دورية أكاديمية
Vasodilator reactive oxygen species ameliorate perturbed myocardial oxygen delivery in exercising swine with multiple comorbidities.
| العنوان: | Vasodilator reactive oxygen species ameliorate perturbed myocardial oxygen delivery in exercising swine with multiple comorbidities. |
|---|---|
| المؤلفون: | van Drie RWA; Division of Experimental Cardiology, Department of Cardiology, Thoraxcenter, Erasmus University Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.; Laboratory of Vascular Medicine, Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands., van de Wouw J; Division of Experimental Cardiology, Department of Cardiology, Thoraxcenter, Erasmus University Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands., Zandbergen LM; Division of Experimental Cardiology, Department of Cardiology, Thoraxcenter, Erasmus University Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands.; Walter Brendel Center of Experimental Medicine (WBex), University Clinic Munich, 81377 LMU, Munich, Germany., Dehairs J; Laboratory of Lipid Metabolism and Cancer, Department of Oncology, KU Leuven-University of Leuven, Leuven, Belgium., Swinnen JV; Laboratory of Lipid Metabolism and Cancer, Department of Oncology, KU Leuven-University of Leuven, Leuven, Belgium., Mulder MT; Laboratory of Vascular Medicine, Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands., Verhaar MC; Department of Nephrology and Hypertension, University Medical Center Utrecht, Utrecht, The Netherlands., MaassenVanDenBrink A; Laboratory of Vascular Medicine, Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, The Netherlands., Duncker DJ; Division of Experimental Cardiology, Department of Cardiology, Thoraxcenter, Erasmus University Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands., Sorop O; Division of Experimental Cardiology, Department of Cardiology, Thoraxcenter, Erasmus University Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands., Merkus D; Division of Experimental Cardiology, Department of Cardiology, Thoraxcenter, Erasmus University Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands. d.merkus@erasmusmc.nl.; Walter Brendel Center of Experimental Medicine (WBex), University Clinic Munich, 81377 LMU, Munich, Germany. d.merkus@erasmusmc.nl.; Center for Cardiovascular Research (DZHK), Munich Heart Alliance (MHA), Partner Site Munich, 81377, Munich, Germany. d.merkus@erasmusmc.nl.; Interfaculty Center for Endocrine and Cardiovascular Disease Network Modelling and Clinical Transfer (ICONLMU), University Clinic Munich, LMU, Munich, Germany. d.merkus@erasmusmc.nl. |
| المصدر: | Basic research in cardiology [Basic Res Cardiol] 2024 May 25. Date of Electronic Publication: 2024 May 25. |
| Publication Model: | Ahead of Print |
| نوع المنشور: | Journal Article |
| اللغة: | English |
| بيانات الدورية: | Publisher: Steinkopff Country of Publication: Germany NLM ID: 0360342 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1435-1803 (Electronic) Linking ISSN: 03008428 NLM ISO Abbreviation: Basic Res Cardiol Subsets: MEDLINE |
| أسماء مطبوعة: | Original Publication: Darmstadt, Steinkopff. |
| مستخلص: | Multiple common cardiovascular comorbidities produce coronary microvascular dysfunction. We previously observed in swine that a combination of diabetes mellitus (DM), high fat diet (HFD) and chronic kidney disease (CKD) induced systemic inflammation, increased oxidative stress and produced coronary endothelial dysfunction, altering control of coronary microvascular tone via loss of NO bioavailability, which was associated with an increase in circulating endothelin (ET). In the present study, we tested the hypotheses that (1) ROS scavenging and (2) ET (© 2024. The Author(s).) |
