دورية أكاديمية
أعرض في EDS

Unravelling the Link between the Gut Microbiome and Autoimmune Kidney Diseases: A Potential New Therapeutic Approach.

التفاصيل البيبلوغرافية
العنوان: Unravelling the Link between the Gut Microbiome and Autoimmune Kidney Diseases: A Potential New Therapeutic Approach.
المؤلفون: Tan DSY; Department of Medicine, Centre for Inflammatory Diseases, Monash University, Clayton, VIC 3168, Australia., Akelew Y; Department of Medicine, Centre for Inflammatory Diseases, Monash University, Clayton, VIC 3168, Australia., Snelson M; School of Biological Science, Monash University, Clayton, VIC 3168, Australia., Nguyen J; The Alfred Centre, School of Translational Medicine, Monash University, Melbourne, VIC 3004, Australia., O'Sullivan KM; Department of Medicine, Centre for Inflammatory Diseases, Monash University, Clayton, VIC 3168, Australia.
المصدر: International journal of molecular sciences [Int J Mol Sci] 2024 Apr 28; Vol. 25 (9). Date of Electronic Publication: 2024 Apr 28.
نوع المنشور: Journal Article; Review
اللغة: English
بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI, [2000-
مواضيع طبية MeSH: Gastrointestinal Microbiome*/immunology , Autoimmune Diseases*/microbiology , Autoimmune Diseases*/immunology , Autoimmune Diseases*/therapy, Humans ; Animals ; Fatty Acids, Volatile/metabolism ; Kidney Diseases/microbiology ; Kidney Diseases/immunology ; Kidney Diseases/therapy
مستخلص: The gut microbiota and short chain fatty acids (SCFA) have been associated with immune regulation and autoimmune diseases. Autoimmune kidney diseases arise from a loss of tolerance to antigens, often with unclear triggers. In this review, we explore the role of the gut microbiome and how disease, diet, and therapy can alter the gut microbiota consortium. Perturbations in the gut microbiota may systemically induce the translocation of microbiota-derived inflammatory molecules such as liposaccharide (LPS) and other toxins by penetrating the gut epithelial barrier. Once in the blood stream, these pro-inflammatory mediators activate immune cells, which release pro-inflammatory molecules, many of which are antigens in autoimmune diseases. The ratio of gut bacteria Bacteroidetes/Firmicutes is associated with worse outcomes in multiple autoimmune kidney diseases including lupus nephritis, MPO-ANCA vasculitis, and Goodpasture's syndrome. Therapies that enhance SCFA-producing bacteria in the gut have powerful therapeutic potential. Dietary fiber is fermented by gut bacteria which in turn release SCFAs that protect the gut barrier, as well as modulating immune responses towards a tolerogenic anti-inflammatory state. Herein, we describe where the current field of research is and the strategies to harness the gut microbiome as potential therapy.
References: Commun Biol. 2019 Dec 16;2:470. (PMID: 31872075)
