دورية أكاديمية
أعرض في EDS

Tensile strength of adhesives in peripheral nerve anastomoses: an in vitro biomechanical evaluation of four different neurorrhaphies.

التفاصيل البيبلوغرافية
العنوان: Tensile strength of adhesives in peripheral nerve anastomoses: an in vitro biomechanical evaluation of four different neurorrhaphies.
المؤلفون: Heitzer M; Department of Oral and Maxillofacial Surgery, University Hospital of RWTH Aachen, Pauwelsstraße 13, 52074, Aachen, Germany. mheitzer@ukaachen.de., Kilic K; Department of Oral and Maxillofacial Surgery, University Hospital of RWTH Aachen, Pauwelsstraße 13, 52074, Aachen, Germany., Merfort R; Department of Orthopedics, Trauma and Reconstructive Surgery, University Hospital of RWTH Aachen, Aachen, Germany., Winnand P; Department of Oral and Maxillofacial Surgery, University Hospital of RWTH Aachen, Pauwelsstraße 13, 52074, Aachen, Germany., Emonts C; Institute of Textile Technology, RWTH Aachen University, Otto-Blumenthal-Straße 1, 52074, Aachen, Germany., Bock A; Department of Oral and Maxillofacial Surgery, University Hospital of RWTH Aachen, Pauwelsstraße 13, 52074, Aachen, Germany., Ooms M; Department of Oral and Maxillofacial Surgery, University Hospital of RWTH Aachen, Pauwelsstraße 13, 52074, Aachen, Germany., Steiner T; Department of Oral and Maxillofacial Surgery, University Hospital of RWTH Aachen, Pauwelsstraße 13, 52074, Aachen, Germany., Hölzle F; Department of Oral and Maxillofacial Surgery, University Hospital of RWTH Aachen, Pauwelsstraße 13, 52074, Aachen, Germany., Modabber A; Department of Oral and Maxillofacial Surgery, University Hospital of RWTH Aachen, Pauwelsstraße 13, 52074, Aachen, Germany.
المصدر: European journal of medical research [Eur J Med Res] 2024 May 03; Vol. 29 (1), pp. 264. Date of Electronic Publication: 2024 May 03.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 9517857 Publication Model: Electronic Cited Medium: Internet ISSN: 2047-783X (Electronic) Linking ISSN: 09492321 NLM ISO Abbreviation: Eur J Med Res Subsets: MEDLINE
أسماء مطبوعة: Publication: Jan. 2012- : London : BioMed Central
Original Publication: Munich, Germany : I. Holzapfel, c1995-
مواضيع طبية MeSH: Tensile Strength* , Anastomosis, Surgical*/methods , Chickens*, Animals ; Biomechanical Phenomena ; Tissue Adhesives/pharmacology ; Fibrin Tissue Adhesive/pharmacology ; Peripheral Nerves/surgery ; Peripheral Nerves/physiology ; Adhesives ; Neurosurgical Procedures/methods
مستخلص: Background: The fundamental prerequisite for prognostically favorable postoperative results of peripheral nerve repair is stable neurorrhaphy without interruption and gap formation.
Methods: This study evaluates 60 neurorrhaphies on femoral chicken nerves in terms of the procedure and the biomechanical properties. Sutured neurorrhaphies (n = 15) served as control and three sutureless adhesive-based nerve repair techniques: Fibrin glue (n = 15), Histoacryl glue (n = 15), and the novel polyurethane adhesive VIVO (n = 15). Tensile and elongation tests of neurorrhaphies were performed on a tensile testing machine at a displacement rate of 20 mm/min until failure. The maximum tensile force and elongation were recorded.
Results: All adhesive-based neurorrhaphies were significant faster in preparation compared to sutured anastomoses (p < 0.001). Neurorrhaphies by sutured (102.8 [cN]; p < 0.001), Histoacryl (91.5 [cN]; p < 0.001) and VIVO (45.47 [cN]; p < 0.05) withstood significant higher longitudinal tensile forces compared to fibrin glue (10.55 [cN]). VIVO, with △L/L 0 of 6.96 [%], showed significantly higher elongation (p < 0.001) compared to neurorrhaphy using fibrin glue.
Conclusion: Within the limitations of an in vitro study the adhesive-based neurorrhaphy technique with VIVO and Histoacryl have the biomechanical potential to offer alternatives to sutured neuroanastomosis because of their stability, and faster handling. Further in vivo studies are required to evaluate functional outcomes and confirm safety.
(© 2024. The Author(s).)
