دورية أكاديمية
Glyphosate contamination of drinking water and the occurrence of oxidative stress: Exposure assessment to rural Brazilian populations.
| العنوان: | Glyphosate contamination of drinking water and the occurrence of oxidative stress: Exposure assessment to rural Brazilian populations. |
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| المؤلفون: | Nunes RFN; Laboratory of Toxicant and Drug Analyses, Federal University of Alfenas - Unifal-MG, Gabriel Monteiro da Silva St. 700, Alfenas, MG 37130-000, Brazil. Electronic address: isarita.sakakibara@unifal-mg.edu.br., Marciano LPA; Laboratory of Toxicant and Drug Analyses, Federal University of Alfenas - Unifal-MG, Gabriel Monteiro da Silva St. 700, Alfenas, MG 37130-000, Brazil., Oliveira GS; Laboratory of Toxicant and Drug Analyses, Federal University of Alfenas - Unifal-MG, Gabriel Monteiro da Silva St. 700, Alfenas, MG 37130-000, Brazil., Cardoso NS; Laboratory of Clinical and Experimental Biochemistry Research, Federal University of Alfenas - Unifal-MG, Gabriel Monteiro da Silva St. 700, Alfenas, MG 37130-000, Brazil., Paula FBA; Laboratory of Clinical and Experimental Biochemistry Research, Federal University of Alfenas - Unifal-MG, Gabriel Monteiro da Silva St. 700, Alfenas, MG 37130-000, Brazil., Sarpa M; Laboratory of Environmental Occupational Toxicology and Cancer Surveillance, National Cancer Institute - INCA-RJ, Marquês de Pombal St. 125, Rio de Janeiro, RJ 20230-240, Brazil., Martins I; Laboratory of Toxicant and Drug Analyses, Federal University of Alfenas - Unifal-MG, Gabriel Monteiro da Silva St. 700, Alfenas, MG 37130-000, Brazil. Electronic address: isarita.sakakibara@unifal-mg.edu.br. |
| المصدر: | Environmental toxicology and pharmacology [Environ Toxicol Pharmacol] 2024 Jun; Vol. 108, pp. 104476. Date of Electronic Publication: 2024 May 23. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Science B.V Country of Publication: Netherlands NLM ID: 9612020 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7077 (Electronic) Linking ISSN: 13826689 NLM ISO Abbreviation: Environ Toxicol Pharmacol Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Amsterdam : Elsevier Science B.V., c1996- |
| مواضيع طبية MeSH: | Glyphosate* , Glycine*/analogs & derivatives , Glycine*/toxicity , Oxidative Stress*/drug effects , Water Pollutants, Chemical*/toxicity , Water Pollutants, Chemical*/analysis , Rural Population* , Drinking Water*/analysis , Drinking Water*/chemistry , Herbicides*/toxicity, Brazil ; Humans ; Adult ; Male ; Female ; Middle Aged ; Catalase/blood ; Superoxide Dismutase/metabolism ; Superoxide Dismutase/blood ; Environmental Exposure/analysis ; Environmental Exposure/adverse effects ; Lipid Peroxidation/drug effects ; Young Adult ; Aged |
| مستخلص: | Studies reported that continuous application of glyphosate can cause disturbance in aquatic/terrestrial environments. As such, the objective of this study is to discuss the risk of exposure to the herbicide in drinking water and to assess the oxidative stress in the consumers rural populations of Casimiro de Abreu/ RJ and Paraguaçu/ MG, Brazil. For this, water samples (n=69) were analysed from the home of volunteers, by FMOC derivatizing- LC-FLD method. The oxidative stress was analysed determining lipid peroxidation (MAD) and defense enzymes (SOD and CAT) in serum samples from rural population (n=42) compared to urban residents (n= 42). Results of the analysis from drinking water, despite the low and moderate risk, by the hazard quotient (HQ), revealed that the population is environmentally exposed to the glyphosate. The relevant findings showed that is important to implement monitoring/ biomonitoring programs to prevent pollution and toxic effects in the rural populations. Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (Copyright © 2024 Elsevier B.V. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Drinking water; Exposure assessment; Farmers; Glyphosate and AMPA |
| المشرفين على المادة: | 4632WW1X5A (Glyphosate) TE7660XO1C (Glycine) 0 (Water Pollutants, Chemical) 0 (Drinking Water) 0 (Herbicides) EC 1.11.1.6 (Catalase) EC 1.15.1.1 (Superoxide Dismutase) |
| تواريخ الأحداث: | Date Created: 20240525 Date Completed: 20240604 Latest Revision: 20240604 |
| رمز التحديث: | 20240605 |
| DOI: | 10.1016/j.etap.2024.104476 |
| PMID: | 38796121 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 1872-7077 |
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| DOI: | 10.1016/j.etap.2024.104476 |