دورية أكاديمية
Identification and Functional Characterization of a Surfactant-like Protein Region in Flagellin FliC for Stabilizing Selenium Nanoparticles and Enhancing Bioavailability.
| العنوان: | Identification and Functional Characterization of a Surfactant-like Protein Region in Flagellin FliC for Stabilizing Selenium Nanoparticles and Enhancing Bioavailability. |
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| المؤلفون: | Li K; College of Resources and Environmental Sciences, China Agricultural University, Beijing 100193, China.; Beijing Key Laboratory of Biodiversity and Organic Farming, China Agricultural University, Beijing 100193, China., Zhang J; College of Resources and Environmental Sciences, China Agricultural University, Beijing 100193, China.; Beijing Key Laboratory of Biodiversity and Organic Farming, China Agricultural University, Beijing 100193, China., Zhang S; College of Resources and Environmental Sciences, China Agricultural University, Beijing 100193, China.; Beijing Key Laboratory of Biodiversity and Organic Farming, China Agricultural University, Beijing 100193, China., Xu Q; College of Resources and Environmental Sciences, China Agricultural University, Beijing 100193, China.; Beijing Key Laboratory of Biodiversity and Organic Farming, China Agricultural University, Beijing 100193, China., Guo Y; College of Resources and Environmental Sciences, China Agricultural University, Beijing 100193, China.; Beijing Key Laboratory of Biodiversity and Organic Farming, China Agricultural University, Beijing 100193, China. |
| المصدر: | Journal of agricultural and food chemistry [J Agric Food Chem] 2024 Jun 05; Vol. 72 (22), pp. 12673-12684. Date of Electronic Publication: 2024 May 21. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 0374755 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5118 (Electronic) Linking ISSN: 00218561 NLM ISO Abbreviation: J Agric Food Chem Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Washington, American Chemical Society. |
| مواضيع طبية MeSH: | Selenium*/chemistry , Selenium*/metabolism , Flagellin*/chemistry , Flagellin*/metabolism , Biological Availability* , Surface-Active Agents*/chemistry , Surface-Active Agents*/metabolism , Nanoparticles*/chemistry, Triticum/chemistry ; Triticum/metabolism ; Bacterial Proteins/chemistry ; Bacterial Proteins/metabolism ; Bacterial Proteins/genetics |
| مستخلص: | Biogenic selenium nanoparticles (SeNPs) are the most favorable Se form for nutritional supplementation due to their high stability, low toxicity, and high activity. However, the interaction between the surface-binding proteins and their stable biogenic SeNPs, as well as their impact on the stability and bioavailability of SeNPs, remains to be understood. In vitro stabilization experiments revealed an amino acid segment (F(235-386)) in Rahnella aquatilis ' flagellin FliC, with surfactant-like properties, stabilizing SeNPs under harsh conditions. FliC and F(235-386) were employed as stabilizers to synthesize SeNPs (FliC@SeNPs and F(235-386)@SeNPs), and surface chemistry analysis revealed coordination reactions between the proteins and Se atoms on the surface of SeNPs. Both FliC and F(235-386) enhanced SeNPs uptake in wheat seedlings but reduced it in bacteria and yeast. This study highlights FliC's core function in stabilizing SeNPs and enhancing their bioavailability, paving the way for agricultural and nutritional applications. |
| فهرسة مساهمة: | Keywords: bioavailibility; flagellin FliC; selenium nanoparticles; stabilization; surfactant-like protein |
| المشرفين على المادة: | H6241UJ22B (Selenium) 12777-81-0 (Flagellin) 0 (Surface-Active Agents) 0 (Bacterial Proteins) |
| تواريخ الأحداث: | Date Created: 20240521 Date Completed: 20240605 Latest Revision: 20240709 |
| رمز التحديث: | 20240709 |
| DOI: | 10.1021/acs.jafc.4c02402 |
| PMID: | 38772747 |
| قاعدة البيانات: | MEDLINE |
Find this issue from the American Chemical Society | تدمد: | 1520-5118 |
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| DOI: | 10.1021/acs.jafc.4c02402 |