Long- vs short-segment Barrett's esophagus-derived adenocarcinoma: clinical features and outcomes of endoscopic submucosal dissection.

التفاصيل البيبلوغرافية
العنوان:	Long- vs short-segment Barrett's esophagus-derived adenocarcinoma: clinical features and outcomes of endoscopic submucosal dissection.
المؤلفون:	Ikenoyama Y; Department of Gastroenterology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan. 0801yohei@med.mie-u.ac.jp.; Department of Gastroenterology and Hepatology, Mie University Hospital, 2-174 Edobashi, Tsu, Mie, 514-8507, Japan. 0801yohei@med.mie-u.ac.jp., Namikawa K; Department of Gastroenterology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan., Takamatsu M; Department of Pathology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan.; Division of Pathology, Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan., Kumazawa Y; Department of Gastroenterology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan., Tokai Y; Department of Gastroenterology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan., Yoshimizu S; Department of Gastroenterology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan., Horiuchi Y; Department of Gastroenterology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan., Ishiyama A; Department of Gastroenterology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan., Yoshio T; Department of Gastroenterology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan., Hirasawa T; Department of Gastroenterology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan., Fujisaki J; Department of Gastroenterology, Cancer Institute Hospital, Japanese Foundation for Cancer Research, Tokyo, Japan.
المصدر:	Surgical endoscopy [Surg Endosc] 2024 Jul; Vol. 38 (7), pp. 3636-3644. Date of Electronic Publication: 2024 May 20.
نوع المنشور:	Journal Article; Comparative Study
اللغة:	English
بيانات الدورية:	Publisher: Springer Country of Publication: Germany NLM ID: 8806653 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-2218 (Electronic) Linking ISSN: 09302794 NLM ISO Abbreviation: Surg Endosc Subsets: MEDLINE
أسماء مطبوعة:	Publication: 1992- : New York : Springer Original Publication: [Berlin] : Springer International, c1987-
مواضيع طبية MeSH:	Barrett Esophagus/surgery , Barrett Esophagus/pathology , Endoscopic Mucosal Resection/methods , Adenocarcinoma/surgery , Adenocarcinoma/pathology , Esophageal Neoplasms/pathology , Esophageal Neoplasms*/surgery, Humans ; Male ; Female ; Retrospective Studies ; Aged ; Middle Aged ; Treatment Outcome ; Esophagoscopy/methods
مستخلص:	Background: The incidence of Barrett's esophageal adenocarcinoma (BEA) is increasing, and endoscopic submucosal dissection (ESD) has been frequently performed for its treatment. However, the differences between the characteristics and ESD outcomes between short- and long-segment BEA (SSBEA and LSBEA, respectively) are unclear. We compared the clinicopathological characteristics and short- and long-term outcomes of ESD between both groups. Methods: We retrospectively reviewed 155 superficial BEAs (106 SSBEAs and 49 LSBEAs) treated with ESD in 139 patients and examined their clinicopathological features and ESD outcomes. SSBEA and LSBEA were classified based on whether the maximum length of the background mucosa of BEA was < 3 cm or ≥ 3 cm, respectively. Results: Compared with SSBEA, LSBEA showed significantly higher proportions of cases with the macroscopically flat type (36.7% vs. 5.7%, p < 0.001), left wall location (38.8% vs. 11.3%, p < 0.001), over half of the tumor circumference (20.4% vs. 1.9%, p < 0.001), and synchronous lesions (17.6% vs. 0%, p < 0.001). Compared with SSBEA, regarding ESD outcomes, LSBEA showed significantly longer resection duration (91.0 min vs. 60.5 min, p < 0.001); a lower proportion of submucosal invasion (14.3% vs. 29.2%, p = 0.047), horizontal margin negativity (79.6% vs. 94.3%, p = 0.0089), and R0 resection (69.4% vs. 86.8%, p = 0.024); and a higher proportion of post-procedural stenosis cases (10.9% vs. 1.9%, p = 0.027). The 5-year cumulative incidence of metachronous cancer in patients without additional treatment was significantly higher for LSBEA than for SSBEA (25.0% vs. 0%, p < 0.001). Conclusions: The clinicopathological features of LSBEA and SSBEA and their treatment outcomes differed in many aspects. As LSBEAs are difficult to diagnose and treat and show a high risk of metachronous cancer development, careful ESD and follow-up or eradication of the remaining BE may be required. (© 2024. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.)
