دورية أكاديمية
أعرض في EDS

Independent and joint associations of monocyte to high-density lipoprotein-cholesterol ratio and body mass index with cardiorenal syndrome: insights from NHANES 2003-2020.

التفاصيل البيبلوغرافية
العنوان: Independent and joint associations of monocyte to high-density lipoprotein-cholesterol ratio and body mass index with cardiorenal syndrome: insights from NHANES 2003-2020.
المؤلفون: Lin J; School of Public Health, Zhejiang Chinese Medical University, 548 Binwen Road, Binjiang District, Hangzhou City, 310053, Zhejiang Province, China., Li Z; School of Public Health, Zhejiang Chinese Medical University, 548 Binwen Road, Binjiang District, Hangzhou City, 310053, Zhejiang Province, China., Xu J; School of Public Health, Zhejiang Chinese Medical University, 548 Binwen Road, Binjiang District, Hangzhou City, 310053, Zhejiang Province, China., Pan M; School of Public Health, Zhejiang Chinese Medical University, 548 Binwen Road, Binjiang District, Hangzhou City, 310053, Zhejiang Province, China., Yin T; School of Public Health, Zhejiang Chinese Medical University, 548 Binwen Road, Binjiang District, Hangzhou City, 310053, Zhejiang Province, China., Wang J; Department of Clinical Medicine, School of Medicine, Hangzhou City University, Hangzhou, 310015, China., Sun Q; School of Public Health, Zhejiang Chinese Medical University, 548 Binwen Road, Binjiang District, Hangzhou City, 310053, Zhejiang Province, China., Zheng W; School of Public Health, Zhejiang Chinese Medical University, 548 Binwen Road, Binjiang District, Hangzhou City, 310053, Zhejiang Province, China., Chen R; School of Public Health, Zhejiang Chinese Medical University, 548 Binwen Road, Binjiang District, Hangzhou City, 310053, Zhejiang Province, China. cruc1987@zcmu.edu.cn.
المصدر: Lipids in health and disease [Lipids Health Dis] 2024 May 23; Vol. 23 (1), pp. 153. Date of Electronic Publication: 2024 May 23.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101147696 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-511X (Electronic) Linking ISSN: 1476511X NLM ISO Abbreviation: Lipids Health Dis Subsets: MEDLINE
أسماء مطبوعة: Original Publication: [London] : BioMed Central, 2002-
مواضيع طبية MeSH: Body Mass Index* , Monocytes*/metabolism , Cardio-Renal Syndrome*/blood , Cardio-Renal Syndrome*/epidemiology , Cholesterol, HDL*/blood, Humans ; Male ; Female ; Middle Aged ; Aged ; Risk Factors ; Adult ; Nutrition Surveys ; Odds Ratio ; Logistic Models
مستخلص: Background: With the development of pathophysiology, cardiorenal syndrome (CRS), a complex and severe disease, has received increasing attention. Monocyte to high-density lipoprotein-cholesterol ratio (MHR) and body mass index (BMI) are independent risk factors for cardiovascular diseases, but their association with CRS remains unexplored. This study aims to explore the independent and joint effects of MHR and BMI on CRS.
Methods: We included 42,178 NHANES participants. The determination of CRS referred to the simultaneous presence of cardiovascular disease (identified through self-report) and chronic kidney disease (eGFR < 60 mL/min per 1.73 m²). We employed multivariate weighted logistic regression to evaluate the odds ratio (OR) and 95% confidence interval (CI) for the independent and joint associations of MHR and BMI with CRS. We also conducted restricted cubic spines to explore nonlinear associations.
Results: The prevalence of CRS was 3.45% among all participants. An increase in both MHR and BMI is associated with a higher risk of CRS (MHR: OR = 1.799, 95% CI = 1.520-2.129, P < 0.001, P-trend < 0.001; BMI: OR = 1.037, 95% CI = 1.023-1.051, P < 0.001). Individuals who simultaneously fall into the highest quartile of MHR and have a BMI of 30 or more face the highest risk of CRS compared to those in the lowest MHR quartile with a BMI of less than 25 (OR = 3.45, 95% CI = 2.40-4.98, P < 0.001). However, there is no interactive association between MHR and BMI with CRS.
Conclusions: Higher MHR and BMI are associated with higher odds of CRS. MHR and BMI can serve as tools for early prevention and intervention of CRS, respectively.
(© 2024. The Author(s).)
