دورية أكاديمية
Reference Standards for C-Peptide in Korean Population: A Korean Endocrine Hormone Reference Standard Data Center Study.
| العنوان: | Reference Standards for C-Peptide in Korean Population: A Korean Endocrine Hormone Reference Standard Data Center Study. |
|---|---|
| المؤلفون: | Cho J; Department of Laboratory Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea., Cho HC; Department of Internal Medicine, Keimyung University Dongsan Hospital, Keimyung University School of Medicine, Daegu, Korea., Ryu OH; Division of Endocrinology and Metabolism, Department of Internal Medicine, Hallym University Chuncheon Sacred Heart Hospital, College of Medicine, Hallym University, Chuncheon, Korea., Kim HJ; Department of Internal Medicine, Nowon Eulji Medical Center, Eulji University School of Medicine, Seoul, Korea., Kim CG; Korea Research Institute of Standards and Science, Daejeon, Korea., Yun YR; Division of Endocrinology and Metabolism, Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea., Chung CH; Division of Endocrinology and Metabolism, Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.; Research Institute of Metabolism and Inflammation, Yonsei University Wonju College of Medicine, Wonju, Korea. |
| مؤلفون مشاركون: | Task Force Team for Korean Hormone Reference Standards |
| المصدر: | Endocrinology and metabolism (Seoul, Korea) [Endocrinol Metab (Seoul)] 2024 Jun; Vol. 39 (3), pp. 489-499. Date of Electronic Publication: 2024 May 09. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Korean Endocrine Society Country of Publication: Korea (South) NLM ID: 101554139 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2093-5978 (Electronic) Linking ISSN: 2093596X NLM ISO Abbreviation: Endocrinol Metab (Seoul) Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Seoul : Korean Endocrine Society, [2010]- |
| مواضيع طبية MeSH: | C-Peptide*/blood , Blood Glucose*/analysis, Humans ; Republic of Korea ; Female ; Male ; Adult ; Middle Aged ; Glucose Tolerance Test/standards ; Reference Standards ; Reference Values ; Glycated Hemoglobin/analysis ; Young Adult ; Aged ; Biomarkers/blood |
| مستخلص: | Backgruound: The Korean Endocrine Hormone Reference Standard Data Center (KEHRS DC) has created reference standards (RSs) for endocrine hormones since 2020. This study is the first of its kind, wherein the KEHRS DC established RSs for serum Cpeptide levels in a healthy Korean population. Methods: Healthy Korean adults were recruited from May 2021 to September 2023. After excluding participants according to our criteria, serum samples were collected; each participant could then choose between fasting glucose only or fasting glucose plus an oral glucose tolerance test (OGTT). If their sample showed high glucose (≥100 mg/dL) or hemoglobin A1c (HbA1c) (≥5.70%), their C-peptide levels were excluded from analyzing the RSs. Results: A total of 1,532 participants were recruited; however, only the data of 1,050 participants were analyzed after excluding those whose samples showed hyperglycemia or high HbA1c. Post-30-minute OGTT data from 342 subjects and post-120-minute OGTT data from 351 subjects were used. The means±2 standard deviations and expanded uncertainties of fasting, post-30-minute and 120-minute OGTT C-peptide levels were 1.26±0.82 and 0.34-3.18, 4.74±3.57 and 1.14-8.33, and 4.85±3.58 and 1.25-8.34 ng/mL, respectively. Serum C-peptide levels correlated with obesity, serum glucose levels, and HbA1c levels. Conclusion: The RSs for serum C-peptide levels established in this study are expected to be useful in both clinical and related fields. |
| References: | Diabetologia. 2009 Oct;52(10):2218-28. (PMID: 19662378) J Hum Hypertens. 2004 Nov;18(11):789-94. (PMID: 15175632) Ann Lab Med. 2018 Nov;38(6):530-537. (PMID: 30027696) Scand J Clin Lab Invest. 2000 Dec;60(8):687-93. (PMID: 11218151) Chronobiol Int. 2021 Mar;38(3):301-317. (PMID: 33535823) J Clin Lab Anal. 2022 Sep;36(9):e24525. (PMID: 35853089) Endocrinol Metab (Seoul). 2020 Mar;35(1):7-13. (PMID: 32207259) Pediatr Diabetes. 2007 Apr;8(2):53-9. (PMID: 17448127) Endocrinol Metab (Seoul). 2016 Jun;31(2):320-7. (PMID: 27349701) Clin Biochem. 2016 Jan;49(1-2):139-49. (PMID: 26297116) Clin Chim Acta. 2015 Oct 23;450:196-202. (PMID: 26310965) J Clin Endocrinol Metab. 2009 Mar;94(3):907-13. (PMID: 19088162) Diabetes Obes Metab. 2022 Oct;24(10):1912-1926. (PMID: 35676794) Clin Biochem. 2017 May;50(7-8):408-413. (PMID: 27989491) Diabetes Care. 2011 Jan;34 Suppl 1:S62-9. (PMID: 21193628) Front Endocrinol (Lausanne). 2023 Sep 07;14:1256093. (PMID: 37745697) Diabetes. 2020 Oct;69(10):2086-2093. (PMID: 32843567) Endocrinol Metab (Seoul). 2016 Sep;31(3):354-360. (PMID: 27546870) Lancet Diabetes Endocrinol. 2016 Jan;4(1):27-34. (PMID: 26577716) Diabet Med. 2013 Jul;30(7):803-17. (PMID: 23413806) Clin Chem. 2008 Jun;54(6):1023-6. (PMID: 18420730) Diabetes Ther. 2017 Jun;8(3):475-487. (PMID: 28484968) Clin Chem Lab Med. 2020 Jul 28;58(8):1302-1313. (PMID: 32160154) Clin Endocrinol (Oxf). 2018 Feb;88(2):311-317. (PMID: 28949026) |
| معلومات مُعتمدة: | 20016225 Korea Research Institute of Standards and Science |
| فهرسة مساهمة: | Keywords: C-peptide; Diabetes; Korean Endocrine Hormone Reference Standard Data Center; Oral glucose tolerance test; Reference standards |
| المشرفين على المادة: | 0 (C-Peptide) 0 (Blood Glucose) 0 (Glycated Hemoglobin) 0 (Biomarkers) |
| تواريخ الأحداث: | Date Created: 20240509 Date Completed: 20240628 Latest Revision: 20240705 |
| رمز التحديث: | 20240705 |
| مُعرف محوري في PubMed: | PMC11220213 |
| DOI: | 10.3803/EnM.2023.1888 |
| PMID: | 38721635 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2093-5978 |
|---|---|
| DOI: | 10.3803/EnM.2023.1888 |