دورية أكاديمية
Seasonality in Crotalus durissus venom.
العنوان: | Seasonality in Crotalus durissus venom. |
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المؤلفون: | Tasima LJ; Laboratory of Herpetology, Butantan Institute, São Paulo, 05503-900, SP, Brazil; Interunidades Em Biotecnologia, Instituto de Ciências Biomédicas-Instituto de Pesquisas Tecnológicas-Instituto Butantan, Universidade de São Paulo, São Paulo, 05508-900, SP, Brazil., Lima EOV; Laboratory of Herpetology, Butantan Institute, São Paulo, 05503-900, SP, Brazil; Interunidades Em Biotecnologia, Instituto de Ciências Biomédicas-Instituto de Pesquisas Tecnológicas-Instituto Butantan, Universidade de São Paulo, São Paulo, 05508-900, SP, Brazil., Hatakeyama DM; Laboratory of Herpetology, Butantan Institute, São Paulo, 05503-900, SP, Brazil; Interunidades Em Biotecnologia, Instituto de Ciências Biomédicas-Instituto de Pesquisas Tecnológicas-Instituto Butantan, Universidade de São Paulo, São Paulo, 05508-900, SP, Brazil., Vidueiros JP; Laboratory of Herpetology, Butantan Institute, São Paulo, 05503-900, SP, Brazil., Stuginski DR; Laboratory of Herpetology, Butantan Institute, São Paulo, 05503-900, SP, Brazil., Grego KF; Laboratory of Herpetology, Butantan Institute, São Paulo, 05503-900, SP, Brazil., Tanaka-Azevedo AM; Laboratory of Herpetology, Butantan Institute, São Paulo, 05503-900, SP, Brazil; Interunidades Em Biotecnologia, Instituto de Ciências Biomédicas-Instituto de Pesquisas Tecnológicas-Instituto Butantan, Universidade de São Paulo, São Paulo, 05508-900, SP, Brazil. Electronic address: anita.azevedo@butantan.gov.br. |
المصدر: | Toxicon : official journal of the International Society on Toxinology [Toxicon] 2024 Jun; Vol. 244, pp. 107748. Date of Electronic Publication: 2024 May 06. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Pergamon Press Country of Publication: England NLM ID: 1307333 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3150 (Electronic) Linking ISSN: 00410101 NLM ISO Abbreviation: Toxicon Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: Oxford ; New York : Pergamon Press, c1962- |
مواضيع طبية MeSH: | Seasons* , Crotalus* , Crotalid Venoms*/toxicity , Crotalid Venoms*/chemistry, Animals ; Male ; Female ; Brazil ; Chromatography, High Pressure Liquid ; Phospholipases A2 ; Venomous Snakes |
مستخلص: | Rattlesnakes belonging to the genus Crotalus are widely distributed throughout the Americas. In Brazil, symptoms commonly associated with envenomation by Crotalus durissus collilineatus include myalgia, rhabdomyolysis, renal failure, neurotoxicity, and progressive paralysis, which are related to the protein composition of this venom. Snake venom composition exhibits compositional variability that may reflect geographic distribution, age, captivity, diet, sex, and even individual genetics. Although seasonality is also considered a possible source of variation, there are few reports of such variability in snake venom. In this work, venoms of the same eight C. durissus collilineatus were extracted every three months for two years, to analyze seasonal changes in composition and activities. To this end, venom composition was analyzed by protein quantification, SDS-PAGE, and HPLC, and the LAAO, PLA Competing Interests: Declaration of competing interest The authors declare the following financial interests/personal relationships which may be considered as potential competing interests:Anita Mitico Tanaka Azevedo reports financial support was provided by State of Sao Paulo Research Foundation. If there are other authors, they declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (Copyright © 2024 Elsevier Ltd. All rights reserved.) |
فهرسة مساهمة: | Keywords: Enzymatic activity; Intraspecific variability; Sexual variability; Snake venom |
المشرفين على المادة: | 0 (Crotalid Venoms) EC 3.1.1.4 (Phospholipases A2) |
SCR Organism: | Crotalus durissus |
تواريخ الأحداث: | Date Created: 20240506 Date Completed: 20240604 Latest Revision: 20240604 |
رمز التحديث: | 20240605 |
DOI: | 10.1016/j.toxicon.2024.107748 |
PMID: | 38710309 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1879-3150 |
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DOI: | 10.1016/j.toxicon.2024.107748 |