دورية أكاديمية
Reserve, resilience and maintenance of episodic memory and other cognitive functions in aging.
| العنوان: | Reserve, resilience and maintenance of episodic memory and other cognitive functions in aging. |
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| المؤلفون: | Schwarz C; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland; Department of Neurology, University Medicine Greifswald, Greifswald, Germany., Franz CE; Department of Psychiatry and Center for Behavioral Genetics of Aging, University of California, San Diego, La Jolla, CA, USA., Kremen WS; Department of Psychiatry and Center for Behavioral Genetics of Aging, University of California, San Diego, La Jolla, CA, USA., Vuoksimaa E; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland; Department of Psychiatry and Center for Behavioral Genetics of Aging, University of California, San Diego, La Jolla, CA, USA. Electronic address: eero.vuoksimaa@helsinki.fi. |
| المصدر: | Neurobiology of aging [Neurobiol Aging] 2024 Aug; Vol. 140, pp. 60-69. Date of Electronic Publication: 2024 May 01. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: United States NLM ID: 8100437 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1558-1497 (Electronic) Linking ISSN: 01974580 NLM ISO Abbreviation: Neurobiol Aging Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: New York : Elsevier Original Publication: Fayetteville, N.Y. : Ankho International. |
| مواضيع طبية MeSH: | Memory, Episodic* , Cognitive Reserve*/physiology , Aging*/psychology , Aging*/physiology , Cognition*/physiology , Magnetic Resonance Imaging* , Brain*/physiology , Brain*/diagnostic imaging, Humans ; Middle Aged ; Male ; Aged ; Young Adult ; Cognitive Aging/physiology ; Cognitive Aging/psychology ; Executive Function/physiology ; Adult ; Female ; Dementia/psychology |
| مستخلص: | We tested if cognitive and brain reserve and maintenance explain individual differences in episodic memory and other cognitive domains from late middle to early older adulthood. We used The Vietnam Era Twin Study of Aging data (n=1604 men) with episodic memory measured at mean ages of 56, 62 and 68 years, and magnetic resonance imaging data for a subsample of participants (n=321). Cognitive reserve -young adult general cognitive ability at a mean age of 20 years and, to a lesser degree, educational attainment- was positively related to episodic memory performance at each assessment, but not to memory change. We found no evidence for the associations of brain reserve or brain maintenance on memory change. Results were highly similar when looking at processing speed, executive function and verbal fluency. In conclusion, higher young adult cognitive reserve was related to better episodic memory in midlife and older adulthood, but it did not confer better cognitive maintenance with respect to memory. This supports the importance of early cognitive development in dementia prevention. Competing Interests: Declaration of Competing Interest The authors have no actual or potential conflicts of interest. (Copyright © 2024 The Authors. Published by Elsevier Inc. All rights reserved.) |
| معلومات مُعتمدة: | R24 AG061421 United States AG NIA NIH HHS |
| فهرسة مساهمة: | Keywords: Cortical thickness; educational attainment; general cognitive ability; surface area |
| تواريخ الأحداث: | Date Created: 20240511 Date Completed: 20240610 Latest Revision: 20240810 |
| رمز التحديث: | 20240812 |
| DOI: | 10.1016/j.neurobiolaging.2024.04.011 |
| PMID: | 38733869 |
| قاعدة البيانات: | MEDLINE |
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Full Text Finder | تدمد: | 1558-1497 |
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| DOI: | 10.1016/j.neurobiolaging.2024.04.011 |