References: Microsurgery. 2010;30(3):218-22. (PMID: 20063379)
Sci Rep. 2017 Apr 12;7:46038. (PMID: 28401914)
J Reconstr Microsurg. 2004 Nov;20(8):645-50. (PMID: 15630661)
J Hand Surg Am. 2021 Feb;46(2):119-125. (PMID: 33261957)
Biomed Tech (Berl). 2011 Apr;56(2):107-13. (PMID: 21366503)
Int J Clin Exp Med. 2015 Nov 15;8(11):20218-26. (PMID: 26884934)
Plast Reconstr Surg. 2011 Jun;127(6):2381-2390. (PMID: 21311390)
Plast Reconstr Surg. 1999 Feb;103(2):730-1. (PMID: 9950569)
Transfusion. 2012 Oct;52(10):2243-55. (PMID: 22612730)
J Reconstr Microsurg. 2008 Jul;24(5):327-32. (PMID: 18597220)
Physiol Res. 1997;46(4):303-6. (PMID: 9728497)
Neural Regen Res. 2015 Jul;10(7):1166-71. (PMID: 26330844)
Ann Plast Surg. 2005 Aug;55(2):188-95. (PMID: 16034252)
Sci Rep. 2021 Jun 30;11(1):13598. (PMID: 34193930)
Head Face Med. 2020 Jul 18;16(1):15. (PMID: 32682430)
Laryngoscope. 1991 Apr;101(4 Pt 1):339-43. (PMID: 1895846)
Head Face Med. 2010 Nov 01;6:25. (PMID: 21040532)
Macromol Biosci. 2022 Apr;22(4):e2100451. (PMID: 35080346)
Eur Surg Res. 2018;59(1-2):48-57. (PMID: 29462813)
Arch Otolaryngol Head Neck Surg. 1990 May;116(5):546-50. (PMID: 2183824)
Clin Exp Ophthalmol. 2000 Dec;28(6):437-42. (PMID: 11202468)
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Oct;104(4):465-72. (PMID: 17507261)
Head Face Med. 2016 Jan 23;12:6. (PMID: 26803587)
Hand Clin. 2012 Nov;28(4):529-40. (PMID: 23101603)
J Biomed Mater Res B Appl Biomater. 2022 Aug;110(8):1922-1931. (PMID: 35293688)
Surg Innov. 2017 Oct;24(5):423-431. (PMID: 28715950)
Chem Rev. 2021 Sep 22;121(18):11336-11384. (PMID: 33507740)
Hand (N Y). 2018 Jan;13(1):45-49. (PMID: 28718327)
Sci Rep. 2020 Dec 10;10(1):21637. (PMID: 33303798)
Neuroreport. 2006 Aug 21;17(12):1245-9. (PMID: 16951563)
J Reconstr Microsurg. 1990 Oct;6(4):331-7. (PMID: 2269954)
Invest Ophthalmol Vis Sci. 1993 Apr;34(5):1722-30. (PMID: 8473112)
Sci Rep. 2018 Jan 12;8(1):620. (PMID: 29330413)
J Funct Biomater. 2023 Jun 22;14(7):. (PMID: 37504828)
Microsurgery. 2022 Jul;42(5):480-489. (PMID: 35670105)
Ann Plast Surg. 2013 Jan;70(1):57-61. (PMID: 22156886)
Hand Clin. 2013 Aug;29(3):371-82. (PMID: 23895717)
Invest Ophthalmol Vis Sci. 2011 Sep 27;52(10):7479-84. (PMID: 21873683)
Scand J Plast Reconstr Surg Hand Surg. 2006;40(2):65-72. (PMID: 16537251)
Ann Anat. 2021 Nov;238:151782. (PMID: 34144156)
Hand Clin. 1996 May;12(2):195-204. (PMID: 8724573)
Ann Plast Surg. 2021 Jan;86(1):103-108. (PMID: 32501840)
Head Face Med. 2016 Nov 4;12(1):29. (PMID: 27809863)
فهرسة مساهمة: Keywords: Anastomosis; Microsurgery; Polyurethanes; Tensile strength; Tissue adhesives
المشرفين على المادة: 0 (Tissue Adhesives)
0 (Fibrin Tissue Adhesive)
0 (Adhesives)
تواريخ الأحداث: Date Created: 20240502 Date Completed: 20240503 Latest Revision: 20240505
رمز التحديث: 20240505
مُعرف محوري في PubMed: PMC11067280
DOI: 10.1186/s40001-024-01858-9
PMID: 38698476
قاعدة البيانات: MEDLINE
الوصف
تدمد:2047-783X
DOI:10.1186/s40001-024-01858-9