/blood , Hypertension*/diagnosis , Hypertension*/pathology, Humans ; Adult ; Middle Aged ; Gastrointestinal Diseases/diagnosis |
| مستخلص: | Objective: Aim: To investigate and analyze homeostatic disorders in patients with a combination of Chronic Pancreatitis(CP) and Arterial Hypertension (AH) and to develop correcting ways of the detected changes. Patients and Methods: Materials and Methods: General clinical, laboratory-instrumental examination of 121 patients, who were undergoing inpatient treatment with a diagnosis of Chronic Pancreatitis in combination with Arterial Hypertension of the II stage during 2021-2022. Results: Results: In the majority of cases of patients signs the increasing in IL-1,6 and Cortisol levels were found. A decrease in Ca to the lower limit of the norm was observed (2.18 ± 0.26 mmol/l to the data of control group patients (2.32 ± 0.12 mmol/l, p= 0.01 ), the levels of trace elements Zn and Se were determined within the reference values. The Atherogenic Index was increased 1.8 times and was significantly different from the control group date. During the FE-1 study, a decrease in the level of this indicator was revealed by 151.71±13.91 mg/g of feces, both to the values of reference values and a significant difference to the data of the control group (241.28±29.17 mg/g of feces, p<0 .05). Conclusion: Conclusions: Based on the multivariate linear regression analysis of the obtained data, formulas have been developed that can be used to predict the dynamics of the dependent variable (FE-1, IL-1, Selenium level, Glutathione Peroxidase, blood pressure) according to changes in the studied influencing factors. |
| فهرسة مساهمة: | Keywords: Hypertension; Chronic pancreatitis; associated pathology of the Digestive tract (Non-alcoholic Fatty Liver disease Gastroesophageal Reflux disease); inflammatory response; patient |
| تواريخ الأحداث: | Date Created: 20240501 Date Completed: 20240501 Latest Revision: 20240626 |
| رمز التحديث: | 20240627 |
| DOI: | 10.36740/WLek202403104 |
| PMID: | 38691778 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 0043-5147 |
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| DOI: | 10.36740/WLek202403104 |