دورية أكاديمية
Rapid determination of total flavonoid content, xanthine oxidase inhibitory activities, and antioxidant activity in Prunus mume by near-infrared spectroscopy.
العنوان: | Rapid determination of total flavonoid content, xanthine oxidase inhibitory activities, and antioxidant activity in Prunus mume by near-infrared spectroscopy. |
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المؤلفون: | Hao JW; College of Biotechnology and Pharmaceutical Engineering, West Anhui University, Lu'an City 237012, China; Anhui Province Key Laboratory for Quality Evaluation and Improvement of Traditional Chinese Medicine, Lu'an City 237012, China; Anhui Engineering Technology Center for Conservation and Utilization of Traditional Chinese Medicine Resource, Lu'an City 237012, China; Lu'an City Laboratory for Quality Evaluation and Improvement of Traditional Chinese Medicine, Lu'an City 237012, China., Chen ND; College of Biotechnology and Pharmaceutical Engineering, West Anhui University, Lu'an City 237012, China; Anhui Province Key Laboratory for Quality Evaluation and Improvement of Traditional Chinese Medicine, Lu'an City 237012, China; Anhui Engineering Technology Center for Conservation and Utilization of Traditional Chinese Medicine Resource, Lu'an City 237012, China; College of Pharmacy, Anhui University of Chinese Medicine, No 1. Qianjiang Road, Hefei City, Anhui Province 230012, PR China; Lu'an City Laboratory for Quality Evaluation and Improvement of Traditional Chinese Medicine, Lu'an City 237012, China. Electronic address: 2004cnd@163.com., Fan XX; College of Biotechnology and Pharmaceutical Engineering, West Anhui University, Lu'an City 237012, China; Anhui Province Key Laboratory for Quality Evaluation and Improvement of Traditional Chinese Medicine, Lu'an City 237012, China; College of Pharmacy, Anhui University of Chinese Medicine, No 1. Qianjiang Road, Hefei City, Anhui Province 230012, PR China., Wang WT; College of Biotechnology and Pharmaceutical Engineering, West Anhui University, Lu'an City 237012, China; Anhui Province Key Laboratory for Quality Evaluation and Improvement of Traditional Chinese Medicine, Lu'an City 237012, China; College of Pharmacy, Anhui University of Chinese Medicine, No 1. Qianjiang Road, Hefei City, Anhui Province 230012, PR China., Jiang HH; College of Biotechnology and Pharmaceutical Engineering, West Anhui University, Lu'an City 237012, China; Anhui Province Key Laboratory for Quality Evaluation and Improvement of Traditional Chinese Medicine, Lu'an City 237012, China; Anhui Engineering Technology Center for Conservation and Utilization of Traditional Chinese Medicine Resource, Lu'an City 237012, China; Lu'an City Laboratory for Quality Evaluation and Improvement of Traditional Chinese Medicine, Lu'an City 237012, China., Zhang ZY; College of Biotechnology and Pharmaceutical Engineering, West Anhui University, Lu'an City 237012, China; Anhui Province Key Laboratory for Quality Evaluation and Improvement of Traditional Chinese Medicine, Lu'an City 237012, China; Anhui Engineering Technology Center for Conservation and Utilization of Traditional Chinese Medicine Resource, Lu'an City 237012, China; Lu'an City Laboratory for Quality Evaluation and Improvement of Traditional Chinese Medicine, Lu'an City 237012, China., Gong RZ; College of Biotechnology and Pharmaceutical Engineering, West Anhui University, Lu'an City 237012, China; Anhui Province Key Laboratory for Quality Evaluation and Improvement of Traditional Chinese Medicine, Lu'an City 237012, China; Anhui Engineering Technology Center for Conservation and Utilization of Traditional Chinese Medicine Resource, Lu'an City 237012, China; Lu'an City Laboratory for Quality Evaluation and Improvement of Traditional Chinese Medicine, Lu'an City 237012, China., Ruan XL; College of Biotechnology and Pharmaceutical Engineering, West Anhui