دورية أكاديمية
أعرض في EDS

Prevalence of T-2 Toxin in the Food and Beverages of Residents Living in a Kashin-Beck-Disease Area of Qamdo, Tibet.

التفاصيل البيبلوغرافية
العنوان: Prevalence of T-2 Toxin in the Food and Beverages of Residents Living in a Kashin-Beck-Disease Area of Qamdo, Tibet.
المؤلفون: Jiang T; National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050, China.; Key Laboratory of Public Nutrition and Health, National Health Commission of the People's Republic of China, Beijing 100050, China., Yan J; Shenzhen Chronic Disease Prevention and Treatment Center, Shenzhen 518000, China., Tan H; Shenzhen Chronic Disease Prevention and Treatment Center, Shenzhen 518000, China., Pu Z; Center for Disease Control and Prevention, Luolong County, Chamdo 855400, China., Wang O; National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050, China.; Key Laboratory of Public Nutrition and Health, National Health Commission of the People's Republic of China, Beijing 100050, China., Liu T; Shenzhen Chronic Disease Prevention and Treatment Center, Shenzhen 518000, China., Chen Z; The Department of Orthopedics & Traumatology, Peking University People's Hospital, Beijing 100044, China., Gao J; The Department of Orthopedics & Traumatology, Peking University People's Hospital, Beijing 100044, China., Wang J; Shenzhen Chronic Disease Prevention and Treatment Center, Shenzhen 518000, China., Lin J; The Department of Orthopedics & Traumatology, Peking University People's Hospital, Beijing 100044, China., Huo J; National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050, China.; Key Laboratory of Public Nutrition and Health, National Health Commission of the People's Republic of China, Beijing 100050, China., Huang J; National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing 100050, China.; Key Laboratory of Public Nutrition and Health, National Health Commission of the People's Republic of China, Beijing 100050, China.
المصدر: Nutrients [Nutrients] 2024 May 11; Vol. 16 (10). Date of Electronic Publication: 2024 May 11.
نوع المنشور: Journal Article
اللغة: English
بيانات الدورية: Publisher: MDPI Publishing Country of Publication: Switzerland NLM ID: 101521595 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6643 (Electronic) Linking ISSN: 20726643 NLM ISO Abbreviation: Nutrients Subsets: MEDLINE
أسماء مطبوعة: Original Publication: Basel, Switzerland : MDPI Publishing
مواضيع طبية MeSH: Kashin-Beck Disease*/epidemiology , Kashin-Beck Disease*/blood , T-2 Toxin*/blood , T-2 Toxin*/analogs & derivatives , T-2 Toxin*/analysis , Selenium*/blood, Humans ; Tibet/epidemiology ; Female ; Male ; Adult ; Middle Aged ; Prevalence ; Beverages ; Food Contamination/analysis ; Tea/chemistry ; Diet/statistics & numerical data ; Case-Control Studies ; Diet Surveys
مستخلص: It has been strongly suggested that selenium deficiency and T-2 toxin contamination have a strong relationship with the occurrence and development of Kashin-Beck disease (KBD). In order to provide information for understanding the high prevalence of KBD in Tibet, this study collected the responses to a cubital venous blood and dietary questionnaire of 125 subjects including 75 KBD patients and 50 healthy controls in a KBD-prevalent county (Luolong County) in Tibet, China. A total of 10 household local families were randomly selected in this area, and local diet samples of brick tea, Zanba powder, milk residue, and hulless Barley were collected from these residents. Selenium content in blood was detected by inductively coupled plasma mass spectrometry (ICP-MS). The T-2 toxin contamination level in food sample was assayed using an ELISA kit. The selenium levels of patients and controls were 42.0 ± 19.8 and 56.06 ± 22.4 μg/L, respectively. The serum selenium level in controls was higher than that in patients, but there was no significant difference, and the serum selenium level both in patients and controls in Tibet was lower than the normal range. The results of the dietary survey showed that the number of respondents who consumed butter tea was large; 46.67% of patients indicated that they drank buttered tea every day, which was significantly higher than in controls. The contents of T-2 toxin in Zanba powder, milk residue, hulless barley and drinking water samples were below the detection limit (0.05 μg/kg); this result was labeled Tr. Unexpectedly, the contents of T-2 toxin in brick tea were higher, with average levels of 424 ± 56 μg/kg in Detong village and 396 ± 24 μg/kg in Langcuo village. For the first time, we report the presence of an extremely high concentration of T-2 toxin in brick tea of Tibet.
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معلومات مُعتمدة: SPSYYC2020-006 National Health Commission of the People's Republic of China- Food Safety Standards, Monitor-ing and Evaluation Department[KBD Patients Nutrition and Dietary Guidance]
فهرسة مساهمة: Keywords: Kashin–Beck disease; T-2 toxin; Tibet; brick tea; selenium
المشرفين على المادة: I3FL5NM3MO (T-2 Toxin)
H6241UJ22B (Selenium)
0 (Tea)
تواريخ الأحداث: Date Created: 20240525 Date Completed: 20240525 Latest Revision: 20240527
رمز التحديث: 20240527
مُعرف محوري في PubMed: PMC11123768
DOI: 10.3390/nu16101449
PMID: 38794687
قاعدة البيانات: MEDLINE
الوصف
تدمد:2072-6643
DOI:10.3390/nu16101449