| References: | Aribas E, Roeters van Lennep JE, Elias-Smale SE, Piek JJ, Roos M, Ahmadizar F, Arshi B, Duncker DJ, Appelman Y, Kavousi M (2022) Prevalence of microvascular angina among patients with stable symptoms in the absence of obstructive coronary artery disease: a systematic review. Cardiovasc Res 118:763–771. https://doi.org/10.1093/cvr/cvab061. (PMID: 10.1093/cvr/cvab06133677526) Batenburg WW, Garrelds IM, van Kats JP, Saxena PR, Danser AH (2004) Mediators of bradykinin-induced vasorelaxation in human coronary microarteries. Hypertension 43:488–492. https://doi.org/10.1161/01.HYP.0000110904.95771.26. (PMID: 10.1161/01.HYP.0000110904.95771.2614691197) Battelli MG, Polito L, Bortolotti M, Bolognesi A (2016) Xanthine oxidoreductase-derived reactive species: physiological and pathological effects. Oxid Med Cell Longev 2016:3527579. https://doi.org/10.1155/2016/3527579. (PMID: 10.1155/2016/352757926823950) Beyer AM, Zinkevich N, Miller B, Liu Y, Wittenburg AL, Mitchell M, Galdieri R, Sorokin A, Gutterman DD (2017) Transition in the mechanism of flow-mediated dilation with aging and development of coronary artery disease. Basic Res Cardiol 112:5. https://doi.org/10.1007/s00395-016-0594-x. (PMID: 10.1007/s00395-016-0594-x27995364) Boengler K, Schulz R, Heusch G (2009) Loss of cardioprotection with ageing. Cardiovasc Res 83:247–261. https://doi.org/10.1093/cvr/cvp033. (PMID: 10.1093/cvr/cvp03319176601) Borbouse L, Dick GM, Payne GA, Berwick ZC, Neeb ZP, Alloosh M, Bratz IN, Sturek M, Tune JD (2010) Metabolic syndrome reduces the contribution of K+ channels to ischemic coronary vasodilation. Am J Physiol Heart Circ Physiol 298:H1182-1189. https://doi.org/10.1152/ajpheart.00888.2009. (PMID: 10.1152/ajpheart.00888.2009201184082853415) Byon CH, Heath JM, Chen Y (2016) Redox signaling in cardiovascular pathophysiology: a focus on hydrogen peroxide and vascular smooth muscle cells. Redox Biol 9:244–253. https://doi.org/10.1016/j.redox.2016.08.015. (PMID: 10.1016/j.redox.2016.08.015275914035011184) Byrne NJ, Rajasekaran NS, Abel ED, Bugger H (2021) Therapeutic potential of targeting oxidative stress in diabetic cardiomyopathy. Free Radic Biol Med 169:317–342. https://doi.org/10.1016/j.freeradbiomed.2021.03.046. (PMID: 10.1016/j.freeradbiomed.2021.03.046339100938285002) Camici PG, Tschope C, Di Carli MF, Rimoldi O, Van Linthout S (2020) Coronary microvascular dysfunction in hypertrophy and heart failure. Cardiovasc Res 116:806–816. https://doi.org/10.1093/cvr/cvaa023. (PMID: 10.1093/cvr/cvaa02331999329) Cantu-Medellin N, Kelley EE (2013) Xanthine oxidoreductase-catalyzed reactive species generation: a process in critical need of reevaluation. Redox Biol 1:353–358. https://doi.org/10.1016/j.redox.2013.05.002. (PMID: 10.1016/j.redox.2013.05.002240241713757702) Chade AR, Sitz R, Kelty TJ, McCarthy E, Tharp DL, Rector RS, Eirin A (2024) Chronic kidney disease and left ventricular diastolic dysfunction (CKD-LVDD) alter cardiac expression of mitochondria-related genes in swine. Transl Res 267:67–78. https://doi.org/10.1016/j.trsl.2023.12.004. (PMID: 10.1016/j.trsl.2023.12.00438262578) Choi S, Snider AJ (2015) Sphingolipids in high fat diet and obesity-related diseases. Mediators Inflamm 2015:520618. https://doi.org/10.1155/2015/520618. (PMID: 