دورية أكاديمية
Ethnic minorities treated with new-generation drug-eluting coronary stents in two European randomised clinical trials.
| العنوان: | Ethnic minorities treated with new-generation drug-eluting coronary stents in two European randomised clinical trials. |
|---|---|
| المؤلفون: | Ploumen EH; Department of Cardiology, Thoraxcentrum Twente, Medisch Spectrum Twente, Enschede, The Netherlands.; Health Technology and Services Research, Faculty of Behavioural, Management and Social Sciences, Technical Medical Centre, University of Twente, Enschede, The Netherlands., Semedo E; Department of Cardiology, Thoraxcentrum Twente, Medisch Spectrum Twente, Enschede, The Netherlands.; Health Technology and Services Research, Faculty of Behavioural, Management and Social Sciences, Technical Medical Centre, University of Twente, Enschede, The Netherlands., Doggen CJM; Health Technology and Services Research, Faculty of Behavioural, Management and Social Sciences, Technical Medical Centre, University of Twente, Enschede, The Netherlands., Schotborgh CE; Department of Cardiology, Haga Hospital, The Hague, The Netherlands., Anthonio RL; Department of Cardiology, Treant Zorggroep, Scheper Hospital, Emmen, The Netherlands., Danse PW; Department of Cardiology, Rijnstate Hospital, Arnhem, The Netherlands., Benit E; Department of Cardiology, Jessa Hospital, Hasselt, Belgium., Aminian A; Department of Cardiology, Centre Hospitalier Universitaire de Charleroi, Charleroi, Belgium., Stoel MG; Department of Cardiology, Thoraxcentrum Twente, Medisch Spectrum Twente, Enschede, The Netherlands., Hartmann M; Department of Cardiology, Thoraxcentrum Twente, Medisch Spectrum Twente, Enschede, The Netherlands., van Houwelingen KG; Department of Cardiology, Thoraxcentrum Twente, Medisch Spectrum Twente, Enschede, The Netherlands., Scholte M; Department of Cardiology, Albert Schweitzer Hospital, Dordrecht, The Netherlands., Roguin A; Department of Cardiology, Hillel Yaffe Medical Centre, Hadera and B. Rappaport-Faculty of Medicine, Israel, Institute of Technology, Haifa, Israel., Linssen GCM; Department of Cardiology, Hospital Group Twente, Almelo, The Netherlands., Zocca P; Department of Cardiology, Thoraxcentrum Twente, Medisch Spectrum Twente, Enschede, The Netherlands., von Birgelen C; Department of Cardiology, Thoraxcentrum Twente, Medisch Spectrum Twente, Enschede, The Netherlands. c.vonbirgelen@mst.nl.; Health Technology and Services Research, Faculty of Behavioural, Management and Social Sciences, Technical Medical Centre, University of Twente, Enschede, The Netherlands. c.vonbirgelen@mst.nl. |
| المصدر: | Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation [Neth Heart J] 2024 Jun; Vol. 32 (6), pp. 254-261. Date of Electronic Publication: 2024 May 22. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Bohn Stafleu van Loghum Country of Publication: Netherlands NLM ID: 101095458 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1568-5888 (Print) Linking ISSN: 15685888 NLM ISO Abbreviation: Neth Heart J Subsets: PubMed not MEDLINE |
| أسماء مطبوعة: | Publication: Houten : Bohn Stafleu van Loghum Original Publication: Leusden, The Netherlands : Mediselect bv, c2001- |
