دورية أكاديمية
Germ fate determinants protect germ precursor cell division by reducing septin and anillin levels at the cell division plane.
العنوان: | Germ fate determinants protect germ precursor cell division by reducing septin and anillin levels at the cell division plane. |
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المؤلفون: | Connors CQ; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY 10032., Mauro MS; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY 10032., Wiles JT; Department of Biological Sciences, Columbia University, New York, NY 10027., Countryman AD; Department of Biomedical Engineering, Columbia University, New York, NY 10027., Martin SL; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY 10032., Lacroix B; Université Paris Cité, CNRS, Institut Jacques Monod, F-75013 Paris, France.; Université de Montpellier, CNRS, Centre de Recherche en Biologie Cellulaire de Montpellier, UMR 5237 Montpellier, France., Shirasu-Hiza M; Department of Genetics and Development, Columbia University Irving Medical Center, New York, NY 10032., Dumont J; Université Paris Cité, CNRS, Institut Jacques Monod, F-75013 Paris, France., Kasza KE; Department of Mechanical Engineering, Columbia University, New York, NY 10027., Davies TR; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY 10032.; Department of Biosciences, Durham University, Durham DH1 3LE, UK., Canman JC; Department of Pathology and Cell Biology, Columbia University Irving Medical Center, New York, NY 10032. |
المصدر: | Molecular biology of the cell [Mol Biol Cell] 2024 Jul 01; Vol. 35 (7), pp. ar94. Date of Electronic Publication: 2024 May 02. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: American Society for Cell Biology Country of Publication: United States NLM ID: 9201390 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1939-4586 (Electronic) Linking ISSN: 10591524 NLM ISO Abbreviation: Mol Biol Cell Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: Bethesda, MD : American Society for Cell Biology, c1992- |
مواضيع طبية MeSH: | Cytokinesis*/physiology , Caenorhabditis elegans*/metabolism , Caenorhabditis elegans*/embryology , Caenorhabditis elegans Proteins*/metabolism , Caenorhabditis elegans Proteins*/genetics , Septins*/metabolism , Septins*/genetics , Cell Division* , Germ Cells*/metabolism , Germ Cells*/cytology , Actins*/metabolism, Animals ; Contractile Proteins/metabolism ; Actomyosin/metabolism |
مستخلص: | Animal cell cytokinesis, or the physical division of one cell into two, is thought to be driven by constriction of an actomyosin contractile ring at the division plane. The mechanisms underlying cell type-specific differences in cytokinesis remain unknown. Germ cells are totipotent cells that pass genetic information to the next generation. Previously, using formin cyk-1 (ts) mutant Caenorhabditis elegans 4-cell embryos, we found that the P2 germ precursor cell is protected from cytokinesis failure and can divide with greatly reduced F-actin levels at the cell division plane. Here, we identified two canonical germ fate determinants required for P2-specific cytokinetic protection: PIE-1 and POS-1. Neither has been implicated previously in cytokinesis. These germ fate determinants protect P2 cytokinesis by reducing the accumulation of septin UNC-59 and anillin ANI-1 at the division plane, which here act as negative regulators of cytokinesis. These findings may provide insight into the regulation of cytokinesis in other cell types, especially in stem cells with high potency. |