10.1155/2015/520618266486644663345) Clarke CJ, Guthrie JM, Hannun YA (2008) Regulation of neutral sphingomyelinase-2 (nSMase2) by tumor necrosis factor-alpha involves protein kinase C-delta in lung epithelial cells. Mol Pharmacol 74:1022–1032. https://doi.org/10.1124/mol.108.046250. (PMID: 10.1124/mol.108.04625018653803) Cohen KE, Katunaric B, Schulz ME, SenthilKumar G, Young MS, Mace JE, Freed JK (2022) Role of adiponectin receptor 1 in promoting nitric oxide-mediated flow-induced dilation in the human microvasculature. Front Pharmacol 13:875900. https://doi.org/10.3389/fphar.2022.875900. (PMID: 10.3389/fphar.2022.875900354445449014203) Corban MT, Prasad A, Gulati R, Lerman LO, Lerman A (2021) Sex-specific differences in coronary blood flow and flow velocity reserve in symptomatic patients with non-obstructive disease. EuroIntervention 16:1079–1084. https://doi.org/10.4244/EIJ-D-19-00520. (PMID: 10.4244/EIJ-D-19-00520315891449724856) Crivelli SM, van Kruining D, Luo Q, Stevens JAA, Giovagnoni C, Paulus A, Bauwens M, Berkes D, de Vries HE, Mulder MT, Walter J, Waelkens E, Derua R, Swinnen JV, Dehairs J, Mottaghy FM, Losen M, Bieberich E, Martinez-Martinez P (2020) Ceramide analog [(18)F]F-HPA-12 detects sphingolipid disbalance in the brain of Alzheimer’s disease transgenic mice by functioning as a metabolic probe. Sci Rep 10:19354. https://doi.org/10.1038/s41598-020-76335-4. (PMID: 10.1038/s41598-020-76335-4331688617652882) Cruz-Lopez EO, Ye D, Stolk DG, Clahsen-van Groningen MC, van Veghel R, Garrelds IM, Poglitsch M, Domenig O, Alipour Symakani RS, Merkus D, Verdonk K, Jan Danser AH (2024) Combining renin-angiotensin system blockade and sodium-glucose cotransporter-2 inhibition in experimental diabetes results in synergistic beneficial effects. J Hypertens 42:883–892. https://doi.org/10.1097/HJH.0000000000003633. (PMID: 10.1097/HJH.000000000000363338088400) Davenport AP, Hyndman KA, Dhaun N, Southan C, Kohan DE, Pollock JS, Pollock DM, Webb DJ, Maguire JJ (2016) Endothelin. Pharmacol Rev 68:357–418. https://doi.org/10.1124/pr.115.011833. (PMID: 10.1124/pr.115.011833269562454815360) de Lannoy LM, Danser AH, van Kats JP, Schoemaker RG, Saxena PR, Schalekamp MA (1997) Renin-angiotensin system components in the interstitial fluid of the isolated perfused rat heart. Local production of angiotensin I. Hypertension 29:1240–1251. https://doi.org/10.1161/01.hyp.29.6.1240. (PMID: 10.1161/01.hyp.29.6.12409180624) de Mello AH, Costa AB, Engel JDG, Rezin GT (2018) Mitochondrial dysfunction in obesity. Life Sci 192:26–32. https://doi.org/10.1016/j.lfs.2017.11.019. (PMID: 10.1016/j.lfs.2017.11.01929155300) De Wijs-Meijler DP, Stam K, van Duin RW, Verzijl A, Reiss IK, Duncker DJ, Merkus D (2016) Surgical placement of catheters for long-term cardiovascular exercise testing in swine. J Vis Exp:e53772. https://doi.org/10.3791/53772. Dick GM, Bratz IN, Borbouse L, Payne GA, Dincer UD, Knudson JD, Rogers PA, Tune JD (2008) Voltage-dependent K+ channels regulate the duration of reactive hyperemia in the canine coronary circulation. Am J Physiol Heart Circ Physiol 294:H2371-2381. https://doi.org/10.1152/ajpheart.01279.2007. (PMID: 10.1152/ajpheart.01279.200718375717) Dubois-Deruy E, Peugnet V, Turkieh A, Pinet F (2020) Oxidative stress in cardiovascular diseases. Antioxidants 9:864. https://doi.org/10.3390/antiox9090864. (PMID: 10.3390/antiox9090864329379507554855) Dwenger MM, Raph SM, Reyzer ML, Lisa Manier M, Riggs DW, Wohl ZB, Ohanyan