دورية أكاديمية
A critical eye on metopic craniosynostosis: A retrospective study assessing orbital dysmorphology as a marker of disease.
| العنوان: | A critical eye on metopic craniosynostosis: A retrospective study assessing orbital dysmorphology as a marker of disease. |
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| المؤلفون: | Barrero CE; Division of Plastic, Reconstructive and Oral Surgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Pontell ME; Division of Plastic, Reconstructive and Oral Surgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Naidu K; Division of Plastic, Reconstructive and Oral Surgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Wagner CS; Division of Plastic, Reconstructive and Oral Surgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Salinero LK; Division of Plastic, Reconstructive and Oral Surgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Swanson JW; Division of Plastic, Reconstructive and Oral Surgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Taylor JA; Division of Plastic, Reconstructive and Oral Surgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Bartlett SP; Division of Plastic, Reconstructive and Oral Surgery, Children's Hospital of Philadelphia, Philadelphia, PA, USA. Electronic address: bartletts@chop.edu. |
| المصدر: | Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery [J Craniomaxillofac Surg] 2024 Jul; Vol. 52 (7), pp. 865-871. Date of Electronic Publication: 2024 May 03. |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: Scotland NLM ID: 8704309 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-4119 (Electronic) Linking ISSN: 10105182 NLM ISO Abbreviation: J Craniomaxillofac Surg Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Edinburgh : Elsevier Original Publication: Stuttgart ; New York : Thieme, [c1986- |
| مواضيع طبية MeSH: | Craniosynostoses*/diagnostic imaging , Craniosynostoses*/surgery , Orbit*/diagnostic imaging , Orbit*/pathology , Tomography, X-Ray Computed*/methods , Imaging, Three-Dimensional*/methods, Humans ; Retrospective Studies ; Male ; Female ; Infant ; Child, Preschool ; Case-Control Studies |
| مستخلص: | This investigation sought to ascertain whether orbital morphology could predict genuine metopic craniosynostosis (MCS). The study retrospectively analyzed preoperative three-dimensional computed tomography (3D-CT) scans of patients who underwent surgical correction for MCS. MCS severity was evaluated using the interfrontal angle (IFA). Orbital dysmorphology was assessed based on multiple angles, including supraorbital notches and nasion (SNS), infraorbital foramina and nasion (INI), zygomaticofrontal suture-supraorbital notch-dacryon (ZSD), and orbital long axis (OLA). Results were juxtaposed against age/gender-matched controls and individuals with non-synostotic metopic ridge (MR). The study included 177 patients: 68 MCS, 35 MR, and 74 control subjects. All orbital measurements exhibited significant differences across groups. IFA demonstrated a strong association with all orbital measurements, particularly SNS (B = 0.79, p < 0.001). SNS showed the highest area under the curve among orbital measurements (0.89). Using a 95% sensitivity threshold, the optimal diagnostic angle for SNS was 129.23° (specificity 54%, sensitivity 96%). These findings suggest a correlation between orbital dysmorphology and trigonocephaly severity. The observed dysmorphology manifested in a superomedially accentuated rotational pattern. Importantly, SNS angle predicted MCS, with an angle greater than 130° indicating <5% likelihood of MCS diagnosis. The simplicity of measuring SNS angle on any 3D-CT scan highlights its practical use for assisting with MCS diagnosis. Competing Interests: Declaration of competing interest JAT is a co-founder of Ostiio, LLC. JWS has developed educational content for Synthes. All other authors have no financial conflicts of interest to disclose. (Copyright © 2024 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Craniometrics; Metopic craniosynostosis; Orbit; Radiographic imaging |
| تواريخ الأحداث: | Date Created: 20240525 Date Completed: 20240721 Latest Revision: 20240721 |
| رمز التحديث: | 20240722 |
| DOI: | 10.1016/j.jcms.2024.04.015 |
| PMID: | 38796332 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 1878-4119 |
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| DOI: | 10.1016/j.jcms.2024.04.015 |