التعليقات: | Update of: bioRxiv. 2023 Nov 17:2023.11.17.566773. doi: 10.1101/2023.11.17.566773. (PMID: 38014027) |
References: | Hum Genet. 2016 Oct;135(10):1199-207. (PMID: 27519304) Cell Rep. 2018 Oct 9;25(2):464-477.e4. (PMID: 30304685) Cell. 2008 Oct 3;135(1):149-60. (PMID: 18854162) Dev Cell. 2018 May 21;45(4):496-511.e6. (PMID: 29787710) Nat Cell Biol. 2015 Jul;17(7):953. (PMID: 26123112) Mol Biol Cell. 2011 Mar 1;22(5):593-605. (PMID: 21209320) Development. 1999 Jan;126(1):1-11. (PMID: 9834181) Nature. 1996 Aug 22;382(6593):710-2. (PMID: 8751440) Dev Cell. 2007 May;12(5):827-35. (PMID: 17488632) Nat Methods. 2018 Nov;15(11):921-923. (PMID: 30377360) PLoS Comput Biol. 2012;8(5):e1002512. (PMID: 22615550) Mol Biol Cell. 2021 Aug 19;32(18):1664-1676. (PMID: 34038147) Dev Biol. 2010 Mar 15;339(2):366-73. (PMID: 20059995) Cytoskeleton (Hoboken). 2024 Mar 8;:. (PMID: 38456577) J Cell Biol. 2005 Oct 24;171(2):267-79. (PMID: 16247027) Crit Rev Clin Lab Sci. 2015;52(4):159-67. (PMID: 26104038) J Comp Neurol. 2009 Mar 20;513(3):249-64. (PMID: 19148892) Am J Hum Genet. 2016 Aug 4;99(2):511-20. (PMID: 27453579) J Cell Biol. 1999 Mar 8;144(5):927-46. (PMID: 10085292) Annu Rev Cell Dev Biol. 2012;28:29-58. (PMID: 22804577) Genes Dev. 1999 Jan 15;13(2):202-12. (PMID: 9925644) Cell Rep. 2023 Sep 26;42(9):113076. (PMID: 37665665) J Cell Biol. 1999 Nov 29;147(5):981-94. (PMID: 10579719) Front Cell Dev Biol. 2022 Nov 24;10:1046617. (PMID: 36506096) Development. 1997 Jun;124(11):2191-201. (PMID: 9187145) Curr Biol. 2012 Feb 7;22(3):197-203. (PMID: 22226749) Mol Cell. 2000 Aug;6(2):445-55. (PMID: 10983990) Nat Genet. 2003 May;34(1):59-64. (PMID: 12669066) J Cell Biol. 2017 Dec 4;216(12):4041-4052. (PMID: 29051266) Cell. 1992 Jul 10;70(1):163-76. (PMID: 1623520) Semin Cell Dev Biol. 2010 Dec;21(9):881-91. (PMID: 20732437) Mol Biol Cell. 2005 Jan;16(1):193-201. (PMID: 15496454) Proc Natl Acad Sci U S A. 2014 Aug 26;111(34):12432-7. (PMID: 25114211) Adv Exp Med Biol. 2013;757:17-39. (PMID: 22872473) ACS Appl Mater Interfaces. 2017 Mar 8;9(9):7929-7940. (PMID: 28221018) Nature. 2003 Aug 7;424(6949):685-9. (PMID: 12894212) Blood. 2013 Sep 26;122(13):2162-6. (PMID: 23940284) Elife. 2018 Jul 20;7:. (PMID: 30028292) Dev Biol. 2012 Mar 15;363(2):388-98. (PMID: 22265679) J Cell Biol. 2000 Aug 7;150(3):539-52. (PMID: 10931866) Sci Rep. 2019 Oct 10;9(1):14647. (PMID: 31601854) Dev Cell. 2016 Aug 22;38(4):430-44. (PMID: 27554860) Nat Rev Mol Cell Biol. 2015 Jul;16(7):406-16. (PMID: 26122616) Genes Dev. 2001 Apr 15;15(8):1031-40. (PMID: 11316796) WormBook. 