V, Mack G, Pucci T, Moore JB, Hill BG, Chilian WM, Caprioli RM, Bhatnagar A, Nystoriak MA (2022) Pyridine nucleotide redox potential in coronary smooth muscle couples myocardial blood flow to cardiac metabolism. Nat Commun 13:2051. https://doi.org/10.1038/s41467-022-29745-z. (PMID: 10.1038/s41467-022-29745-z354406329018695) Eickelmann C, Lieder HR, Sturek M, Heusch G, Kleinbongard P (2024) Differences in vasomotor function of mesenteric arteries between Ossabaw minipigs with predisposition to metabolic syndrome and Gottingen minipigs. Am J Physiol Heart Circ Physiol 326:H408–H417. https://doi.org/10.1152/ajpheart.00719.2023. (PMID: 10.1152/ajpheart.00719.202338133620) Eirin A, Chade AR (2023) Cardiac epigenetic changes in VEGF signaling genes associate with myocardial microvascular rarefaction in experimental chronic kidney disease. Am J Physiol Heart Circ Physiol 324:H14–H25. https://doi.org/10.1152/ajpheart.00522.2022. (PMID: 10.1152/ajpheart.00522.202236367693) Erdei N, Toth A, Pasztor ET, Papp Z, Edes I, Koller A, Bagi Z (2006) High-fat diet-induced reduction in nitric oxide-dependent arteriolar dilation in rats: role of xanthine oxidase-derived superoxide anion. Am J Physiol Heart Circ Physiol 291:H2107-2115. https://doi.org/10.1152/ajpheart.00389.2006. (PMID: 10.1152/ajpheart.00389.200616798827) Ferdinandy P, Andreadou I, Baxter GF, Botker HE, Davidson SM, Dobrev D, Gersh BJ, Heusch G, Lecour S, Ruiz-Meana M, Zuurbier CJ, Hausenloy DJ, Schulz R (2023) Interaction of cardiovascular nonmodifiable risk factors, comorbidities and comedications with ischemia/reperfusion injury and cardioprotection by pharmacological treatments and ischemic conditioning. Pharmacol Rev 75:159–216. https://doi.org/10.1124/pharmrev.121.000348. (PMID: 10.1124/pharmrev.121.000348367530499832381) Franssen C, Chen S, Unger A, Korkmaz HI, De Keulenaer GW, Tschope C, Leite-Moreira AF, Musters R, Niessen HW, Linke WA, Paulus WJ, Hamdani N (2016) Myocardial microvascular inflammatory endothelial activation in heart failure with preserved ejection fraction. JACC Heart Fail 4:312–324. https://doi.org/10.1016/j.jchf.2015.10.007. (PMID: 10.1016/j.jchf.2015.10.00726682792) Freed JK, Beyer AM, LoGiudice JA, Hockenberry JC, Gutterman DD (2014) Ceramide changes the mediator of flow-induced vasodilation from nitric oxide to hydrogen peroxide in the human microcirculation. Circ Res 115:525–532. https://doi.org/10.1161/CIRCRESAHA.115.303881. (PMID: 10.1161/CIRCRESAHA.115.303881249206984640193) Gaggini M, Ndreu R, Michelucci E, Rocchiccioli S, Vassalle C (2022) Ceramides as mediators of oxidative stress and inflammation in cardiometabolic disease. Int J Mol Sci 23:2719. https://doi.org/10.3390/ijms23052719. (PMID: 10.3390/ijms23052719352698618911014) Giacco F, Brownlee M (2010) Oxidative stress and diabetic complications. Circ Res 107:1058–1070. https://doi.org/10.1161/CIRCRESAHA.110.223545. (PMID: 10.1161/CIRCRESAHA.110.223545210307232996922) Hattori Y, Suzuki M, Hattori S, Kasai K (2003) Globular adiponectin upregulates nitric oxide production in vascular endothelial cells. Diabetologia 46:1543–1549. https://doi.org/10.1007/s00125-003-1224-3. (PMID: 10.1007/s00125-003-1224-314551684) Heinonen I, Sorop O, van Dalen BM, Wust RCI, van de Wouw J, de Beer VJ, Octavia Y, van Duin RWB, Hoogstrate Y, Blonden L, Alkio M, Anttila K, Stubbs A, van der Velden J, Merkus D, Duncker DJ (2020) Cellular, mitochondrial and molecular alterations associate with early left ventricular diastolic