دورية أكاديمية
أعرض في EDS

Platelet-Rich Fibrin in Non-Surgical Periodontal Therapy: A Split-Mouth Randomized Controlled Clinical Trial.

التفاصيل البيبلوغرافية
العنوان: Platelet-Rich Fibrin in Non-Surgical Periodontal Therapy: A Split-Mouth Randomized Controlled Clinical Trial.
المؤلفون: Parwani SR; Department of Periodontology, V.Y.W.S. Dental College and Hospital, Amravati 444602, India., Thakare KS; Department of Periodontology, V.Y.W.S. Dental College and Hospital, Amravati 444602, India., Kawadkar KP; Department of Periodontology, V.Y.W.S. Dental College and Hospital, Amravati 444602, India., Soni NJ; Department of Periodontology, V.Y.W.S. Dental College and Hospital, Amravati 444602, India., Parwani R; Department of Oral Pathology, V.Y.W.S. Dental College and Hospital, Amravati 444602, India., Dadlani H; Department of Periodontology, Kalka Dental College, Meerut 250103, India.; Principal Consultant, Department of Dentistry, Max Hospital, Gurugram 122001, India., Chaudhary DS; Department of Periodontology, V.Y.W.S. Dental College and Hospital, Amravati 444602, India., Pahuja D; Department of Periodontology, V.Y.W.S. Dental College and Hospital, Amravati 444602, India., Spagnuolo G; Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples Federico II, 80131 Naples, Italy.; Therapeutic Dentistry Department, Institute for Dentistry, Sechenov University, Moscow 119991, Russia., Armogida NG; Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples Federico II, 80131 Naples, Italy.
المصدر: Dentistry journal [Dent J (Basel)] 2024 May 09; Vol. 12 (5). Date of Electronic Publication: 2024 May 09.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101716125 Publication Model: Electronic Cited Medium: Internet ISSN: 2304-6767 (Electronic) Linking ISSN: 23046767 NLM ISO Abbreviation: Dent J (Basel) Subsets: PubMed not MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI AG, [2013]-
مستخلص: This clinical trial investigated the efficacy of platelet-rich fibrin (PRF) as an adjunct to conventional scaling and root planing (SRP) in non-surgical periodontal therapy. In a split-mouth randomized controlled trial with 13 patients and 26 periodontal pocket sites, PRF was inserted in test group pockets alongside SRP, while control group pockets received SRP alone. Measurements at baseline and six weeks included probing pocket depths (PPDs), clinical attachment loss (CAL), gingival recession (GR), the plaque index, and the gingivitis index. The wound healing index was assessed at six weeks. The results show statistically significant improvements in the SRP+PRF group compared to SRP alone, demonstrating a better CAL gain (SRP+PRF group: 2.69 ± 0.63; SRP alone group: 4.15 ± 0.69- p -value: 0.001), PPD reduction (SRP+PRF group: 2.62 ± 0.65; SRP alone group: 3.85 ± 0.80- p -value: 0.001), and GR minimization (SRP+PRF group: 0.46 ± 0.62; SRP alone group: 0.81 ± 0.72- p -value: 0.21). The adjunctive use of PRF enhanced healing, reduced pocket depths, decreased tissue morbidity, and minimized gingival recession. This study concludes that PRF placement is effective in 5-6 mm pockets, potentially reducing the number of periodontal treatment sessions needed for pocket closure.
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فهرسة مساهمة: Keywords: periodontal pocket; periodontitis; platelet-rich fibrin; scaling and root planing
تواريخ الأحداث: Date Created: 20240524 Latest Revision: 20240526
رمز التحديث: 20240526
مُعرف محوري في PubMed: PMC11120449
DOI: 10.3390/dj12050135
PMID: 38786533
قاعدة البيانات: MEDLINE
الوصف
تدمد:2304-6767
DOI:10.3390/dj12050135