دورية أكاديمية
Removal of pharmaceutical compounds and toxicology study in wastewater using Malaysian fungal Ganoderma lucidum.
| العنوان: | Removal of pharmaceutical compounds and toxicology study in wastewater using Malaysian fungal Ganoderma lucidum. |
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| المؤلفون: | Mohd Hanafiah Z; Department of Civil Engineering, Faculty of Engineering and Built Environment, Universiti Kebangsaan Malaysia, 43600, UKM, Bangi, Selangor, Malaysia; Functional Omics and Bioprocess Development Laboratory, Institute of Biological Sciences, Faculty of Science, Universiti Malaya, 50603, Kuala Lumpur, Malaysia., Wan Mohtar WHM; Department of Civil Engineering, Faculty of Engineering and Built Environment, Universiti Kebangsaan Malaysia, 43600, UKM, Bangi, Selangor, Malaysia; Environmental Management Centre, Institute of Climate Change, Universiti Kebangsaan Malaysia, 43600, UKM, Bangi, Selangor, Malaysia. Electronic address: hanna@ukm.edu.my., Wan-Mohtar WAAQI; Functional Omics and Bioprocess Development Laboratory, Institute of Biological Sciences, Faculty of Science, Universiti Malaya, 50603, Kuala Lumpur, Malaysia., Bithi AS; Department of Civil Engineering, Faculty of Engineering and Built Environment, Universiti Kebangsaan Malaysia, 43600, UKM, Bangi, Selangor, Malaysia., Rohani R; Department of Chemical & Process Engineering, Faculty of Engineering and Built Environment, Universiti Kebangsaan Malaysia, 43600, UKM, Bangi, Selangor, Malaysia., Indarto A; Department of Chemical Engineering, Institut Teknologi Bandung, Jl. Ganesha 10, Bandung, 40132, Indonesia., Yaseen ZM; Civil and Environmental Engineering Department, King Fahd University of Petroleum & Minerals, Dhahran, Saudi Arabia., Sharil S; Department of Civil Engineering, Faculty of Engineering and Built Environment, Universiti Kebangsaan Malaysia, 43600, UKM, Bangi, Selangor, Malaysia., Binti Abdul Manan TS; Institute of Tropical Biodiversity and Sustainable Development, Universiti Malaysia Terengganu, 21030, Kuala Nerus, Terengganu, Malaysia. |
| المصدر: | Chemosphere [Chemosphere] 2024 Jun; Vol. 358, pp. 142209. Date of Electronic Publication: 2024 Apr 30. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 0320657 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-1298 (Electronic) Linking ISSN: 00456535 NLM ISO Abbreviation: Chemosphere Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Oxford : Elsevier Science Ltd Original Publication: Oxford, New York, : Pergamon Press. |
| مواضيع طبية MeSH: | Wastewater*/chemistry , Water Pollutants, Chemical*/toxicity , Zebrafish* , Reishi*/metabolism, Animals ; Waste Disposal, Fluid/methods ; Pharmaceutical Preparations/analysis ; Pharmaceutical Preparations/metabolism ; Malaysia ; Sewage/chemistry ; Sewage/microbiology ; Biodegradation, Environmental ; Diclofenac/toxicity |
| مستخلص: | Elevated usage of pharmaceutical products leads to the accumulation of emerging contaminants in sewage. In the current work, Ganoderma lucidum (GL) was used to remove pharmaceutical compounds (PCs), proposed as a tertiary method in sewage treatment plants (STPs). The PCs consisted of a group of painkillers (ketoprofen, diclofenac, and dexamethasone), psychiatrists (carbamazepine, venlafaxine, and citalopram), beta-blockers (atenolol, metoprolol, and propranolol), and anti-hypertensives (losartan and valsartan). The performance of 800 mL of synthetic water, effluent STP, and hospital wastewater (HWW) was evaluated. Parameters, including treatment time, inoculum volume, and mechanical agitation speed, have been tested. The toxicity of the GL after treatment is being studied based on exposure levels to zebrafish embryos (ZFET) and the morphology of the GL has been observed via Field Emission Scanning Electron Microscopy (FESEM). The findings conclude that GL can reduce PCs from <10% to >90%. Diclofenac and valsartan are the highest (>90%) in the synthetic model, while citalopram and propranolol (>80%) are in the real wastewater. GL effectively removed pollutants in 48 h, 1% of the inoculum volume, and 50 rpm. The ZFET showed GL is non-toxic (LC Competing Interests: Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests: Wan Hanna Melini Wan Mohtar reports financial support was provided by Universiti Kebangsaan Malaysia (UKM). (Copyright © 2024. Published by Elsevier Ltd.) |
| فهرسة مساهمة: | Keywords: Ganoderma lucidum; Pharmaceutical compounds; Sewage water treatment; Toxicity |
| تواريخ الأحداث: | Date Created: 20240502 Date Completed: 20240521 Latest Revision: 20240521 |
| رمز التحديث: | 20240521 |
| DOI: | 10.1016/j.chemosphere.2024.142209 |
| PMID: | 38697564 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1879-1298 |
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| DOI: | 10.1016/j.chemosphere.2024.142209 |