University, Lu'an City 237012, China; Anhui Province Key Laboratory for Quality Evaluation and Improvement of Traditional Chinese Medicine, Lu'an City 237012, China; Anhui Engineering Technology Center for Conservation and Utilization of Traditional Chinese Medicine Resource, Lu'an City 237012, China; Lu'an City Laboratory for Quality Evaluation and Improvement of Traditional Chinese Medicine, Lu'an City 237012, China., Chen X; College of Biotechnology and Pharmaceutical Engineering, West Anhui University, Lu'an City 237012, China; Anhui Province Key Laboratory for Quality Evaluation and Improvement of Traditional Chinese Medicine, Lu'an City 237012, China; Anhui Engineering Technology Center for Conservation and Utilization of Traditional Chinese Medicine Resource, Lu'an City 237012, China; Lu'an City Laboratory for Quality Evaluation and Improvement of Traditional Chinese Medicine, Lu'an City 237012, China. |
المصدر: | Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2024 Aug 15; Vol. 246, pp. 116164. Date of Electronic Publication: 2024 May 05. |
نوع المنشور: | Journal Article; Review |
اللغة: | English |
بيانات الدورية: | Publisher: Elsevier Science Country of Publication: England NLM ID: 8309336 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-264X (Electronic) Linking ISSN: 07317085 NLM ISO Abbreviation: J Pharm Biomed Anal Subsets: MEDLINE |
أسماء مطبوعة: | Publication: <2006->: London : Elsevier Science Original Publication: Oxford ; New York : Pergamon Press, c1983- |
مواضيع طبية MeSH: | Spectroscopy, Near-Infrared*/methods , Flavonoids*/analysis , Prunus*/chemistry , Xanthine Oxidase*/antagonists & inhibitors , Antioxidants*/analysis, Least-Squares Analysis ; Enzyme Inhibitors/analysis ; Enzyme Inhibitors/pharmacology ; China |
مستخلص: | Evaluating the quality of herbal medicine based on the content and activity of its main components is highly beneficial. Developing an eco-friendly determination method has significant application potential. In this study, we propose a new method to simultaneously predict the total flavonoid content (TFC), xanthine oxidase inhibitory (XO) activity, and antioxidant activity (AA) of Prunus mume using near-infrared spectroscopy (NIR). Using the sodium nitrite-aluminum nitrate-sodium hydroxide colorimetric method, uric acid colorimetric method, and 2,2-diphenyl-1-picrylhydrazyl radical (DPPH) free radical scavenging activity as reference methods, we analyzed TFC, XO, and AA in 90 P. mume samples collected from different locations in China. The solid samples were subjected to NIR. By employing spectral preprocessing and optimizing spectral bands, we established a rapid prediction model for TFC, XO, and AA using partial least squares regression (PLS). To improve the model's performance and eliminate irrelevant variables, competitive adaptive reweighted sampling (CARS) was used to calculate the pretreated full spectrum. Evaluation model indicators included the root mean square error of cross-validation (RMSECV) and determination coefficient (R 2 ) values. The TFC, XO, and AA model, combining optimal spectral preprocessing and spectral bands, had RMSECV values of 0.139, 0.117, and 0.121, with R Competing Interests: Declaration of Competing Interest There are no conflicts to declare. (Copyright © 2024. Published by Elsevier B.V.) |
فهرسة مساهمة: | Keywords: Antioxidant activity; Near infrared spectroscopy; PLS regression; Prunus mume; Xanthine oxidase inhibitory |
المشرفين على المادة: | 0 (Flavonoids) EC 1.17.3.2 (Xanthine Oxidase) 0 (Antioxidants) 0 (Enzyme Inhibitors) |
تواريخ الأحداث: | Date Created: 20240522 Date Completed: 20240609 Latest Revision: 20240609 |
رمز التحديث: | 20240610 |
DOI: | 10.1016/j.jpba.2024.116164 |
PMID: | 38776585 |
قاعدة البيانات: | MEDLINE |
تدمد: | 1873-264X |
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DOI: | 10.1016/j.jpba.2024.116164 |