References:	Pohl H, Sirovich B, Welch HG (2010) Esophageal adenocarcinoma incidence: are we reaching the peak? Cancer Epidemiol Biomarkers Prev 19:1468–1470. (PMID: 10.1158/1055-9965.EPI-10-001220501776) Hongo M, Nagasaki Y, Shoji T (2009) Epidemiology of esophageal cancer: orient to occident. Effects of chronology, geography and ethnicity. J Gastroenterol Hepatol 24:729–735. (PMID: 10.1111/j.1440-1746.2009.05824.x19646015) Sharma P, Dent J, Armstrong D, Bergman JJ, Gossner L, Hoshihara Y, Jankowski JA, Junghard O, Lundell L, Tytgat GN, Vieth M (2006) The development and validation of an endoscopic grading system for Barrett’s esophagus: the Prague C & M criteria. Gastroenterology 131:1392–1399. (PMID: 10.1053/j.gastro.2006.08.03217101315) Shihara R, Arima M, Iizuka T, Oyama T, Katada C, Kato M, Goda K, Goto O, Tanaka K, Yano T, Yoshinaga S, Muto M, Kawakubo H, Fujishiro M, Yoshida M, Fujimoto K, Tajiri H, Inoue H (2020) Endoscopic submucosal dissection/endoscopic mucosal resection guidelines for esophageal cancer. Dig Endosc 32:452–493. (PMID: 10.1111/den.13654) Pfaffenbach B, Hullerum J, Orth KH, Langer M, Stabenow-Lohbauer U, Lux G (2000) Bile and acid reflux in long and short segment Barrett’s esophagus, and in reflux disease. Z Gastroenterol 38:565–570. (PMID: 10.1055/s-2000-745010965553) Abe S, Ishihara R, Takahashi H, Ono H, Fujisaki J, Matsui A, Takahashi A, Goda K, Kawada K, Koike T, Takeuchi M, Tsuji Y, Hirasawa D, Oyama T (2019) Long-term outcomes of endoscopic resection and metachronous cancer after endoscopic resection for adenocarcinoma of the esophagogastric junction in Japan. Gastrointest Endosc 89:1120–1128. (PMID: 10.1016/j.gie.2018.12.01030576649) Kagemoto K, Oka S, Tanaka S, Miwata T, Urabe Y, Sanomura Y, Yoshida S, Hiyama T, Arihiro K, Chayama K (2014) Clinical outcomes of endoscopic submucosal dissection for superficial Barrett’s adenocarcinoma. Gastrointest Endosc 80:239–245. (PMID: 10.1016/j.gie.2014.01.02224565073) Shimizu T, Fujisaki J, Omae M, Yamasaki A, Horiuchi Y, Ishiyama A, Yoshio T, Hirasawa T, Yamamoto Y, Tsuchida T (2018) Treatment outcomes of endoscopic submucosal dissection for adenocarcinoma originating from long-segment Barrett’s esophagus versus short-segment Barrett’s esophagus. Digestion 97:316–323. (PMID: 10.1159/00048619729539629) Subramaniam S, Chedgy F, Longcroft-Wheaton G, Kandiah K, Maselli R, Seewald S, Repici A, Bhandari P (2017) Complex early Barrett’s neoplasia at 3 Western centers: European Barrett’s Endoscopic Submucosal Dissection Trial (E-BEST). Gastrointest Endosc 86:608–618. (PMID: 10.1016/j.gie.2017.01.02728159540) Probst A, Aust D, Märkl B, Anthuber M, Messmann H (2015) Early esophageal cancer in Europe: endoscopic treatment by endoscopic submucosal dissection. Endoscopy 47:113–121. (PMID: 25479563) Japan Esophageal Society (2017) Japanese classification of esophageal cancer: Part II and III. Esophagus 14:37–65. (PMID: 10.1007/s10388-016-0556-2) Japan Esophageal Society (2017) Japanese classification of esophageal cancer: Part I. Esophagus 14:1–36. (PMID: 10.1007/s10388-016-0551-7) Fitzgerald RC, di