دورية أكاديمية
Alterations in the tear film and ocular surface in pediatric migraine patients.
| العنوان: | Alterations in the tear film and ocular surface in pediatric migraine patients. |
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| المؤلفون: | Asik A; Department of Pediatrics, Adıyaman University Education and Research Hospital, Adıyaman, Turkey., Aksoy Aydemir G; Department of Ophthalmology, Adıyaman University Education and Research Hospital, Adıyaman, Turkey., Aydemir E; Department of Ophthalmology, Adıyaman University Education and Research Hospital, Adıyaman, Turkey., Bilen A; Department of Ophthalmology, Adıyaman University Education and Research Hospital, Adıyaman, Turkey., Ipek R; Department of Pediatrics Neurology, Adıyaman University Education and Research Hospital, Adıyaman, Turkey., Ballı H; Department of Pediatrics, Adıyaman University Education and Research Hospital, Adıyaman, Turkey., Bayat AH; Department of Ophthalmology, Istanbul Medipol University, Istanbul, Turkey., Türk BA; Department of Pathology, Adıyaman University Education and Research Hospital, Adıyaman, Turkey. |
| المصدر: | Indian journal of ophthalmology [Indian J Ophthalmol] 2024 May 20. Date of Electronic Publication: 2024 May 20. |
| Publication Model: | Ahead of Print |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Medknow Publications Country of Publication: India NLM ID: 0405376 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1998-3689 (Electronic) Linking ISSN: 03014738 NLM ISO Abbreviation: Indian J Ophthalmol Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Mumbai : Medknow Publications Original Publication: Bombay : All-India Ophthalmological Society |
| مستخلص: | Purpose: To evaluate the ocular surface (OS) parameters in the pediatric migraine patients (PMPs). Methods: This prospective case-control study consisted of 51 PMPs (PMP group) and 55 healthy pediatric patients (HPP group). In all participants, tear function was evaluated subjectively using the Ocular Surface Disease Index (OSDI) questionnaire, objectively using Schirmer tear test (STT) and tear film disintegration time (TBUT), and with clinical and laboratory examinations (conjunctival impression cytology). The PMP group was subdivided into two groups according to their aura. Results: The mean age and gender distribution of the study groups were almost the same ( P > 0.05 for both of them). In the PMP group, both the STT value and the TBUT value were significantly lower than those determined in the HPP group ( P = 0.021 and P = 0.018, respectively). In the PMP group, the OSDI scores were higher than those in the HPP group ( P = 0.032). In the PMP group, the goblet cell density values were lower than those in the HPP group ( P = 0.01). With regard to the aura, the TBUT and STT values were nonsignificantly lower in the PMP aura-positive group than in the PMP aura-negative group ( P > 0.05 for both of them). The OSDI assessment was similar in both the groups. With regard to the goblet cell count, it was observed to be less in the PMP aura-positive group than in the PMP aura-negative group ( P = 0.01). Conclusion: Influence of OS in children with migraine was also demonstrated using the samples taken from the conjunctiva. These changes were also demonstrated by objective tests such as STT and TBUT. Both clinical objective evaluations and pathologic changes were more prominent in the migraine with aura group. (Copyright © 2024 Copyright: © 2024 Indian Journal of Ophthalmology.) |
| تواريخ الأحداث: | Date Created: 20240520 Latest Revision: 20240521 |
| رمز التحديث: | 20240521 |
| DOI: | 10.4103/IJO.IJO_2594_23 |
| PMID: | 38767563 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 1998-3689 |
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| DOI: | 10.4103/IJO.IJO_2594_23 |