dysfunction in a porcine model of diabetic metabolic derangement. Sci Rep 10:13173. https://doi.org/10.1038/s41598-020-68637-4. (PMID: 10.1038/s41598-020-68637-4327645697413251) Heitzer T, Krohn K, Albers S, Meinertz T (2000) Tetrahydrobiopterin improves endothelium-dependent vasodilation by increasing nitric oxide activity in patients with Type II diabetes mellitus. Diabetologia 43:1435–1438. https://doi.org/10.1007/s001250051551. (PMID: 10.1007/s00125005155111126415) Heusch G (2022) Coronary blood flow in heart failure: cause, consequence and bystander. Basic Res Cardiol 117:1. https://doi.org/10.1007/s00395-022-00909-8. (PMID: 10.1007/s00395-022-00909-8350249698758654) Heusch G, Andreadou I, Bell R, Bertero E, Botker HE, Davidson SM, Downey J, Eaton P, Ferdinandy P, Gersh BJ, Giacca M, Hausenloy DJ, Ibanez B, Krieg T, Maack C, Schulz R, Sellke F, Shah AM, Thiele H, Yellon DM, Di Lisa F (2023) Health position paper and redox perspectives on reactive oxygen species as signals and targets of cardioprotection. Redox Biol 67:102894. https://doi.org/10.1016/j.redox.2023.102894. (PMID: 10.1016/j.redox.2023.1028943783935510590874) Holland WL, Miller RA, Wang ZV, Sun K, Barth BM, Bui HH, Davis KE, Bikman BT, Halberg N, Rutkowski JM, Wade MR, Tenorio VM, Kuo MS, Brozinick JT, Zhang BB, Birnbaum MJ, Summers SA, Scherer PE (2011) Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin. Nat Med 17:55–63. https://doi.org/10.1038/nm.2277. (PMID: 10.1038/nm.227721186369) Jespersen L, Hvelplund A, Abildstrom SZ, Pedersen F, Galatius S, Madsen JK, Jorgensen E, Kelbaek H, Prescott E (2012) Stable angina pectoris with no obstructive coronary artery disease is associated with increased risks of major adverse cardiovascular events. Eur Heart J 33:734–744. https://doi.org/10.1093/eurheartj/ehr331. (PMID: 10.1093/eurheartj/ehr33121911339) Johnson BD, Shaw LJ, Pepine CJ, Reis SE, Kelsey SF, Sopko G, Rogers WJ, Mankad S, Sharaf BL, Bittner V, Bairey Merz CN (2006) Persistent chest pain predicts cardiovascular events in women without obstructive coronary artery disease: results from the NIH-NHLBI-sponsored Women’s Ischaemia Syndrome Evaluation (WISE) study. Eur Heart J 27:1408–1415. https://doi.org/10.1093/eurheartj/ehl040. (PMID: 10.1093/eurheartj/ehl04016720691) Kang LS, Chen B, Reyes RA, Leblanc AJ, Teng B, Mustafa SJ, Muller-Delp JM (2011) Aging and estrogen alter endothelial reactivity to reactive oxygen species in coronary arterioles. Am J Physiol Heart Circ Physiol 300:H2105-2115. https://doi.org/10.1152/ajpheart.00349.2010. (PMID: 10.1152/ajpheart.00349.2010214413093119103) Katunaric B, Cohen KE, Beyer AM, Gutterman DD, Freed JK (2021) Sweat the small stuff: the human microvasculature and heart disease. Microcirculation 28:e12658. https://doi.org/10.1111/micc.12658. (PMID: 10.1111/micc.1265832939881) Kikas P, Chalikias G, Tziakas D (2018) Cardiovascular implications of sphingomyelin presence in biological membranes. Eur Cardiol 13:42–45. https://doi.org/10.15420/ecr.2017:20:3. (PMID: 10.15420/ecr.2017:20:3303104706159463) Kleinbongard P, Lieder H, Skyschally A, Heusch G (2023) No sex-related differences in infarct size, no-reflow, and protection by ischaemic pre-conditioning in Gottingen minipigs. Cardiovasc Res 119:561–570. https://doi.org/10.1093/cvr/cvac062. (PMID: 10.1093/cvr/cvac06235426434) Kleinbongard P, Lieder HR, Skyschally A, Heusch G (2023) No robust reduction of infarct size and no-reflow by metoprolol pretreatment in adult Gottingen minipigs. Basic