Pietro M, Ragunath K, Ang Y, Kang JY, Watson P, Trudgill N, Patel P, Kaye PV, Sanders S, O’Donovan M, Bird-Lieberman E, Bhandari P, Jankowski JA, Attwood S, Parsons SL, Loft D, Lagergren J, Moayyedi P, Lyratzopoulos G, de Caestecker J (2014) British Society of Gastroenterology guidelines on the diagnosis and management of Barrett’s oesophagus. Gut 63:7–42. (PMID: 10.1136/gutjnl-2013-30537224165758) Fock KM, Talley N, Goh KL, Sugano K, Katelaris P, Holtmann G, Pandolfino JE, Sharma P, Ang TL, Hongo M, Wu J, Chen M, Choi MG, Law NM, Sheu BS, Zhang J, Ho KY, Sollano J, Rani AA, Kositchaiwat C, Bhatia S (2016) Asia-Pacific consensus on the management of gastro-oesophageal reflux disease: an update focusing on refractory reflux disease and Barrett’s oesophagus. Gut 65:1402–1415. (PMID: 10.1136/gutjnl-2016-31171527261337) Kimura K, Takemoto T (1969) An endoscopic recognition of the atrophic border and its significance in chronic gastritis. Endoscopy 1:87–97. (PMID: 10.1055/s-0028-1098086) Armstrong D, Bennett JR, Blum AL, Dent J, De Dombal FT, Galmiche JP, Lundell L, Margulies M, Richter JE, Spechler SJ, Tytgat GN, Wallin L (1996) The endoscopic assessment of esophagitis: a progress report on observer agreement. Gastroenterology 111:85–92. (PMID: 10.1053/gast.1996.v111.pm86982308698230) No Authors (2003) The Paris endoscopic classification of superficial neoplastic lesions: esophagus, stomach, and colon: November 30 to December 1, 2002. Gastrointest Endosc 58:S3–S43. (PMID: 10.1016/S0016-5107(03)02159-X) Ishihara R, Oyama T, Abe S, Takahashi H, Ono H, Fujisaki J, Kaise M, Goda K, Kawada K, Koike T, Takeuchi M, Matsuda R, Hirasawa D, Yamada M, Kodaira J, Tanaka M, Omae M, Matsui A, Kanesaka T, Takahashi A, Hirooka S, Saito M, Tsuji Y, Maeda Y, Yamashita H, Oda I, Tomita Y, Matsunaga T, Terai S, Ozawa S, Kawano T, Seto Y (2017) Risk of metastasis in adenocarcinoma of the esophagus: a multicenter retrospective study in a Japanese population. J Gastroenterol 52:800–808. (PMID: 10.1007/s00535-016-1275-027757547) Moertel CG, Dockerty MB, Baggenstoss AH (1961) Multiple primary malignant neoplasms. I. Introduction and presentation of data. Cancer 14:221–230. (PMID: 10.1002/1097-0142(196103/04)14:2<221::AID-CNCR2820140202>3.0.CO;2-613771652) Pech O, Gossner L, Manner H, May A, Rabenstein T, Behrens A, Berres M, Huijsmans J, Vieth M, Stolte M, Ell C (2007) Prospective evaluation of the macroscopic types and location of early Barrett’s neoplasia in 380 lesions. Endoscopy 39:588–593. (PMID: 10.1055/s-2007-96636317611912) Enestvedt BK, Lugo R, Guarner-Argente C, Shah P, Falk GW, Furth E, Ginsberg GG (2013) Location, location, location: does early cancer in Barrett’s esophagus have a preference? Gastrointest Endosc 78:462–467. (PMID: 10.1016/j.gie.2013.03.16723622975) Yamasaki A, Shimizu T, Kawachi H, Yamamoto N, Yoshimizu S, Horiuchi Y, Ishiyama A, Yoshio T, Hirasawa T, Tsuchida T, Sasaki Y, Fujisaki J (2020) Endoscopic features of esophageal adenocarcinoma derived from short-segment versus long-segment Barrett’s esophagus. J Gastroenterol Hepatol 35:211–217. (PMID: 10.1111/jgh.1482731396997) Mitsui