دورية أكاديمية
أعرض في EDS

Effects of glucagon-like peptide-1 receptor agonists on upper endoscopy in diabetic and nondiabetic patients.

التفاصيل البيبلوغرافية
العنوان: Effects of glucagon-like peptide-1 receptor agonists on upper endoscopy in diabetic and nondiabetic patients.
المؤلفون: Nadeem D; Department of Gastroenterology, Hepatology and Nutrition, Geisinger Medical Center, Danville, Pennsylvania, USA. Electronic address: danialnadeem1@gmail.com., Taye M; Geisinger Commonwealth School of Medicine, Danville, Pennsylvania, USA., Still MD; Geisinger Commonwealth School of Medicine, Danville, Pennsylvania, USA., McShea S; Department of Gastroenterology, Hepatology and Nutrition, Geisinger Medical Center, Danville, Pennsylvania, USA., Satterfield D; Department of Gastroenterology, Hepatology and Nutrition, Geisinger Medical Center, Danville, Pennsylvania, USA., Dove JT; Center for Obesity and Metabolic Research, Geisinger Medical Center, Danville, Pennsylvania, USA., Wood GC; Center for Obesity and Metabolic Research, Geisinger Medical Center, Danville, Pennsylvania, USA., Addissie BD; Department of Gastroenterology, Hepatology and Nutrition, Geisinger Medical Center, Danville, Pennsylvania, USA., Diehl DL; Department of Gastroenterology, Hepatology and Nutrition, Geisinger Medical Center, Danville, Pennsylvania, USA., Johal AS; Department of Gastroenterology, Hepatology and Nutrition, Geisinger Medical Center, Danville, Pennsylvania, USA., Khara HS; Department of Gastroenterology, Hepatology and Nutrition, Geisinger Medical Center, Danville, Pennsylvania, USA., Confer BD; Department of Gastroenterology, Hepatology and Nutrition, Geisinger Medical Center, Danville, Pennsylvania, USA., Still CD; Department of Gastroenterology, Hepatology and Nutrition, Geisinger Medical Center, Danville, Pennsylvania, USA.
المصدر: Gastrointestinal endoscopy [Gastrointest Endosc] 2024 Apr 29. Date of Electronic Publication: 2024 Apr 29.
Publication Model: Ahead of Print
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Mosby Yearbook Country of Publication: United States NLM ID: 0010505 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6779 (Electronic) Linking ISSN: 00165107 NLM ISO Abbreviation: Gastrointest Endosc Subsets: MEDLINE
أسماء مطبوعة: Publication: St Louis, Mo : Mosby Yearbook
Original Publication: Denver.
مستخلص: Background and Aims: Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) promote weight loss by suppressing appetite, enhancing satiety, regulating glucose metabolism, and delaying gastric motility. We sought to determine whether GLP-1RA use could affect medical procedures such as EGD.
Methods: We conducted a retrospective study of 35,183 patients who underwent EGD between 2019 and 2023, 922 of whom were using a GLP-1 RAs. Data were collected regarding demographics, diabetes status, retained gastric contents during EGD, incidence of aborted EGD, and necessity for repeat EGD.
Results: GLP-1 RA use was associated with a 4-fold increase in the retention of gastric contents (P < .0001), 4-fold higher rates of aborted EGD (P < .0001), and twice the likelihood of requiring repeat EGD (P = .0001), even after stratifying for the presence of diabetes.
Conclusions: GLP-1 RA use can lead to delayed gastric emptying, affecting EGD adequacy regardless of the presence of diabetes, and may warrant dose adjustment to improve the safety and efficacy of these procedures.
Competing Interests: Disclosure The following author disclosed financial relationships: C.D. Still: Consultant and speake for Lilly and Novo Nordisk; and Consultant for WW and Twenty30 Health. All other authors disclosed no financial relationships.
(Copyright © 2024 American Society for Gastrointestinal Endoscopy. Published by Elsevier Inc. All rights reserved.)
تواريخ الأحداث: Date Created: 20240501 Latest Revision: 20240808
رمز التحديث: 20240808
DOI: 10.1016/j.gie.2024.04.2900
PMID: 38692518
قاعدة البيانات: MEDLINE
الوصف
تدمد:1097-6779
DOI:10.1016/j.gie.2024.04.2900