Res Cardiol 118:23. https://doi.org/10.1007/s00395-023-00993-4. (PMID: 10.1007/s00395-023-00993-43728924710250284) Kodydkova J, Vavrova L, Kocik M, Zak A (2014) Human catalase, its polymorphisms, regulation and changes of its activity in different diseases. Folia Biol (Praha) 60:153–167. (PMID: 25152049) Kostov K (2021) The causal relationship between Endothelin-1 and hypertension: focusing on endothelial dysfunction, arterial stiffness, vascular remodeling, and blood pressure regulation. Life (Basel) 11:986. https://doi.org/10.3390/life11090986. (PMID: 10.3390/life1109098634575135) Kwan AC, Wei J, Ouyang D, Ebinger JE, Merz CNB, Berman D, Cheng S (2023) Sex differences in contributors to coronary microvascular dysfunction. Front Cardiovasc Med 10:1085914. https://doi.org/10.3389/fcvm.2023.1085914. (PMID: 10.3389/fcvm.2023.1085914367605569902873) Leong D, Tjoe B, Zarrini P, Cook-Wiens G, Wei J, Shufelt CL, Pepine CJ, Handberg EM, Reis SE, Reichek N, Bittner V, Kelsey SF, Marpuri RS, Sopko G, Merz CNB (2021) Risk factors for heart failure in women with ischemia and no obstructive coronary artery disease. Am Heart J Plus Cardiol Res Pract 8:100035. https://doi.org/10.1016/j.ahjo.2021.100035. (PMID: 10.1016/j.ahjo.2021.100035) Liu Y, Gutterman DD (2002) Oxidative stress and potassium channel function. Clin Exp Pharmacol Physiol 29:305–311. https://doi.org/10.1046/j.1440-1681.2002.03649.x. (PMID: 10.1046/j.1440-1681.2002.03649.x11985541) Liu Y, Zhao H, Li H, Kalyanaraman B, Nicolosi AC, Gutterman DD (2003) Mitochondrial sources of H2O2 generation play a key role in flow-mediated dilation in human coronary resistance arteries. Circ Res 93:573–580. https://doi.org/10.1161/01.RES.0000091261.19387.AE. (PMID: 10.1161/01.RES.0000091261.19387.AE12919951) Loffredo L, Ivanov V, Ciobanu N, Ivanov M, Ciacci P, Nocella C, Cammisotto V, Orlando F, Paraninfi A, Maggio E, Damico A, Rosa P, Popovici M, Bartimoccia S, Barilla F, Deseatnicova E, Gutu E, Violi F, Carnevale R (2022) Low-grade endotoxemia and NOX-2 in patients with coronary microvascular angina. Kardiol Pol 80:911–918. https://doi.org/10.33963/KP.a2022.0130. Lund AK, Peterson SL, Timmins GS, Walker MK (2005) Endothelin-1-mediated increase in reactive oxygen species and NADPH Oxidase activity in hearts of aryl hydrocarbon receptor (AhR) null mice. Toxicol Sci 88:265–273. https://doi.org/10.1093/toxsci/kfi284. (PMID: 10.1093/toxsci/kfi28416107552) Matoba T, Shimokawa H, Morikawa K, Kubota H, Kunihiro I, Urakami-Harasawa L, Mukai Y, Hirakawa Y, Akaike T, Takeshita A (2003) Electron spin resonance detection of hydrogen peroxide as an endothelium-derived hyperpolarizing factor in porcine coronary microvessels. Arterioscler Thromb Vasc Biol 23:1224–1230. https://doi.org/10.1161/01.ATV.0000078601.79536.6C. (PMID: 10.1161/01.ATV.0000078601.79536.6C12763764) McNally JS, Davis ME, Giddens DP, Saha A, Hwang J, Dikalov S, Jo H, Harrison DG (2003) Role of xanthine oxidoreductase and NAD(P)H oxidase in endothelial superoxide production in response to oscillatory shear stress. Am J Physiol Heart Circ Physiol 285:H2290-2297. https://doi.org/10.1152/ajpheart.00515.2003. (PMID: 10.1152/ajpheart.00515.200312958034) McNally JS, Saxena A, Cai H, Dikalov S, Harrison DG (2005) Regulation of xanthine oxidoreductase protein expression by hydrogen peroxide and calcium. Arterioscler Thromb Vasc Biol 25:1623–1628. https://doi.org/10.1161/01.ATV.0000170827.16296.6e. (PMID: 10.1161/01.ATV.0000170827.16296.6e15905466) Meloni