دورية أكاديمية
أعرض في EDS

Comprehensive outcomes after Roux-en-Y gastric bypass with a near-complete 15-year follow-up.

التفاصيل البيبلوغرافية
العنوان: Comprehensive outcomes after Roux-en-Y gastric bypass with a near-complete 15-year follow-up.
المؤلفون: Jawhar N; Department of Surgery, Mayo Clinic, Rochester, MN., Abi Mosleh K; Department of Surgery, Mayo Clinic, Rochester, MN., Bartosiak KZ; Department of Surgery, Mayo Clinic, Rochester, MN., Hage K; Department of Surgery, Mayo Clinic, Rochester, MN., Kennel KA; Division of Endocrinology, Department of Internal Medicine, Mayo Clinic, Rochester, MN., Mundi MS; Division of Endocrinology, Department of Internal Medicine, Mayo Clinic, Rochester, MN., Kendrick ML; Department of Surgery, Mayo Clinic, Rochester, MN., Ghanem OM; Department of Surgery, Mayo Clinic, Rochester, MN. Electronic address: ghanem.omar@mayo.edu.
المصدر: Surgery [Surgery] 2024 Sep; Vol. 176 (3), pp. 586-594. Date of Electronic Publication: 2024 May 19.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Mosby Country of Publication: United States NLM ID: 0417347 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-7361 (Electronic) Linking ISSN: 00396060 NLM ISO Abbreviation: Surgery Subsets: MEDLINE
أسماء مطبوعة: Publication: St. Louis, MO : Mosby
Original Publication: St. Louis.
مواضيع طبية MeSH: Gastric Bypass*/methods , Gastric Bypass*/adverse effects , Weight Loss* , Laparoscopy*/methods , Laparoscopy*/adverse effects , Obesity, Morbid*/surgery , Obesity, Morbid*/complications, Humans ; Female ; Male ; Middle Aged ; Retrospective Studies ; Adult ; Follow-Up Studies ; Treatment Outcome ; Diabetes Mellitus, Type 2/complications ; Diabetes Mellitus, Type 2/surgery ; Recurrence ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Body Mass Index
مستخلص: Background: Laparoscopic Roux-en-Y gastric bypass has a well-established safety and efficacy profile in the short and mid-term. Long-term outcomes remain limited in the literature, especially for follow-up periods of >10 years. The purpose of the study is to evaluate the long-term durability and safety of laparoscopic Roux-en-Y gastric bypass over a near-complete 15-year follow-up.
Methods: This is a single-center retrospective cohort study of patients who underwent primary laparoscopic Roux-en-Y gastric bypass between 2008 and 2009 with ≥14-year follow-up. Data collected and analyzed were weight loss, obesity-related medical condition resolution and recurrence, weight recurrence, complication rate, and mortality rate.
Results: A total of 264 patients were included. Patients were predominantly female (81.8%), and the mean age and preoperative body mass index were 48.5 ± 12.2 years and 44.9 ± 7.3 kg/m 2 , respectively. The maximum mean percentage total weight loss achieved at 1 year was 31.5% ± 5.7% and was consistently >20% throughout follow-up. Sustained resolution of obesity-related medical conditions was achieved with a remission rate of 60.8% for type 2 diabetes mellitus, 46.7% for denoted dyslipidemia, and 40% for hypertension. Obesity-related medical condition recurrence was observed with a recurrence rate of 24.1% for type 2 diabetes mellitus, 17.9% for hypertension, and 14.8% for denoted dyslipidemia. Significant factors associated with weight loss were maximum percentage total weight loss and preoperative type 2 diabetes mellitus. Over 15 years, the weight recurrence rate was 51.1%, with predictors of higher preoperative body mass index and preoperative type 2 diabetes mellitus.
Conclusion: Laparoscopic Roux-en-Y gastric bypass provides sustainable weight loss over a 15-year period, with consistent long-term weight-loss outcomes and resolution of obesity-related medical conditions sustained for ≥10 years after surgery.
(Copyright © 2024 Elsevier Inc. All rights reserved.)
تواريخ الأحداث: Date Created: 20240520 Date Completed: 20240816 Latest Revision: 20240816
رمز التحديث: 20240818
DOI: 10.1016/j.surg.2024.02.035
PMID: 38769035
قاعدة البيانات: MEDLINE
الوصف
تدمد:1532-7361
DOI:10.1016/j.surg.2024.02.035