References: Lipids Health Dis. 2022 Mar 18;21(1):30. (PMID: 35300686)
Nutr Health. 2019 Dec;25(4):245-252. (PMID: 31464165)
Immunobiology. 2012 Dec;217(12):1273-84. (PMID: 22898391)
Ren Fail. 2024 Dec;46(1):2331614. (PMID: 38522954)
Circulation. 2001 Nov 6;104(19):2376-83. (PMID: 11696481)
Curr Atheroscler Rep. 2018 Apr 25;20(6):27. (PMID: 29696385)
Cells. 2022 Jun 20;11(12):. (PMID: 35741108)
Heart Vessels. 2012 Mar;27(2):143-50. (PMID: 21416115)
Eur Heart J. 2020 Jan 7;41(2):221-226. (PMID: 31195408)
J Am Soc Nephrol. 2023 May 1;34(5):793-808. (PMID: 36799882)
J Cell Physiol. 2018 Dec;233(12):9237-9246. (PMID: 30076716)
Adv Chronic Kidney Dis. 2018 Sep;25(5):391-399. (PMID: 30309456)
Cardiol Clin. 2019 Aug;37(3):251-265. (PMID: 31279419)
Circulation. 1989 Jan;79(1):8-15. (PMID: 2642759)
Front Cardiovasc Med. 2022 May 20;9:868658. (PMID: 35669475)
CNS Neurosci Ther. 2023 Jul;29(7):1953-1964. (PMID: 36914580)
Eur Heart J. 2010 Mar;31(6):703-11. (PMID: 20037146)
Curr Drug Targets Immune Endocr Metabol Disord. 2004 Mar;4(1):51-7. (PMID: 15032626)
Eur Heart J. 2014 Feb;35(7):455-69. (PMID: 24164864)
Ann Med. 2016 Aug;48(5):305-12. (PMID: 27087382)
Br J Cardiol. 2021 Apr 22;28(2):22. (PMID: 35747450)
Prog Cardiovasc Dis. 2018 Jul - Aug;61(2):103-113. (PMID: 29964067)
Lipids Health Dis. 2022 Dec 3;21(1):129. (PMID: 36463190)
Nat Rev Nephrol. 2017 Mar;13(3):181-190. (PMID: 28090083)
Kidney Dis (Basel). 2017 Jan;2(4):151-163. (PMID: 28232932)
JAMA Netw Open. 2018 Nov 2;1(7):e183788. (PMID: 30646365)
J Am Soc Nephrol. 2021 Jan;32(1):127-137. (PMID: 33127858)
Nephron. 2021;145(6):604-608. (PMID: 33849028)
Heart Lung Circ. 2016 Nov;25(11):1077-1086. (PMID: 27118231)
Lipids Health Dis. 2019 May 30;18(1):127. (PMID: 31142338)
Ann Intern Med. 2009 May 5;150(9):604-12. (PMID: 19414839)
Adv Nutr. 2019 Jan 1;10(suppl_1):S4-S9. (PMID: 30721956)
Clin Chem. 2022 Mar 4;68(3):461-472. (PMID: 34922334)
Circulation. 2019 Apr 16;139(16):e840-e878. (PMID: 30852913)
Atheroscler Plus. 2023 Apr 18;52:9-17. (PMID: 37193017)
J Am Coll Cardiol. 2014 Jan 7-14;63(1):1-11. (PMID: 24140662)
Int Urol Nephrol. 2014 Aug;46(8):1619-25. (PMID: 24853998)
Curr Opin Lipidol. 2021 Oct 1;32(5):315-322. (PMID: 34374677)
Front Endocrinol (Lausanne). 2023 Mar 28;14:1127425. (PMID: 37056665)
Cardiol J. 2016;23(5):505-512. (PMID: 27296159)
Am J Kidney Dis. 2021 Mar;77(3):427-439. (PMID: 33075388)
JAMA Cardiol. 2018 Apr 1;3(4):280-287. (PMID: 29490333)
معلومات مُعتمدة: 82004143 National Natural Science Foundation of China; 2021ZR02 Foundation of Zhejiang Chinese Medical University; LQ22B070002 Natural Science Foundation of Zhejiang Province
فهرسة مساهمة: Keywords: Body mass index; Cardiorenal syndrome; Monocyte to high-density lipoprotein-cholesterol ratio; NHANES; Public Health
المشرفين على المادة: 0 (Cholesterol, HDL)
تواريخ الأحداث: Date Created: 20240523 Date Completed: 20240524 Latest Revision: 20240526
رمز التحديث: 20240526
مُعرف محوري في PubMed: PMC11112806
DOI: 10.1186/s12944-024-02149-2
PMID: 38783361
قاعدة البيانات: MEDLINE
الوصف
تدمد:1476-511X
DOI:10.1186/s12944-024-02149-2