T, Kadota T, Wakabayashi M, Nakajo K, Shinmura K, Sunakawa H, Sato D, Minamide T, Takashima K, Murano T, Yoda Y, Ikematsu H, Yano T (2022) Factors of technical difficulty in conventional and traction-assisted esophageal endoscopic submucosal dissection. Esophagus 19:452–459. (PMID: 10.1007/s10388-022-00913-w35235089) Yang D, Zou F, Xiong S, Forde JJ, Wang Y, Draganov PV (2018) Endoscopic submucosal dissection for early Barrett’s neoplasia: a meta-analysis. Gastrointest Endosc 87:1383–1393. (PMID: 10.1016/j.gie.2017.09.03828993137) Ikenoyama Y, Tanaka K, Umeda Y, Hamada Y, Yukimoto H, Yamada R, Tsuboi J, Nakamura M, Katsurahara M, Horiki N, Nakagawa H (2022) Effect of adding acetic acid when performing magnifying endoscopy with narrow band imaging for diagnosis of Barrett’s esophageal adenocarcinoma. Endosc Int Open 10:E1528–E1536. (PMID: 10.1055/a-1948-2910365316739754883) Phillips R, Januszewicz W, Pilonis ND, O’Donovan M, Sawas T, Katzka DA, Fitzgerald RC, di Pietro M (2021) The risk of neoplasia in patients with Barrett’s esophagus indefinite for dysplasia: a multicenter cohort study. Gastrointest Endosc 94:263-270.e2. (PMID: 10.1016/j.gie.2021.01.042335482817611297) Shaheen NJ, Falk GW, Iyer PG, Gerson LB, American College of Gastroenterology (2016) ACG clinical guideline: diagnosis and management of Barrett's esophagus. Am J Gastroenterol 111:30–50; quiz 51. Weusten B, Bisschops R, Coron E, Dinis-Ribeiro M, Dumonceau JM, Esteban JM, Hassan C, Pech O, Repici A, Bergman J, di Pietro M (2017) Endoscopic management of Barrett’s esophagus: European Society of Gastrointestinal Endoscopy (ESGE) Position Statement. Endoscopy 49:191–198. (PMID: 10.1055/s-0042-12214028122386) Orman ES, Li N, Shaheen NJ (2013) Efficacy and durability of radiofrequency ablation for Barrett’s esophagus: systematic review and meta-analysis. Clin Gastroenterol Hepatol 11:1245–1255. (PMID: 10.1016/j.cgh.2013.03.03923644385) Abe K, Goda K, Kanamori A, Suzuki T, Yamamiya A, Takimoto Y, Arisaka T, Hoshi K, Sugaya T, Majima Y, Tominaga K, Iijima M, Hirooka S, Yamagishi H, Irisawa A (2021) Whole circumferential endoscopic submucosal dissection of superficial adenocarcinoma in long-segment Barrett’s esophagus: a case report. World J Gastrointest Surg 13:1285–1292. (PMID: 10.4240/wjgs.v13.i10.1285347543968554727) Tanaka I, Hirasawa D, Saito H, Akahira J, Fujishima F, Matsuda T (2022) Stepwise endoscopic submucosal dissection for circumferential Barrett’s esophageal dysplasia and carcinoma: a case series. Endosc Int Open 10:E215–E221. (PMID: 10.1055/a-1672-4122351783408847047)
فهرسة مساهمة:	Keywords: Barrett’s esophageal adenocarcinoma; Endoscopic submucosal dissection; Long-segment Barrett’s esophagus; Metachronous cancer; Short-segment Barrett’s esophagus
SCR Disease Name:	Adenocarcinoma Of Esophagus
تواريخ الأحداث:	Date Created: 20240520 Date Completed: 20240702 Latest Revision: 20240702
رمز التحديث:	20240702
DOI:	10.1007/s00464-024-10888-7
PMID:	38769185
قاعدة البيانات:	MEDLINE

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تدمد:	1432-2218
DOI:	10.1007/s00464-024-10888-7