دورية أكاديمية
أعرض في EDS

Serum Vitamin D Level in Overweight Individuals and Its Correlation With the Incidence of Non-alcoholic Fatty Liver Disease.

التفاصيل البيبلوغرافية
العنوان: Serum Vitamin D Level in Overweight Individuals and Its Correlation With the Incidence of Non-alcoholic Fatty Liver Disease.
المؤلفون: Qu YL; Department of Gastroenterology, People's Hospital of Henan University of Chinese Medicine, Henan University of Chinese Medicine, Zhengzhou, Henan Province, China. quyu0828@163.com., Song YH, Sun RR, Ma YJ, Zhang Y
المصدر: Physiological research [Physiol Res] 2024 Apr 30; Vol. 73 (2), pp. 265-271.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Published for the Institute of Physiology of the Czechoslovak Academy of Sciences by Academia, Pub. House of the Academy Country of Publication: Czech Republic NLM ID: 9112413 Publication Model: Print Cited Medium: Internet ISSN: 1802-9973 (Electronic) Linking ISSN: 08628408 NLM ISO Abbreviation: Physiol Res Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Praha : Published for the Institute of Physiology of the Czechoslovak Academy of Sciences by Academia, Pub. House of the Academy
مواضيع طبية MeSH: Vitamin D*/*analogs & derivatives, Non-alcoholic Fatty Liver Disease*/blood , Non-alcoholic Fatty Liver Disease*/epidemiology , Non-alcoholic Fatty Liver Disease*/diagnosis , Vitamin D*/blood , Overweight*/blood , Overweight*/epidemiology , Overweight*/complications, Humans ; Male ; Female ; Middle Aged ; Incidence ; Adult ; Body Mass Index ; Case-Control Studies ; China/epidemiology ; Vitamin D Deficiency/blood ; Vitamin D Deficiency/epidemiology ; Vitamin D Deficiency/diagnosis
مستخلص: In this study, we investigated the serum vitamin D level in overweight individuals and its correlation with the incidence of nonalcoholic fatty liver disease (NAFLD). Between May 2020 and May 2021, the Department of Gastroenterology at the People's Hospital of Henan University of Traditional Chinese Medicine treated a total of 321 outpatients and inpatients with NAFLD, who were included in the NAFLD group, while 245 healthy age- and gender-matched individuals were included in the control group. All the data were collected for the relevant indices, including fasting plasma glucose, total cholesterol, triglyceride, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, alanine transaminase, and 25-hydroxy vitamin D (25[OH]D. The patients with NAFLD were divided into the normal BMI group, the overweight group, and the obese group, according to the body mass index, and the 25(OH)D levels were compared between the different groups. Spearman's correlation analysis was performed to analyze the correlation between the serum 25(OH)D level and NAFLD. Regarding the serum 25 (OH)D level, it was lower in the NAFLD group than in the control group ([18.36 + 1.41] µg/L vs [22.33 + 2.59] µg/L, t = ?5.15, P<0.001), and was lower in the overweight group than in the normal group ([18.09 ± 5.81] µg/L vs [20.60 ± 4.16] µg/L, t = 0.26, P = 0.041). The serum 25(OH)D level was thus negatively correlated with the incidence of NAFLD in overweight individuals (r = 0.625, P<0.05). In conclusion, the level of 25(OH)D decreased in patients with NAFLD with increasing BMI (normal, overweight, obese). Keywords: Nonalcoholic fatty liver disease, Vitamin D.
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المشرفين على المادة: 1406-16-2 (Vitamin D)
A288AR3C9H (25-hydroxyvitamin D)
تواريخ الأحداث: Date Created: 20240506 Date Completed: 20240506 Latest Revision: 20240511
رمز التحديث: 20240511
مُعرف محوري في PubMed: PMC11081187
PMID: 38710056
قاعدة البيانات: MEDLINE
الوصف
تدمد:1802-9973