دورية أكاديمية
Self-Assembly Reinforced Alginate Fibers for Enhanced Strength, Toughness, and Bone Regeneration.
| العنوان: | Self-Assembly Reinforced Alginate Fibers for Enhanced Strength, Toughness, and Bone Regeneration. |
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| المؤلفون: | Cui M; State Key Laboratory of Bio-Fibers and Eco-textiles, College of Materials Science and Engineering, Shandong Collaborative Innovation Center of Marine Biobased Fibers and Ecological Textiles, Qingdao University, Qingdao 266071, P. R. China., Liu S; Joint Laboratory of Opto-Functional Theranostics in Medicine and Chemistry, The First Hospital of Jilin University, Changchun 130012, P. R. China., Xie X; State Key Laboratory of Bio-Fibers and Eco-textiles, College of Materials Science and Engineering, Shandong Collaborative Innovation Center of Marine Biobased Fibers and Ecological Textiles, Qingdao University, Qingdao 266071, P. R. China., Yang J; State Key Laboratory of Bio-Fibers and Eco-textiles, College of Materials Science and Engineering, Shandong Collaborative Innovation Center of Marine Biobased Fibers and Ecological Textiles, Qingdao University, Qingdao 266071, P. R. China., Wang T; State Key Laboratory of Bio-Fibers and Eco-textiles, College of Materials Science and Engineering, Shandong Collaborative Innovation Center of Marine Biobased Fibers and Ecological Textiles, Qingdao University, Qingdao 266071, P. R. China., Jiao Y; State Key Laboratory of Bio-Fibers and Eco-textiles, College of Materials Science and Engineering, Shandong Collaborative Innovation Center of Marine Biobased Fibers and Ecological Textiles, Qingdao University, Qingdao 266071, P. R. China., Lin M; State Key Laboratory of Bio-Fibers and Eco-textiles, College of Materials Science and Engineering, Shandong Collaborative Innovation Center of Marine Biobased Fibers and Ecological Textiles, Qingdao University, Qingdao 266071, P. R. China., Sui K; State Key Laboratory of Bio-Fibers and Eco-textiles, College of Materials Science and Engineering, Shandong Collaborative Innovation Center of Marine Biobased Fibers and Ecological Textiles, Qingdao University, Qingdao 266071, P. R. China. |
| المصدر: | Biomacromolecules [Biomacromolecules] 2024 Jun 10; Vol. 25 (6), pp. 3475-3485. Date of Electronic Publication: 2024 May 13. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 100892849 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1526-4602 (Electronic) Linking ISSN: 15257797 NLM ISO Abbreviation: Biomacromolecules Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Washington, DC : American Chemical Society, c2000- |
| مواضيع طبية MeSH: | Alginates*/chemistry , Bone Regeneration*/drug effects , Tensile Strength*, Animals ; Biocompatible Materials/chemistry ; Glucuronic Acid/chemistry ; Materials Testing ; Hexuronic Acids/chemistry ; Tissue Scaffolds/chemistry |
| مستخلص: | Material reinforcement commonly exists in a contradiction between strength and toughness enhancement. Herein, a reinforced strategy through self-assembly is proposed for alginate fibers. Sodium alginate (SA) microstructures with regulated secondary structures are assembled in acidic and ethanol as reinforcing units for alginate fibers. Acidity increases the flexibility of the helix and contributes to enhanced extendibility. Ethanol is responsible for formation of a stiff β-sheet, which enhances the modulus and strength. The structurally engineered SA assembly exhibits robust mechanical compatibility, and thus reinforced alginate fibers possess an improved tensile strength of 2.1 times, a prolonged elongation of 1.5 times, and an enhanced toughness of 3.0 times compared with SA fibers without reinforcement. The reinforcement through self-assembly provides an understanding of strengthening and toughening mechanism based on secondary structures. Due to a similar modulus with bones, reinforced alginate fibers exhibit good efficacy in accelerating bone regeneration in vivo. |
| المشرفين على المادة: | 0 (Alginates) 0 (Biocompatible Materials) 8A5D83Q4RW (Glucuronic Acid) 0 (Hexuronic Acids) |
| تواريخ الأحداث: | Date Created: 20240514 Date Completed: 20240610 Latest Revision: 20240610 |
| رمز التحديث: | 20240610 |
| DOI: | 10.1021/acs.biomac.4c00091 |
| PMID: | 38741285 |
| قاعدة البيانات: | MEDLINE |
Find this issue from the American Chemical Society | تدمد: | 1526-4602 |
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| DOI: | 10.1021/acs.biomac.4c00091 |