Eur J Pharmacol. 2018 Jul 15;831:52-59. (PMID: 29750914)
Lupus. 2014 May;23(6):518-26. (PMID: 24763536)
Gut Microbes. 2021 Jan-Dec;13(1):1979878. (PMID: 34586011)
Nutrients. 2023 May 06;15(9):. (PMID: 37432351)
Am J Respir Cell Mol Biol. 2020 Mar;62(3):364-372. (PMID: 31647878)
Gut Microbes. 2021 Jan-Dec;13(1):1941711. (PMID: 34328058)
Front Med (Lausanne). 2021 Jan 21;7:620102. (PMID: 33553216)
Front Pharmacol. 2020 Jan 31;10:1655. (PMID: 32082158)
Nat Rev Nephrol. 2022 Jul;18(7):466-478. (PMID: 35484394)
Int J Environ Res Public Health. 2022 Nov 29;19(23):. (PMID: 36497987)
J Autoimmun. 2023 Dec;141:103038. (PMID: 37117118)
Nutrients. 2022 Oct 21;14(20):. (PMID: 36297103)
PLoS One. 2014 Jun 12;9(6):e99006. (PMID: 24922509)
BMC Nephrol. 2022 Nov 7;23(1):358. (PMID: 36344919)
Immunol Invest. 2016;45(3):205-22. (PMID: 27018846)
Gut Microbes. 2021 Jan-Dec;13(1):1968257. (PMID: 34494943)
Adv Nutr. 2018 Jan 1;9(1):21-29. (PMID: 29438462)
Nephrol Dial Transplant. 2019 May 1;34(5):783-794. (PMID: 30085297)
Oncol Lett. 2018 Oct;16(4):4439-4447. (PMID: 30214578)
Front Cell Infect Microbiol. 2020 Oct 20;10:557368. (PMID: 33194798)
Kidney360. 2021 Jun 9;2(8):1261-1274. (PMID: 35369657)
Front Med (Lausanne). 2022 Dec 02;9:1068567. (PMID: 36530877)
Sci Rep. 2019 Jan 24;9(1):742. (PMID: 30679586)
PLoS One. 2014 Nov 20;9(11):e113054. (PMID: 25411968)
Clin J Am Soc Nephrol. 2014 Dec 5;9(12):2104-10. (PMID: 25280496)
PLoS One. 2016 Sep 22;11(9):e0163750. (PMID: 27658303)
Front Immunol. 2021 Nov 09;12:771619. (PMID: 34858429)
Cells. 2020 Dec 01;9(12):. (PMID: 33271820)
Front Immunol. 2021 Sep 03;12:668974. (PMID: 34539623)
J Nutr Biochem. 2011 Sep;22(9):849-55. (PMID: 21167700)
Lancet. 1999 May 1;353(9163):1509-15. (PMID: 10232333)
Ther Clin Risk Manag. 2010 Jun 24;6:253-64. (PMID: 20596502)
J Clin Endocrinol Metab. 2020 Apr 1;105(4):. (PMID: 31863667)
Sci Adv. 2021 Mar 31;7(14):. (PMID: 33789895)
Am J Nephrol. 2023;54(11-12):451-470. (PMID: 37793354)
Circulation. 2020 Apr 28;141(17):1393-1403. (PMID: 32093510)
Dis Model Mech. 2015 Jan;8(1):1-16. (PMID: 25561744)
Microbiome. 2017 Aug 1;5(1):87. (PMID: 28760163)
Nat Med. 2014 Feb;20(2):159-66. (PMID: 24390308)
J Biol Chem. 2003 Jul 11;278(28):25481-9. (PMID: 12711604)
J Hum Hypertens. 2021 Feb;35(2):162-169. (PMID: 32733062)
Microbiome. 2019 Jun 13;7(1):91. (PMID: 31196177)
Front Nutr. 2022 Sep 16;9:959941. (PMID: 36185680)
J R Soc Med. 1999 Sep;92(9):456-61. (PMID: 10645294)
Toxins (Basel). 2021 Mar 19;13(3):. (PMID: 33808581)
Nat Rev Cardiol. 2018 Jan;15(1):20-32. (PMID: 28836619)
Microbiome. 2017 Feb 1;5(1):14. (PMID: 28143587)
Nature. 2012 Jul 5;487(7405):104-8. (PMID: 22722865)
Physiol Rep. 2020 Oct;8(19):e14610. (PMID: 33038060)
Int J Mol Sci. 2022 Jul 27;23(15):. (PMID: 35955407)
Nephron Clin Pract. 2011;119(2):c97-c104. (PMID: 21677444)
