دورية أكاديمية
A comprehensive review on ethnomedicinal, phytochemical and pharmacological properties of genus Bistorta (L.) scop.
| العنوان: | A comprehensive review on ethnomedicinal, phytochemical and pharmacological properties of genus Bistorta (L.) scop. |
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| المؤلفون: | Javid H; Pant Reproductive Biology, Genetic Diversity, and Phytochemistry Research Laboratory, Department of Botany, University of Kashmir, Srinagar 190006, J&K, India., Shaheen I; Biological Invasion Research Laboratory, Department of Botany, University of Kashmir, Srinagar 190006, J&K, India., Qadir RU; Pant Reproductive Biology, Genetic Diversity, and Phytochemistry Research Laboratory, Department of Botany, University of Kashmir, Srinagar 190006, J&K, India. Electronic address: rouf0629@gmail.com., Magray JA; Pant Reproductive Biology, Genetic Diversity, and Phytochemistry Research Laboratory, Department of Botany, University of Kashmir, Srinagar 190006, J&K, India., Wani BA; Pant Reproductive Biology, Genetic Diversity, and Phytochemistry Research Laboratory, Department of Botany, University of Kashmir, Srinagar 190006, J&K, India., Nawchoo IA; Pant Reproductive Biology, Genetic Diversity, and Phytochemistry Research Laboratory, Department of Botany, University of Kashmir, Srinagar 190006, J&K, India., Gulzar S; Government College for Womens, Maulana Azad Road, Cluster University Srinagar, J&K, India. |
| المصدر: | Fitoterapia [Fitoterapia] 2024 Jul; Vol. 176, pp. 105977. Date of Electronic Publication: 2024 May 01. |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 16930290R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6971 (Electronic) Linking ISSN: 0367326X NLM ISO Abbreviation: Fitoterapia Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 1999- : [Amsterdam] : Elsevier Original Publication: Milano : Inverni & Della Beffa S.p.A. |
| مواضيع طبية MeSH: | Phytochemicals*/pharmacology , Phytochemicals*/chemistry , Phytochemicals*/isolation & purification , Medicine, Traditional*, Humans ; Molecular Structure ; Phytotherapy ; Plants, Medicinal/chemistry ; Ethnopharmacology ; Plant Extracts/pharmacology ; Plant Extracts/chemistry ; Animals |
| مستخلص: | The genus Bistorta comprises about 43 accepted species that are widely used by local people and medicinal practitioners for the treatment of rheumatism, tuberculosis, inflammation, respiratory infection, and other diseases. The objective of this review is to present up-to-date information from the scientific literature about the phytochemistry, pharmacology, and toxicology of Bistorta. At present, there is a lack of a comprehensive review that consolidates the various scientific studies conducted on the genus Bistorta. To address this knowledge gap, a global review has been compiled on the genus Bistorta, which emphasizes ethnomedicinal uses, phytochemistry, and pharmacology. To gather information about Bistorta, relevant keywords were used to search internet databases including Google scholar, PubMed, ResearchGate, Web of Science, Europe PMC, CNKI, and Wiley Online Library. Additionally, published books that provided an overview of existing literature studies were consulted for reference purposes. Chemical structures and formulas of compounds were verified using the PubChem database and drawn using Chem Draw Ultra 6.0. The scientific nomenclature utilized in this review follows The World Flora Online and The Plant of the World Online (PoWo). A comprehensive evaluation of literature sources revealed that the genus Bistorta has been recognized for its ethnomedical properties and has been used in traditional healthcare for several millennia. Chemical analysis has identified various compounds such as phenolics, flavonoids saponins, terpenes, sterols, and coumarins which have been shown to have significant pharmacological effects such as anti-tumor, anti-inflammatory, anti-oxidant anti-rheumatic and anti-microbial properties. The pharmacological research has only partially validated the traditional and local uses of Bistorta species. Further research is required to investigate the mechanisms of the plant's active compounds, as well as its potential therapeutic applications in treating conditions like diabetes and neurodegenerative diseases. Additionally, there is no clinical evidence to provide the health benefits of these plants. To confirm the pharmacological activities, clinical efficacy, and non-toxicity of Bistorta species, more comprehensive and systematic preclinical studies, and clinical trials are needed. Competing Interests: Declaration of competing interest The authors declare that have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (Copyright © 2024 Elsevier B.V. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Biological activities; Bistorta; Ethnobotany; Kashmir Himalaya; Pharmacology; Phytochemicals |
| المشرفين على المادة: | 0 (Phytochemicals) 0 (Plant Extracts) |
| تواريخ الأحداث: | Date Created: 20240502 Date Completed: 20240616 Latest Revision: 20240617 |
| رمز التحديث: | 20240618 |
| DOI: | 10.1016/j.fitote.2024.105977 |
| PMID: | 38697228 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1873-6971 |
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| DOI: | 10.1016/j.fitote.2024.105977 |