دورية أكاديمية
TRBC1 in flow cytometry: Assay development, validation, and reporting considerations.
| العنوان: | TRBC1 in flow cytometry: Assay development, validation, and reporting considerations. |
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| المؤلفون: | Devitt KA; Department of Pathology and Laboratory Medicine, University of Vermont Medical Center, Burlington, Vermont, USA.; Larner College of Medicine at the University of Vermont, Burlington, Vermont, USA., Kern W; Department of Flow Cytometry, MLL Munich Leukemia Laboratory, Munich, Germany., Li W; Department of Pathology and Laboratory Medicine, Children's Mercy Hospital, University of Missouri-Kansas City School of Medicine, Kansas City, Missouri, USA., Wang X; Division of Hematopathology, Vancouver General Hospital, Vancouver, British Columbia, Canada., Wong AJ; Pathology and Laboratory Medicine, Lahey Hospital and Medical Center, Burlington, Massachusetts, USA., Furtado FM; Hematology Department, Sabin Diagnostico e Saude, Brasília, Brazil.; Oncohematology Department, Hospital da Criança de Brasília, Brasília, Brazil., Oak JS; Department of Pathology, Stanford University, Stanford, California, USA., Illingworth A; Department of Flow Cytometry, Dahl-Chase Diagnostic Services/Versant Diagnostics, Bangor, Maine, USA. |
| المصدر: | Cytometry. Part B, Clinical cytometry [Cytometry B Clin Cytom] 2024 May; Vol. 106 (3), pp. 192-202. Date of Electronic Publication: 2024 May 03. |
| نوع المنشور: | Journal Article; Review |
| اللغة: | English |
| بيانات الدورية: | Publisher: Wiley-Liss Country of Publication: United States NLM ID: 101235690 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4957 (Electronic) Linking ISSN: 15524949 NLM ISO Abbreviation: Cytometry B Clin Cytom Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Hoboken, N.J. : Wiley-Liss, c2002- |
| مواضيع طبية MeSH: | Flow Cytometry*/methods , Flow Cytometry*/standards , T-Lymphocytes*/immunology, Humans ; Immunophenotyping/methods ; Biomarkers, Tumor/immunology ; Biomarkers, Tumor/genetics |
| مستخلص: | The assessment of T-cell clonality by flow cytometry has long been suboptimal, relying on aberrant marker expression and/or intensity. The introduction of TRBC1 shows much promise for improving the diagnosis of T-cell neoplasms in the clinical flow laboratory. Most laboratories considering this marker already have existing panels designed for T-cell workups and will be determining how best to incorporate TRBC1. We present this comprehensive summary of TRBC1 and supplemental case examples to familiarize the flow cytometry community with its potential for routine application, provide examples of how to incorporate it into T-cell panels, and signal caution in interpreting the results in certain diagnostic scenarios where appropriate. (© 2024 The Authors. Cytometry Part B: Clinical Cytometry published by Wiley Periodicals LLC on behalf of International Clinical Cytometry Society.) |
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| فهرسة مساهمة: | Keywords: T‐cell; flow cytometry; leukemia; lymphoma; validation |
| المشرفين على المادة: | 0 (Biomarkers, Tumor) |
| تواريخ الأحداث: | Date Created: 20240503 Date Completed: 20240531 Latest Revision: 20240605 |
| رمز التحديث: | 20240606 |
| DOI: | 10.1002/cyto.b.22175 |
| PMID: | 38700195 |
| قاعدة البيانات: | MEDLINE |
| تدمد: | 1552-4957 |
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| DOI: | 10.1002/cyto.b.22175 |