Sci Rep. 2019 Jun 10;9(1):8379. (PMID: 31182740)
Eur J Clin Nutr. 2021 Sep;75(9):1389-1397. (PMID: 33531632)
Biochem Pharmacol. 2017 Jun 15;134:114-126. (PMID: 27641814)
Kidney Int. 2012 Feb;81(3):300-6. (PMID: 22012132)
Kidney Int. 2010 Dec;78(12):1263-74. (PMID: 20844472)
Pharmacol Res. 2013 Mar;69(1):52-60. (PMID: 23147033)
Ann Rheum Dis. 2021 Nov;80(11):e177. (PMID: 31732515)
Hum Vaccin Immunother. 2021 Mar 4;17(3):897-903. (PMID: 32873124)
JCI Insight. 2019 Jun 4;5:. (PMID: 31162138)
Front Endocrinol (Lausanne). 2013 Jan 08;3:181. (PMID: 23316186)
Microbiome. 2022 Jan 19;10(1):9. (PMID: 35045871)
Nature. 2006 Dec 21;444(7122):1022-3. (PMID: 17183309)
Microorganisms. 2020 Nov 01;8(11):. (PMID: 33139627)
Cell Physiol Biochem. 2018;49(1):190-205. (PMID: 30138914)
Microorganisms. 2019 Jan 10;7(1):. (PMID: 30634578)
Nat Rev Dis Primers. 2020 Aug 27;6(1):71. (PMID: 32855422)
J Physiol. 2004 Jun 15;557(Pt 3):719-31. (PMID: 15090606)
Inflamm Allergy Drug Targets. 2009 Jul;8(3):191-201. (PMID: 19601879)
J Am Soc Nephrol. 2013 Mar;24(4):573-85. (PMID: 23393320)
J Am Soc Nephrol. 2006 Jul;17(7):1940-9. (PMID: 16769746)
Med Sci Monit. 2019 Feb 08;25:1061-1070. (PMID: 30733429)
Nature. 2014 Jan 23;505(7484):559-63. (PMID: 24336217)
Nature. 2013 Dec 19;504(7480):451-5. (PMID: 24226773)
EBioMedicine. 2021 Apr;66:103293. (PMID: 33813134)
Rheumatology (Oxford). 2017 Nov 1;56(11):1962-1969. (PMID: 28968886)
Proc Natl Acad Sci U S A. 2016 Dec 13;113(50):E8141-E8150. (PMID: 27911839)
Nat Rev Gastroenterol Hepatol. 2016 Sep;13(9):508-16. (PMID: 27329806)
PLoS One. 2023 Feb 3;18(2):e0280850. (PMID: 36735734)
Cells. 2019 Jul 15;8(7):. (PMID: 31311206)
J Am Soc Nephrol. 1996 Jan;7(1):33-9. (PMID: 8808107)
Front Pediatr. 2022 Jul 14;10:943267. (PMID: 35911834)
Front Immunol. 2023 Apr 28;14:1190177. (PMID: 37187738)
Science. 2018 Mar 9;359(6380):1156-1161. (PMID: 29590047)
J Am Soc Nephrol. 2019 Oct;30(10):2017-2026. (PMID: 31444275)
J Immunol Res. 2021 May 15;2021:5516035. (PMID: 34095319)
Ann Rheum Dis. 2019 Jul;78(7):947-956. (PMID: 30782585)
Am J Clin Nutr. 1979 Oct;32(10):2094-101. (PMID: 484528)
Biomolecules. 2019 Jan 18;9(1):. (PMID: 30669408)
J Atheroscler Thromb. 2017 Jul 1;24(7):660-672. (PMID: 28552897)
Exp Mol Med. 2020 Mar;52(3):423-437. (PMID: 32123288)
Int Immunol. 2015 Jan;27(1):11-20. (PMID: 25087232)
J Extracell Vesicles. 2021 Nov;10(13):e12161. (PMID: 34738337)
Int J Mol Sci. 2021 Dec 06;22(23):. (PMID: 34884969)
Sci Transl Med. 2018 Oct 24;10(464):. (PMID: 30355800)
J Mol Biol. 2006 Jun 23;359(5):1400-9. (PMID: 16725153)
Clin Immunol. 2024 Feb;259:109903. (PMID: 38218211)
J Am Soc Nephrol. 2020 Jun;31(6):1267-1281. (PMID: 32358041)
Biochem Biophys Res Commun. 2017 Apr 29;486(2):499-505. (PMID: 28322790)
Gut Microbes. 2021 Jan-Dec;13(1):1926842. (PMID: 34275431)