| مستخلص: | Background: Several ethnic minorities have an increased risk of cardiovascular events, but previous European trials that investigated clinical outcome after coronary stenting did not assess the patients' ethnic background. Aims: To compare ethnic minority and Western European trial participants in terms of both cardiovascular risk profile and 1‑year clinical outcome after percutaneous coronary intervention. Methods: In the BIO-RESORT and BIONYX randomised trials, which assessed new-generation drug-eluting stents, information on patients' self-reported ethnic background was prospectively collected. Pooled patient-level data of 5803 patients, enrolled in the Netherlands and Belgium, were analysed in this prespecified analysis. The main endpoint was target vessel failure after 1 year. Results: Patients were classified as belonging to an ethnic minority (n = 293, 5%) or of Western European origin (n = 5510, 95%). Follow-up data were available in 5772 of 5803 (99.5%) patients. Ethnic minority patients were younger, less often female, more often current smokers, more often medically treated for diabetes, and more often had a positive family history of coronary artery disease. The main endpoint target vessel failure did not differ between ethnic minority and Western European patients (3.5% vs 4.9%, hazard ratio 0.71, 95% confidence interval 0.38-1.33; p = 0.28). There was also no difference in mortality, myocardial infarction, and repeat revascularisation rates. Conclusions: Despite the unfavourable cardiovascular risk profile of ethnic minority patients, short-term clinical outcome after treatment with contemporary drug-eluting stents was highly similar to that in Western European patients. Further efforts should be made to ensure the enrolment of more ethnic minority patients in future coronary stent trials. (© 2024. The Author(s).) |
| References: | Can J Cardiol. 2016 Aug;32(8):987.e25-31. (PMID: 27177835) Int J Cardiol. 2020 May 15;307:17-23. (PMID: 32111358) Lancet. 2016 Nov 26;388(10060):2607-2617. (PMID: 27806902) Circulation. 2010 Sep 14;122(11):1085-90. (PMID: 20805432) Cardiovasc Revasc Med. 2014 Jun;15(4):214-8. (PMID: 24814420) J Interv Cardiol. 2013 Feb;26(1):49-57. (PMID: 22988961) Circulation. 2012 Jun 19;125(24):2963-4. (PMID: 22619285) JAMA Cardiol. 2017 Dec 01;2(12):1303-1313. (PMID: 29049508) Eur J Prev Cardiol. 2015 Oct;22(10):1281-9. (PMID: 25261269) Curr Opin Cardiol. 2020 Nov;35(6):705-711. (PMID: 32852343) Neth Heart J. 2020 Aug;28(Suppl 1):78-87. (PMID: 32780336) PLoS One. 2020 Jan 13;15(1):e0226606. (PMID: 31929543) J Am Heart Assoc. 2020 Mar 3;9(5):e013542. (PMID: 32114888) JACC Cardiovasc Interv. 2020 Jul 13;13(13):1586-1595. (PMID: 32646701) Circulation. 2013 Apr 2;127(13):1395-403. (PMID: 23547179) Heart Lung. 2014 Jul-Aug;43(4):270-7. (PMID: 24992880) Am J Cardiol. 2019 Oct 15;124(8):1179-1185. (PMID: 31439280) Am J Cardiol. 2009 Mar 1;103(5):653-8. (PMID: 19231328) EuroIntervention. 2010 Feb;5(7):871-4. (PMID: 20142206) J Am Heart Assoc. 2021 Jul 6;10(13):e020408. (PMID: 34182790) Lancet. 2018 Oct 6;392(10154):1235-1245. (PMID: 30253879) Circulation. 2007 May 1;115(17):2344-51. (PMID: 17470709) Vasc Health Risk Manag. 2012;8:505-15. (PMID: 22956878) Curr Cardiovasc Risk Rep. 2015 May;9(5):. (PMID: 25914758) Eur Heart J Qual Care Clin Outcomes. 2022 Aug 17;8(5):518-528. (PMID: 33892502) Dan Med J. 2015 Apr;62(4):B5068. (PMID: 25872539) JAMA Cardiol. 2020 Jun 1;5(6):714-722. (PMID: 32211813) Am J Cardiol. 2019 Mar 15;123(6):913-918. (PMID: 30595392) |
| فهرسة مساهمة: | Keywords: Coronary artery disease; Drug-eluting stent; Ethnic minority; Percutaneous coronary intervention; Race; Randomised clinical trial |
| تواريخ الأحداث: | Date Created: 20240522 Latest Revision: 20240603 |
| رمز التحديث: | 20240603 |
| مُعرف محوري في PubMed: | PMC11143136 |
| DOI: | 10.1007/s12471-024-01873-9 |
| PMID: | 38776038 |
| قاعدة البيانات: | MEDLINE |
Find this article in full text from Springer Verlag. 
Full Text Finder | تدمد: | 1568-5888 |
|---|---|
| DOI: | 10.1007/s12471-024-01873-9 |