دورية أكاديمية
Genomic analysis of the first multidrug-resistant ESBL-producing high-risk clonal lineage Klebsiella pneumoniae ST147 isolated from a cat with urinary tract infection.
العنوان: | Genomic analysis of the first multidrug-resistant ESBL-producing high-risk clonal lineage Klebsiella pneumoniae ST147 isolated from a cat with urinary tract infection. |
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المؤلفون: | Sakauchi VTS; Laboratório de Zoonoses Bacterianas, Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, São Paulo, Brazil., Haisi A; Instituto de Biotecnologia, Universidade Estadual Paulista (UNESP), Botucatu, Brazil., Araújo Júnior JP; Instituto de Biotecnologia, Universidade Estadual Paulista (UNESP), Botucatu, Brazil., Ferreira Neto JS; Laboratório de Zoonoses Bacterianas, Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, São Paulo, Brazil., Heinemann MB; Laboratório de Zoonoses Bacterianas, Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, São Paulo, Brazil., Gaeta NC; Laboratório de Zoonoses Bacterianas, Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, São Paulo, Brazil. natalia.gaeta@usp.br.; Curso de Medicina Veterinária, Faculdades Integradas Campos Salles, São Paulo, Brazil. natalia.gaeta@usp.br. |
المصدر: | Veterinary research communications [Vet Res Commun] 2024 Aug; Vol. 48 (4), pp. 2783-2788. Date of Electronic Publication: 2024 May 10. |
نوع المنشور: | Journal Article |
اللغة: | English |
بيانات الدورية: | Publisher: Springer Country of Publication: Switzerland NLM ID: 8100520 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-7446 (Electronic) Linking ISSN: 01657380 NLM ISO Abbreviation: Vet Res Commun Subsets: MEDLINE |
أسماء مطبوعة: | Publication: [Cham] : Springer Original Publication: [Amsterdam] : Elsevier, 1980- |
مواضيع طبية MeSH: | Klebsiella pneumoniae*/genetics , Klebsiella pneumoniae*/drug effects , Klebsiella pneumoniae*/isolation & purification , Klebsiella pneumoniae*/enzymology , Urinary Tract Infections*/veterinary , Urinary Tract Infections*/microbiology , Cat Diseases*/microbiology , Drug Resistance, Multiple, Bacterial*/genetics , Klebsiella Infections*/veterinary , Klebsiella Infections*/microbiology, Animals ; Cats ; beta-Lactamases/genetics ; beta-Lactamases/metabolism ; Anti-Bacterial Agents/pharmacology ; Phylogeny ; Genome, Bacterial ; Whole Genome Sequencing/veterinary |
مستخلص: | Urinary tract infections (UTIs) are pervasive in human and veterinary medicine, notably affecting companion animals. These infections frequently lead to the prescription of antibiotics, contributing to the rise of antimicrobial-resistant bacteria. This escalating concern is underscored by the emergence of a previously undocumented case: a high-risk clone, broad-spectrum cephalosporin-resistant K. pneumoniae ST147 strain, denoted USP-275675, isolated from a cat with UTI. Characterized by a multidrug-resistant (MDR) profile, whole genome sequencing exposed several antimicrobial-resistance genes, notably bla (© 2024. The Author(s), under exclusive licence to Springer Nature B.V.) |
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فهرسة مساهمة: | Keywords: Carbapenemases; Cat; Genomic analysis; One health; Surveillance; Urinary tract infection |
المشرفين على المادة: | EC 3.5.2.6 (beta-Lactamases) 0 (Anti-Bacterial Agents) |
تواريخ الأحداث: | Date Created: 20240510 Date Completed: 20240809 Latest Revision: 20240815 |
رمز التحديث: | 20240815 |
DOI: | 10.1007/s11259-024-10396-y |
PMID: | 38727990 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1573-7446 |
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DOI: | 10.1007/s11259-024-10396-y |