Front Pediatr. 2020 Oct 15;8:544460. (PMID: 33178650)
Nutr Res. 2008 May;28(5):321-8. (PMID: 19083427)
PLoS One. 2013 May 01;8(5):e62578. (PMID: 23658749)
Mucosal Immunol. 2015 Jan;8(1):80-93. (PMID: 24917457)
J Autoimmun. 2021 Mar;118:102593. (PMID: 33508637)
Int J Neuropsychopharmacol. 2016 Aug 12;19(8):. (PMID: 26912607)
Nutrients. 2023 Jun 29;15(13):. (PMID: 37447285)
Nutrients. 2020 May 19;12(5):. (PMID: 32438689)
J Ren Nutr. 2019 Sep;29(5):386-393. (PMID: 30982743)
Mod Pathol. 2019 Jul;32(8):1147-1157. (PMID: 30936425)
Infect Immun. 2021 Aug 16;89(9):e0018821. (PMID: 34097474)
Microbiol Spectr. 2021 Dec 22;9(3):e0065021. (PMID: 34756061)
Nephrology (Carlton). 2009 Feb;14(1):42-8. (PMID: 19335843)
Sci Rep. 2020 Sep 3;10(1):14525. (PMID: 32884012)
Inflammation. 2012 Oct;35(5):1676-84. (PMID: 22669487)
J Immunol. 2016 Mar 1;196(5):2388-400. (PMID: 26819206)
Am J Physiol Renal Physiol. 2018 Nov 1;315(5):F1283-F1294. (PMID: 29923769)
Adv Sci (Weinh). 2022 Oct;9(28):e2201581. (PMID: 35975460)
Nature. 2011 Oct 26;479(7374):538-41. (PMID: 22031325)
Proc Natl Acad Sci U S A. 2010 Aug 17;107(33):14691-6. (PMID: 20679230)
Front Microbiol. 2018 Nov 30;9:2897. (PMID: 30555441)
Annu Rev Pathol. 2020 Jan 24;15:287-313. (PMID: 31622560)
Front Cell Infect Microbiol. 2022 Nov 11;12:962216. (PMID: 36439225)
J Transl Med. 2022 Dec 14;20(1):599. (PMID: 36517799)
Nephrol Dial Transplant. 2022 Nov 23;37(12):2303-2306. (PMID: 36155806)
Nat Immunol. 2017 May;18(5):552-562. (PMID: 28346408)
Front Pediatr. 2022 Jan 07;9:800677. (PMID: 35071141)
Adv Nutr. 2020 Jul 1;11(4):1002-1015. (PMID: 32191264)
Adv Nutr. 2019 Mar 1;10(2):303-320. (PMID: 30668615)
Nutrients. 2022 Jun 17;14(12):. (PMID: 35745257)
Arthritis Rheum. 2005 Jan;52(1):262-8. (PMID: 15641078)
Appl Environ Microbiol. 2016 Sep 16;82(19):5850-9. (PMID: 27451450)
PLoS One. 2013 Oct 24;8(10):e76520. (PMID: 24204633)
Gut. 2020 Dec;69(12):2131-2142. (PMID: 32241904)
Front Immunol. 2021 Mar 15;12:635188. (PMID: 33790907)
BMJ. 2018 Jan 8;360:j5145. (PMID: 29311119)
Discov Med. 2015 Feb;19(103):117-25. (PMID: 25725226)
Front Immunol. 2021 Jul 15;12:686501. (PMID: 34335588)
Front Endocrinol (Lausanne). 2019 Aug 27;10:585. (PMID: 31507535)
J Autoimmun. 2015 May;59:8-18. (PMID: 25841937)
Science. 2013 Nov 22;342(6161):971-6. (PMID: 24264990)
Autoimmun Rev. 2014 Jul;13(7):723-9. (PMID: 24657897)
Nat Rev Dis Primers. 2020 Jan 23;6(1):7. (PMID: 31974366)
Int J Mol Sci. 2019 Jun 11;20(11):. (PMID: 31212641)
Hemodial Int. 2019 Jul;23(3):343-347. (PMID: 30924310)
Clin Kidney J. 2021 Sep 14;15(2):213-225. (PMID: 35145637)
J Cell Mol Med. 2019 Feb;23(2):731-739. (PMID: 30585399)
Front Pediatr. 2024 Feb 12;12:1356529. (PMID: 38410769)
N Engl J Med. 1997 Nov 20;337(21):1512-23. (PMID: 9366584)
Sci Rep. 2016 Nov 16;6:37252. (PMID: 27849031)
