تقرير
Imatinib-induced dermatomyositis sine dermatitis - a rare case report.
العنوان: | Imatinib-induced dermatomyositis sine dermatitis - a rare case report. |
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المؤلفون: | Silva A; Rheumatology Department, EULAR Centre of Excellence, Unidade Local de Saúde Santa Maria, Lisbon Academic Medical Center and European Reference Network on Rare Connective Tissue and Musculoskeletal Diseases Network (ERN-ReCONNET), Lisbon, Portugal.; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal., Romão VC; Rheumatology Department, EULAR Centre of Excellence, Unidade Local de Saúde Santa Maria, Lisbon Academic Medical Center and European Reference Network on Rare Connective Tissue and Musculoskeletal Diseases Network (ERN-ReCONNET), Lisbon, Portugal.; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal., Campanilho-Marques R; Rheumatology Department, EULAR Centre of Excellence, Unidade Local de Saúde Santa Maria, Lisbon Academic Medical Center and European Reference Network on Rare Connective Tissue and Musculoskeletal Diseases Network (ERN-ReCONNET), Lisbon, Portugal.; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal.; Unidade de Reumatologia Pediátrica, Unidade Local de Saúde Santa Maria, Lisbon, Portugal. |
المصدر: | Frontiers in immunology [Front Immunol] 2024 Apr 29; Vol. 15, pp. 1398453. Date of Electronic Publication: 2024 Apr 29 (Print Publication: 2024). |
نوع المنشور: | Case Reports |
اللغة: | English |
بيانات الدورية: | Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE |
أسماء مطبوعة: | Original Publication: [Lausanne : Frontiers Research Foundation] |
مواضيع طبية MeSH: | Dermatomyositis*/chemically induced , Dermatomyositis*/diagnosis , Dermatomyositis*/immunology , Imatinib Mesylate*/adverse effects , Imatinib Mesylate*/therapeutic use, Humans ; Female ; Aged ; Antineoplastic Agents/adverse effects ; Antineoplastic Agents/therapeutic use ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/drug therapy ; Dermatitis/etiology ; Dermatitis/diagnosis ; Dermatitis/drug therapy |
مستخلص: | Idiopathic Inflammatory Myopathies are rare conditions with several heterogeneous disease subtypes. They can range from limited muscle or skin involvement to severe, systemic, life-threatening disease. Although the etiology is unknown, some evidence suggests a role for external agents, particularly drugs. Herein, we present a case of a 71-year-old woman with chronic myeloid leukemia who developed imatinib-induced dermatomyositis sine dermatitis . The presentation was predominantly muscular, characterized by proximal muscle weakness and myalgia of the lower limbs, with positive anti-Mi2a antibodies. Spontaneous recovery was observed after drug discontinuation, without the need for immunosuppressive therapy. This is the first confirmed description of an imatinib-induced dermatomyositis sine dermatitis. It reflects the importance of a high awareness from rheumatologists and hematologists to accurately anticipate and identify similar situations. Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2024 Silva, Romão and Campanilho-Marques.) |
References: | J Am Acad Dermatol. 2020 Feb;82(2):267-281. (PMID: 31279808) Presse Med. 1987 Feb 7;16(4):155-8. (PMID: 2950445) Rev Med Suisse. 2015 Jan 14;11(456-457):25-9. (PMID: 25799647) Front Immunol. 2022 Mar 17;13:857030. (PMID: 35371082) Leuk Res. 2010 Jun;34(6):827-9. (PMID: 19963273) N Engl J Med. 2008 Jun 19;358(25):2746-7. (PMID: 18565874) J Oncol Pharm Pract. 2023 Apr 10;:10781552231168563. (PMID: 37038366) J Clin Neuromuscul Dis. 2004 Mar;5(3):119-21. (PMID: 19078731) Int J Dermatol. 2006 Oct;45(10):1249-51. (PMID: 17040457) J Intern Med. 2016 Jul;280(1):8-23. (PMID: 26602539) Clin Exp Immunol. 2014 Mar;175(3):349-58. (PMID: 23981102) Clin Exp Rheumatol. 2023 Mar;41(2):199-213. (PMID: 36826800) Am J Case Rep. 2020 Jan 20;21:e917801. (PMID: 31958335) Intern Med J. 2021 Jun;51(6):845-852. (PMID: 34155760) Asia Pac J Clin Oncol. 2021 Jun;17(3):178-185. (PMID: 32717098) Leukemia. 2019 Aug;33(8):2116-2120. (PMID: 30872782) |
فهرسة مساهمة: | Keywords: autoantibodies; dermatomyositis sine dermatitis; imatinib mesylate; inflammatory myopathies; proximal muscle weakness |
تواريخ الأحداث: | Date Created: 20240515 Date Completed: 20240515 Latest Revision: 20240516 |
رمز التحديث: | 20240516 |
مُعرف محوري في PubMed: | PMC11092370 |
DOI: | 10.3389/fimmu.2024.1398453 |
PMID: | 38745660 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1664-3224 |
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DOI: | 10.3389/fimmu.2024.1398453 |