دورية أكاديمية
Infection complicating locked intramedullary nailing of open lower-extremity fractures: incidence, associated risk factors, and lessons for improving outcome in a low-resource setting.
| العنوان: | Infection complicating locked intramedullary nailing of open lower-extremity fractures: incidence, associated risk factors, and lessons for improving outcome in a low-resource setting. |
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| المؤلفون: | Adesina SA; Department of Family Medicine, Bowen University, Iwo, 232102, Nigeria., Amole IO; Department of Family Medicine, Bowen University, Iwo, 232102, Nigeria., Akinwumi AI; Department of Family Medicine, Afe Babalola University, Ado-Ekiti, 360101, Nigeria., Adegoke AO; Department of Family Medicine, Bowen University, Iwo, 232102, Nigeria., Owolabi JI; Department of Surgery, Bowen University, Iwo, 232102, Nigeria., Adefokun IG; Department of Surgery, Bowen University Teaching Hospital, Ogbomoso, 210001, Nigeria., Durodola AO; Department of Family Medicine, Bowen University, Iwo, 232102, Nigeria., Awotunde OT; Department of Family Medicine, Bowen University, Iwo, 232102, Nigeria., Eyesan SU; Department of Surgery, Bowen University, Iwo, 232102, Nigeria. |
| المصدر: | Journal of bone and joint infection [J Bone Jt Infect] 2023 Feb 14; Vol. 8 (1), pp. 71-79. Date of Electronic Publication: 2023 Feb 14 (Print Publication: 2023). |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Copernicus Publications Country of Publication: Germany NLM ID: 101701849 Publication Model: eCollection Cited Medium: Print ISSN: 2206-3552 (Print) Linking ISSN: 22063552 NLM ISO Abbreviation: J Bone Jt Infect Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Publication: 2020- : [Göttingen] : Copernicus Publications Original Publication: Sydney : Ivyspring International Publisher, [2016]- |
| مستخلص: | Introduction : Infection is the chief complication that makes open fractures difficult to treat. Most low- and middle-income countries (LMICs) are missing out on modern management techniques developed to achieve better outcomes in high-income countries (HICs). One of these is the use of locked intramedullary (IM) nails. This study aimed to determine the factors associated with infection of open fractures treated with the surgical implant generation network (SIGN) nail at a Nigerian tertiary hospital. Methods : Data were collected prospectively on 101 open fractures of the femur and tibia over an 8-year period. Active surveillance for infection was done on each patient. Infection was diagnosed as the presence of wound breakdown or purulent discharge from (or near) the wound or surgical incision. Potential risk factors were tested for association with infection. Results : There were 101 fractures in 94 patients with a mean age of 37.76 years. The following treatment-related factors demonstrated significant associations with infection - timings of antibiotic administration ( p < 0.001 ) and definitive fracture fixation ( p = 0.002 ); definitive wound closure ( p < 0.001 ), fracture-reduction methods ( p = 0.005 ), and surgery duration ( p = 0.007 ). Conclusions : Although this study has limitations precluding the drawing up of final conclusions, the findings suggest that the risk factors for infection of nailed open fractures in LMICs are similar to those in HICs. Consequently, outcomes can potentially improve if LMICs adopt the management principles used in HICs in scientifically sound ways that are affordable and socially acceptable to their people. Further studies are suggested to establish our findings. Competing Interests: The contact author has declared that none of the authors has any competing interests. (Copyright: © 2023 Stephen A. Adesina et al.) |
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| تواريخ الأحداث: | Date Created: 20240522 Latest Revision: 20240523 |
| رمز التحديث: | 20240523 |
| مُعرف محوري في PubMed: | PMC11106765 |
| DOI: | 10.5194/jbji-8-71-2023 |
| PMID: | 38774303 |
| قاعدة البيانات: | MEDLINE |
Full Text Finder | تدمد: | 2206-3552 |
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| DOI: | 10.5194/jbji-8-71-2023 |