| المؤلفون: |
Woronowicz KC; Department of Orthopaedics, Boston Children's Hospital and Department of Genetics, Harvard Medical School, Boston, MA 02115., Esin EV; AN Severtsov Institute of Ecology and Evolution, RAS; Leninskiy-33, 119071 Moscow, Russian Federation., Markevich GN; Kronotsky Nature Biosphere Reserve; Ryabikova-48, 68400 Yelizovo, Russian Federation., Martinez CS; Department of Biology, Boston College, Chestnut Hill, MA 02467., McMenamin SK; Department of Biology, Boston College, Chestnut Hill, MA 02467., Daane JM; Department of Biology and Biochemistry, University of Houston, Houston, TX 77204., Harris MP; Department of Orthopaedics, Boston Children's Hospital and Department of Genetics, Harvard Medical School, Boston, MA 02115., Shkil FN; AN Severtsov Institute of Ecology and Evolution, RAS; Leninskiy-33, 119071 Moscow, Russian Federation.; NK Koltzov Institute of Developmental Biology, RAS; Vavilova-26, 119334 Moscow, Russian Federation. |
| مستخلص: |
Recent adaptive radiations provide evolutionary case studies, which provide the context to parse the relationship between genomic variation and the origins of distinct phenotypes. Sympatric radiations of the charr complex (genus Salvelinus ) present a trove for phylogenetics as charrs have repeatedly diversified into multiple morphs with distinct feeding specializations. However, species flocks normally comprise only two to three lineages. Dolly Varden charr inhabiting Lake Kronotske represent the most extensive radiation described for the charr genus, containing at least seven lineages, each with defining morphological and ecological traits. Here, we perform the first genome-wide analysis of this species flock to parse the foundations of adaptive change. Our data support distinct, reproductively isolated lineages with little evidence of hybridization. We also find that specific selection on thyroid signaling and craniofacial genes forms a genomic basis for the radiation. Thyroid hormone is further implicated in subsequent lineage partitioning events. These results delineate a clear genetic basis for the diversification of specialized lineages, and highlight the role of developmental mechanisms in shaping the forms generated during adaptive radiation.
Competing Interests: Competing interests No competing interests declared. |