Int Immunopharmacol. 2020 Dec;89(Pt B):107085. (PMID: 33068859)
Sci Rep. 2022 Jan 7;12(1):152. (PMID: 34996983)
Am J Clin Nutr. 2022 Nov;116(5):1354-1367. (PMID: 36084000)
Sci Transl Med. 2009 Nov 11;1(6):6ra14. (PMID: 20368178)
Nature. 2011 May 12;473(7346):174-80. (PMID: 21508958)
Immunity. 2019 Nov 19;51(5):794-811. (PMID: 31747581)
Nephrology (Carlton). 2008 Jul;13 Suppl 2:S24-36. (PMID: 18713121)
Gastroenterology. 2004 Aug;127(2):412-21. (PMID: 15300573)
Rheum Dis Clin North Am. 2010 Aug;36(3):439-46. (PMID: 20688242)
Cell. 2016 Jun 2;165(6):1332-1345. (PMID: 27259147)
Mol Ecol. 2013 Apr;22(7):1904-16. (PMID: 23398547)
Front Immunol. 2019 Mar 11;10:277. (PMID: 30915065)
Exp Mol Med. 2020 Sep;52(9):1383-1396. (PMID: 32908211)
J Am Soc Nephrol. 2007 Jul;18(7):2180-8. (PMID: 17582159)
PLoS One. 2011;6(6):e21205. (PMID: 21698257)
J Transl Med. 2023 Oct 19;21(1):740. (PMID: 37858192)
PLoS One. 2015 Mar 11;10(3):e0120411. (PMID: 25760949)
Am J Physiol Renal Physiol. 2023 Sep 1;325(3):F345-F362. (PMID: 37440367)
Comp Biochem Physiol A Mol Integr Physiol. 2004 Aug;138(4):475-83. (PMID: 15369837)
Front Pharmacol. 2022 Jan 24;13:783679. (PMID: 35140612)
J Appl Microbiol. 2013 May;114(5):1516-28. (PMID: 23383759)
Am J Pathol. 2010 Nov;177(5):2234-44. (PMID: 20847283)
CEN Case Rep. 2021 May;10(2):261-264. (PMID: 33387212)
Redox Biol. 2018 Jun;16:21-31. (PMID: 29475132)
Gut Microbes. 2022 Jan-Dec;14(1):2134689. (PMID: 36242585)
Blood. 2019 May 16;133(20):2168-2177. (PMID: 30898860)
Nat Rev Rheumatol. 2014 Aug;10(8):463-73. (PMID: 25003769)
Aliment Pharmacol Ther. 2018 Jul;48(1):15-34. (PMID: 29722430)
Blood. 2005 Sep 15;106(6):2050-8. (PMID: 15933057)
Nutr Rev. 2009 Apr;67(4):188-205. (PMID: 19335713)
Front Immunol. 2021 Oct 12;12:694787. (PMID: 34712223)
Am J Physiol Lung Cell Mol Physiol. 2019 Jan 1;316(1):L157-L174. (PMID: 30407866)
Nat Commun. 2019 Feb 15;10(1):760. (PMID: 30770822)
J Am Soc Nephrol. 2006 Aug;17(8):2264-74. (PMID: 16825335)
Biochimie. 2023 Jul;210:71-81. (PMID: 36693616)
Curr Opin Immunol. 2011 Aug;23(4):473-80. (PMID: 21856139)
PLoS One. 2014 Jan 14;9(1):e83644. (PMID: 24454707)
Rev Med Interne. 2020 Jan;41(1):14-20. (PMID: 31776042)
Nat Immunol. 2021 May;22(5):560-570. (PMID: 33753940)
Sci Transl Med. 2017 Nov 15;9(416):. (PMID: 29141885)
Blood. 1990 Jun 1;75(11):2263-4. (PMID: 2189509)
Cell Rep. 2022 May 10;39(6):110783. (PMID: 35545042)
فهرسة مساهمة: Keywords: ANCA; SCFA; autoimmunity; diet therapy; glomerulonephritis; gut microbiota; immune responses; kidney disease; vasculitis
المشرفين على المادة: 0 (Fatty Acids, Volatile)
تواريخ الأحداث: Date Created: 20240511 Date Completed: 20240511 Latest Revision: 20240514
رمز التحديث: 20240514
مُعرف محوري في PubMed: PMC11084259
DOI: 10.3390/ijms25094817
PMID: 38732038
قاعدة البيانات: MEDLINE
الوصف
تدمد:1422-0067
DOI:10.3390/ijms25094817