2014 Dec 30;:1-43. (PMID: 25548889) J Cell Sci. 2015 May 15;128(10):1877-86. (PMID: 25690008) J Cell Sci. 2007 Oct 15;120(Pt 20):3633-9. (PMID: 17895361) J Cell Sci. 2000 Nov;113 Pt 21:3825-37. (PMID: 11034910) Cell. 2006 Apr 7;125(1):85-98. (PMID: 16615892) BMC Dev Biol. 2014 Dec 20;14:46. (PMID: 25527079) J Cell Biol. 2022 Mar 7;221(3):. (PMID: 34994802) Development. 2003 Apr;130(7):1255-65. (PMID: 12588843) Curr Biol. 2017 Mar 20;27(6):860-867. (PMID: 28285996) Am J Hum Genet. 1998 Mar;62(3):533-41. (PMID: 9497258) Cell Mol Life Sci. 2007 Dec;64(23):3044-58. (PMID: 17882379) Curr Opin Cell Biol. 2021 Feb;68:105-112. (PMID: 33188984) J Pathol. 2014 Jul;233(3):247-57. (PMID: 24604753) Nat Commun. 2018 Oct 17;9(1):4308. (PMID: 30333493) J Cell Sci. 1999 Jul;112 ( Pt 14):2323-34. (PMID: 10381388) Development. 2003 Jun;130(11):2495-503. (PMID: 12702662) Dev Cell. 2015 Jul 6;34(1):108-18. (PMID: 26096734) Nat Methods. 2012 Jun 28;9(7):676-82. (PMID: 22743772) Cold Spring Harb Perspect Biol. 2015 Feb 13;7(4):a015834. (PMID: 25680833) J Cell Biol. 1996 Feb;132(3):399-411. (PMID: 8636217) Development. 2023 Jun 15;150(12):. (PMID: 37314175) Elife. 2021 May 18;10:. (PMID: 34003111) Front Cell Dev Biol. 2021 Nov 25;9:793920. (PMID: 34901034) Genetics. 2008 Jan;178(1):235-43. (PMID: 18202370) Hum Genet. 2016 Oct;135(10):1191-7. (PMID: 27503289) EMBO Rep. 2005 Dec;6(12):1163-8. (PMID: 16170304) Dev Cell. 2004 Sep;7(3):413-24. (PMID: 15363415) Dev Biol. 1983 Nov;100(1):64-119. (PMID: 6684600) Development. 2010 Oct;137(19):3337-45. (PMID: 20823070) Cell. 2002 Dec 27;111(7):991-1002. (PMID: 12507426) Curr Biol. 2015 May 4;25(9):1187-94. (PMID: 25866389) Curr Opin Cell Biol. 1996 Feb;8(1):106-19. (PMID: 8791410) Neuron. 2000 Oct;28(1):115-27. (PMID: 11086988) Nucleic Acids Res. 2010 Jul;38(Web Server issue):W332-9. (PMID: 20444868) Ciba Found Symp. 1994;182:282-96; discussion 296-300. (PMID: 7530619) Dev Cell. 2010 Feb 16;18(2):226-36. (PMID: 20159593) Dev Biol. 2006 Apr 1;292(1):244-52. (PMID: 16499902) Curr Opin Genet Dev. 2007 Apr;17(2):157-62. (PMID: 17324569) Cell Death Differ. 2016 May;23(5):801-13. (PMID: 26586574) Dev Cell. 2014 Jul 28;30(2):209-23. (PMID: 25073157) Curr Opin Genet Dev. 2003 Oct;13(5):455-62. (PMID: 14550409) Development. 1997 Feb;124(3):731-9. (PMID: 9043088) Genetics. 2017 Aug;206(4):2007-2039. (PMID: 28576864) Am J Hum Genet. 2016 Aug 4;99(2):501-10. (PMID: 27453578) ACS Biomater Sci Eng. 2019 Aug 12;5(8):3788-3801. (PMID: 33438419) Hum Mol Genet. 2009 Apr 1;18(7):1301-9. (PMID: 19147683) J Clin Invest. 2010 Nov;120(11):3834-42. (PMID: 20921626) Dev Biol. 1998 Aug 15;200(2):212-24. (PMID: 9705228) Genetics. 1974 May;77(1):71-94. (PMID: 4366476) J Pathol. 2012 Jan;226(2):338-51. (PMID: 21984283) J Cell Biol. 2017 May 1;216(5):1371-1386. (PMID: 28400443) MicroPubl Biol. 2019 Dec 20;2019:. (PMID: 32550451) Cytoskeleton (Hoboken). 2019 Jan;76(1):33-44. (PMID: 30171672) Mol Biol Cell. 2012 Oct;23(20):3982-92. (PMID: 22918943) Development. 1994 Aug;120(8):2305-15. (PMID: 7925031) Elife. 2018 Jul 10;7:. (PMID: 29989548) Am J Hum Genet. 2020 Dec 3;107(6):1149-1156. (PMID: 33186543) Gene. 2001 Jan 24;263(1-2):103-12. (PMID: 11223248) J Cell Biol. 2016 Jan 4;212(1):39-49. (PMID: 26728855) MicroPubl Biol. 2021 Aug 04;2021:. (PMID: 34377962) Nature. 