دورية أكاديمية
Systematic review and meta-analysis of Biodegradable Temporizing Matrix application for complex wound reconstruction.
| العنوان: | Systematic review and meta-analysis of Biodegradable Temporizing Matrix application for complex wound reconstruction. |
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| المؤلفون: | Grande PK; University of Tennessee Health Science Center College of Medicine, Memphis, TN, USA., Hill D; Regional One Health, Pharmacy Department, Memphis, TN, USA., McElfresh J; University of Tennessee Health Science Library, Memphis, TN, USA., Velamuri R; Division of Plastic Surgery, University of Tennessee Health Science Center, Memphis, TN, USA., Liu X; Division of Plastic Surgery, University of Tennessee Health Science Center, Memphis, TN, USA. |
| المصدر: | Journal of burn care & research : official publication of the American Burn Association [J Burn Care Res] 2024 May 11. Date of Electronic Publication: 2024 May 11. |
| Publication Model: | Ahead of Print |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Oxford University Press Country of Publication: England NLM ID: 101262774 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-0488 (Electronic) Linking ISSN: 1559047X NLM ISO Abbreviation: J Burn Care Res Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: 2018- : Oxford : Oxford University Press Original Publication: Hagerstown, MD : Lippincott Williams & Wilkins, c2006- |
| مستخلص: | Biodegradable Temporizing Matrix (BTM) is a synthetic dermal template recently developed to reconstruct complex wounds. Current literature describes BTM outcomes in the presence of infection and other comorbidities but are limited by small sample sizes. The purpose of this systemic review and meta-analysis was to determine current breadth and success of BTM use for complex wound closure. Databases were searched to identify previously published studies describing BTM use in human wounds. Studies were excluded if conducted in vitro, using non-human animals, or for procedures irrelevant to wound care. Twenty-four studies met inclusion criteria, representing 202 patients. The most common injury treated with BTM was burns (68 cases, 33.7%) followed by acute surgical wounds (59 cases, 29.2%). The large majority of patients did not experience any post-operative infections (76.6%). Infected wounds were associated with a 7.5-day delay from BTM to grafting. Univariate regression analyses showed a negative association between time to BTM implantation and age, exposed muscle, and exposed tendon (p < 0.001). Ninety-two percent of patients received BTM implantation less than 2 weeks from admission. Eighty-four percent of patients had a greater than 95% BTM take. The median time to STSG was 34 days, and 92% of patients experienced a greater than 95% STSG survival. To our knowledge, this is the first reported systemic review on the application of BTM for wound reconstruction. According to the published data, BTM is versatile dermal template for complex wounds coverage with low risk of infection, high template take rate, and excellent autograft survival. (© The Author(s) 2024. Published by Oxford University Press on behalf of the American Burn Association. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com.) |
| فهرسة مساهمة: | Keywords: biodegradable temporizing matrix; complex wound; polyurethane matrix; skin substitute |
| تواريخ الأحداث: | Date Created: 20240511 Latest Revision: 20240511 |
| رمز التحديث: | 20240512 |
| DOI: | 10.1093/jbcr/irae081 |
| PMID: | 38733573 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1559-0488 |
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| DOI: | 10.1093/jbcr/irae081 |