دورية أكاديمية
New records on toxic cyanobacteria from Brazil: Exploring their occurrence and geography.
| العنوان: | New records on toxic cyanobacteria from Brazil: Exploring their occurrence and geography. |
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| المؤلفون: | Campos TGV; University of São Paulo, School of Pharmaceutical Sciences, Avenida Prof. Lineu Prestes, 580, Butantã, CEP 05508-900 São Paulo, SP, Brazil., Gama WA; Federal Rural University of Pernambuco, Rua Dom Manuel de Medeiros, s/n, Dois Irmãos, CEP 52171-900, Recife, PE, Brazil., Geraldes V; University of São Paulo, School of Pharmaceutical Sciences, Avenida Prof. Lineu Prestes, 580, Butantã, CEP 05508-900 São Paulo, SP, Brazil; Centre for Nuclear Energy in Agriculture, University of São Paulo, CEP 13418-260, Piracicaba, SP, Brazil., Yoon J; University of São Paulo, School of Pharmaceutical Sciences, Avenida Prof. Lineu Prestes, 580, Butantã, CEP 05508-900 São Paulo, SP, Brazil., Crnkovic CM; University of São Paulo, School of Pharmaceutical Sciences, Avenida Prof. Lineu Prestes, 580, Butantã, CEP 05508-900 São Paulo, SP, Brazil., Pinto E; University of São Paulo, School of Pharmaceutical Sciences, Avenida Prof. Lineu Prestes, 580, Butantã, CEP 05508-900 São Paulo, SP, Brazil; Centre for Nuclear Energy in Agriculture, University of São Paulo, CEP 13418-260, Piracicaba, SP, Brazil., Jacinavicius FR; University of São Paulo, School of Pharmaceutical Sciences, Avenida Prof. Lineu Prestes, 580, Butantã, CEP 05508-900 São Paulo, SP, Brazil; Centre for Nuclear Energy in Agriculture, University of São Paulo, CEP 13418-260, Piracicaba, SP, Brazil. Electronic address: fjacinavicius@gmail.com. |
| المصدر: | The Science of the total environment [Sci Total Environ] 2024 Jun 25; Vol. 931, pp. 172689. Date of Electronic Publication: 2024 Apr 29. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0330500 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1026 (Electronic) Linking ISSN: 00489697 NLM ISO Abbreviation: Sci Total Environ Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Amsterdam, Elsevier. |
| مواضيع طبية MeSH: | Cyanobacteria* , Harmful Algal Bloom* , Environmental Monitoring*/methods , Microcystins*/analysis, Brazil/epidemiology ; Bacterial Toxins/analysis ; Marine Toxins/analysis |
| مستخلص: | Cyanobacterial Harmful Algal Blooms (CyanoHABs) pose a significant threat to communities globally, impacting ecosystems and public health. This study provides an in-depth review of the current state of cyanotoxins and the distribution of CyanoHABs species in Brazil, while also detailing the methods used for their detection. Four hundred and twenty-one incidents were analyzed from 1993 to 2021, compiling cyanotoxin records and toxic CyanoHABs occurrences. The investigation begins with the first detection of microcystins in 1994 and highlights pivotal moments, like the 1996 "Caruaru Syndrome" outbreak. This event encouraged research and updated cyanotoxin-monitoring guidelines. The Brazilian drought period of 2015-2016 exacerbated cyanobacterial growth and saxitoxin levels, coinciding with Zika-related microcephaly. This study delves into methods used for cyanotoxin analysis, including ELISA, bioassays, HPLC, and LC-MS. Additionally, we investigated the toxicity of 37 cyanobacterial strains isolated from various Brazilian environments. Extracts were tested against Artemia salina and analyzed by LC-MS. Results revealed toxicity in extracts from 49 % of cyanobacterial strains. LC-MS results were analyzed using GNPS MS/MS molecular networking for comparing experimental spectra with those of cyanotoxin standards against in-house databases and the existing literature. Our research underscores the variability in cyanotoxin production among species and over time, extending beyond microcystins. LC-MS results, interpreted through the GNPS platform, revealed six cyanotoxin groups in Brazilian strains. Yet, compounds present in 75 % of the toxic extracts remained unidentified. Further research is crucial for fully comprehending the impact of potentially harmful organisms on water quality and public health management strategies. The study highlights the urgent need for continuously monitoring cyanobacteria and the cyanotoxin inclusion of management in public health policies. Competing Interests: Declaration of competing interest The authors declare that there are no conflicts of interest. (Copyright © 2024. Published by Elsevier B.V.) |
| فهرسة مساهمة: | Keywords: Artemia salina; Cyanotoxins; GNPS; LC-MS/MS; Toxicity |
| تواريخ الأحداث: | Date Created: 20240501 Date Completed: 20240521 Latest Revision: 20240521 |
| رمز التحديث: | 20240521 |
| DOI: | 10.1016/j.scitotenv.2024.172689 |
| PMID: | 38692315 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1879-1026 |
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| DOI: | 10.1016/j.scitotenv.2024.172689 |