1996 Aug 22;382(6593):713-6. (PMID: 8751441) J Hepatol. 2021 Nov;75(5):1177-1191. (PMID: 34228992) J Exp Med. 2007 Sep 3;204(9):2213-24. (PMID: 17724125) G3 (Bethesda). 2018 Dec 10;8(12):3791-3801. (PMID: 30279189) Cell Stem Cell. 2010 Aug 6;7(2):240-8. (PMID: 20682449) Dev Cell. 2019 Mar 25;48(6):864-872.e7. (PMID: 30827898) Cytoskeleton (Hoboken). 2012 Oct;69(10):764-77. (PMID: 22888038) Curr Biol. 2008 Oct 14;18(19):1476-82. (PMID: 18818082) J Mol Cell Cardiol. 1997 Jun;29(6):1541-51. (PMID: 9220340) RNA. 2008 Dec;14(12):2685-97. (PMID: 18952820) Mol Biol Cell. 2000 Sep;11(9):3123-35. (PMID: 10982405) Cereb Cortex. 2020 May 14;30(5):3030-3043. (PMID: 31813992) Dev Cell. 2003 Nov;5(5):723-34. (PMID: 14602073) Cell. 2014 Aug 14;158(4):833-848. (PMID: 25126788) PLoS Biol. 2018 Aug 6;16(8):e2005189. (PMID: 30080857) Cereb Cortex. 2003 Jun;13(6):588-91. (PMID: 12764032) J Cell Physiol. 2002 Jan;190(1):7-20. (PMID: 11807806) Science. 2007 Apr 20;316(5823):392-3. (PMID: 17446385) Blood. 2013 Jun 6;121(23):4791-9. (PMID: 23570799) Mol Biol Cell. 2015 Sep 1;26(17):2963-70. (PMID: 26157168) Bioessays. 1995 May;17(5):405-14. (PMID: 7786286) Cell Motil Cytoskeleton. 2007 Nov;64(11):822-32. (PMID: 17685442) PLoS Genet. 2014 Aug 14;10(8):e1004558. (PMID: 25122120) J Biol Chem. 2016 Feb 12;291(7):3439-54. (PMID: 26670608) Nature. 1996 Aug 1;382(6590):455-8. (PMID: 8684486) Development. 2005 Jun;132(12):2837-48. (PMID: 15930113) Development. 1989 Sep;107(1):1-22. (PMID: 2516798) Front Cell Dev Biol. 2022 Nov 03;10:1001689. (PMID: 36407108) Blood. 2022 Mar 3;139(9):1413-1418. (PMID: 34818416) Genetics. 2022 Apr 4;220(4):. (PMID: 35134929) WormBook. 2005 Jul 28;:1-10. (PMID: 18050414) Development. 2005 Jun;132(12):2849-60. (PMID: 15930114) Nat Methods. 2013 Oct;10(10):1028-34. (PMID: 23995389) Genes Dev. 2008 Nov 15;22(22):3205-16. (PMID: 19056897) Philos Trans R Soc Lond B Biol Sci. 2022 Dec 5;377(1865):20210259. (PMID: 36252219) Microb Cell. 2019 May 22;6(6):295-298. (PMID: 31172014) Genes Dev. 2003 Mar 15;17(6):748-58. (PMID: 12651893) Curr Opin Genet Dev. 2008 Aug;18(4):337-41. (PMID: 18625315) Mol Reprod Dev. 2014 Aug;81(8):679-711. (PMID: 23900765) Dev Neurosci. 2007;29(1-2):113-23. (PMID: 17148954) Front Biosci (Landmark Ed). 2009 Jan 01;14(3):1068-87. (PMID: 19273116) Mol Biol Cell. 2017 Nov 1;28(22):3082-3094. (PMID: 28904204) |
معلومات مُعتمدة: | R01 GM117407 United States GM NIGMS NIH HHS; P40 OD010440 United States OD NIH HHS; R01 AG045842 United States AG NIA NIH HHS; R35 GM138380 United States GM NIGMS NIH HHS; R35 GM127049 United States GM NIGMS NIH HHS |
المشرفين على المادة: | 0 (Caenorhabditis elegans Proteins) EC 3.6.1.- (Septins) 0 (anillin) 0 (Actins) 0 (Contractile Proteins) 9013-26-7 (Actomyosin) |
تواريخ الأحداث: | Date Created: 20240502 Date Completed: 20240606 Latest Revision: 20240714 |
رمز التحديث: | 20240714 |
مُعرف محوري في PubMed: | PMC11244169 |
DOI: | 10.1091/mbc.E24-02-0096-T |
PMID: | 38696255 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1939-4586 |
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DOI: | 10.1091/mbc.E24-02-0096-T |