دورية أكاديمية

Association of temperature and absolute humidity with incidence of exercise-induced bronchoconstriction in children.

التفاصيل البيبلوغرافية
العنوان: Association of temperature and absolute humidity with incidence of exercise-induced bronchoconstriction in children.
المؤلفون: Tikkakoski AP; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Reini M; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Sipilä K; Department of Clinical Physiology and Nuclear Medicine, Tampere University Hospital, Tampere, Finland., Kivistö JE; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Allergy Centre, Tampere University Hospital, Tampere, Finland., Karjalainen J; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Allergy Centre, Tampere University Hospital, Tampere, Finland., Kähönen M; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Department of Clinical Physiology and Nuclear Medicine, Tampere University Hospital, Tampere, Finland., Tikkakoski A; Department of Clinical Physiology and Nuclear Medicine, Tampere University Hospital, Tampere, Finland., Lehtimäki L; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Allergy Centre, Tampere University Hospital, Tampere, Finland.
المصدر: Acta paediatrica (Oslo, Norway : 1992) [Acta Paediatr] 2024 Aug; Vol. 113 (8), pp. 1942-1948. Date of Electronic Publication: 2024 May 23.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: Norway NLM ID: 9205968 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1651-2227 (Electronic) Linking ISSN: 08035253 NLM ISO Abbreviation: Acta Paediatr Subsets: MEDLINE
أسماء مطبوعة: Publication: 2007- : Oslo : Wiley-Blackwell
Original Publication: Oslo : Scandinavian University Press, c1992-
مواضيع طبية MeSH: Humidity* , Asthma, Exercise-Induced*/epidemiology , Asthma, Exercise-Induced*/diagnosis , Asthma, Exercise-Induced*/physiopathology , Temperature*, Humans ; Child ; Male ; Female ; Adolescent ; Incidence ; Exercise Test ; Bronchoconstriction
مستخلص: Aim: Exercise test outdoors is widely used to diagnose asthma in children, but it is unclear how much outdoor air factors affect the results.
Methods: We analysed 321 outdoor exercise challenge tests with spirometry in children 6-16 years conducted due to suspicion of asthma or for assessing the effect of medication on asthma. We studied the association of FEV 1 decrease and incidence of exercise-induced bronchoconstriction (EIB) with temperature, relative humidity (RH) and absolute humidity (AH).
Results: Asthma was diagnosed in 57% of the subjects. AH ≥5 g/m 3 , but not RH or temperature, was associated with the EIB incidence (p = 0.035). In multivariable logistic regression, AH ≥5 g/m 3 was negatively associated (OR = 0.51, 95% CI [0.28─0.92], p = 0.026) while obstruction before exercise (OR = 2.11, 95% CI [1.16─3.86], p = 0.015) and IgE-mediated sensitisation were positively associated with EIB (OR = 2.24, 95% CI [1.11─4.51], p = 0.025). AH (r = -0.12, p = 0.028) and temperature (r = -0.13, p = 0.023) correlated with decrease in FEV 1 . In multivariable linear regression, only AH was associated with FEV 1 decrease (coefficient = -0.044, 95% CI [-0.085 to -0.004], p = 0.033).
Conclusion: AH of outdoor air associates with occurrence and severity of EIB in outdoor exercise tests in children. Care should be taken when interpreting negative outdoor exercise test results if AH of air is high.
(© 2024 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.)
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معلومات مُعتمدة: Hengityssairauksien Tutkimussäätiö; Ida Montinin Säätiö; Tampereen Tuberkuloosisäätiö; Suomen Tuberkuloosin Vastustamisyhdistyksen Säätiö
فهرسة مساهمة: Keywords: air humidity; asthma; exercise test; exercise‐induced asthma; pulmonary function tests
تواريخ الأحداث: Date Created: 20240523 Date Completed: 20240711 Latest Revision: 20240711
رمز التحديث: 20240711
DOI: 10.1111/apa.17295
PMID: 38780114
قاعدة البيانات: MEDLINE
الوصف
تدمد:1651-2227
DOI:10.1111/apa.17295