A, Cadeddu C, Cugusi L, Donataccio MP, Deidda M, Sciomer S, Gallina S, Vassalle C, Moscucci F, Mercuro G, Maffei S (2023) Gender differences and cardiometabolic risk: the importance of the risk factors. Int J Mol Sci 24:1588. https://doi.org/10.3390/ijms24021588. (PMID: 10.3390/ijms24021588366750979864423) Meza CA, La Favor JD, Kim DH, Hickner RC (2019) Endothelial dysfunction: is there a hyperglycemia-induced imbalance of NOX and NOS? Int J Mol Sci 20:3775. https://doi.org/10.3390/ijms20153775. (PMID: 10.3390/ijms20153775313823556696313) Miura H, Bosnjak JJ, Ning G, Saito T, Miura M, Gutterman DD (2003) Role for hydrogen peroxide in flow-induced dilation of human coronary arterioles. Circ Res 92:e31-40. https://doi.org/10.1161/01.res.0000054200.44505.ab. (PMID: 10.1161/01.res.0000054200.44505.ab12574154) Nargesi AA, Farah MC, Zhu XY, Zhang L, Tang H, Jordan KL, Saadiq IM, Lerman A, Lerman LO, Eirin A (2021) Renovascular Hypertension induces myocardial mitochondrial damage, contributing to cardiac injury and dysfunction in pigs with metabolic syndrome. Am J Hypertens 34:172–182. https://doi.org/10.1093/ajh/hpaa202. (PMID: 10.1093/ajh/hpaa20233277650) Nolfi-Donegan D, Braganza A, Shiva S (2020) Mitochondrial electron transport chain: oxidative phosphorylation, oxidant production, and methods of measurement. Redox Biol 37:101674. https://doi.org/10.1016/j.redox.2020.101674. (PMID: 10.1016/j.redox.2020.101674328117897767752) Ohanian J, Forman SP, Katzenberg G, Ohanian V (2012) Endothelin-1 stimulates small artery VCAM-1 expression through p38MAPK-dependent neutral sphingomyelinase. J Vasc Res 49:353–362. https://doi.org/10.1159/000336649. (PMID: 10.1159/00033664922627111) Oltman CL, Kane NL, Miller FJ Jr, Spector AA, Weintraub NL, Dellsperger KC (2003) Reactive oxygen species mediate arachidonic acid-induced dilation in porcine coronary microvessels. Am J Physiol Heart Circ Physiol 285:H2309-2315. https://doi.org/10.1152/ajpheart.00456.2003. (PMID: 10.1152/ajpheart.00456.200312869369) Pahimi N, Rasool AHG, Sanip Z, Bokti NA, Yusof Z, Isa WYHW (2022) An evaluation of the role of oxidative stress in non-obstructive coronary artery disease. J Cardiovasc Dev Dis 9:51. https://doi.org/10.3390/jcdd9020051. (PMID: 10.3390/jcdd9020051352007048878238) Patel H, Aggarwal NT, Rao A, Bryant E, Sanghani RM, Byrnes M, Kalra D, Dairaghi L, Braun L, Gabriel S, Volgman AS (2020) Microvascular disease and small-vessel disease: the nexus of multiple diseases of women. J Womens Health (Larchmt) 29:770–779. https://doi.org/10.1089/jwh.2019.7826. (PMID: 10.1089/jwh.2019.782632074468) Paulus WJ, Tschope C (2013) A novel paradigm for heart failure with preserved ejection fraction: comorbidities drive myocardial dysfunction and remodeling through coronary microvascular endothelial inflammation. J Am Coll Cardiol 62:263–271. https://doi.org/10.1016/j.jacc.2013.02.092. (PMID: 10.1016/j.jacc.2013.02.09223684677) Peterson LR, Soto PF, Herrero P, Mohammed BS, Avidan MS, Schechtman KB, Dence C, Gropler RJ (2008) Impact of gender on the myocardial metabolic response to obesity. JACC Cardiovasc Imaging 1:424–433. https://doi.org/10.1016/j.jcmg.2008.05.004. (PMID: 10.1016/j.jcmg.2008.05.004193564622982260) Polito L, Bortolotti M, Battelli MG, Bolognesi A (2021) Xanthine oxidoreductase: a leading actor in cardiovascular disease drama. Redox Biol 48:102195. https://doi.org/10.1016/j.redox.2021.102195. (PMID: 10.1016/j.redox.2021.102195348440418636850) Pollock DM, Pollock JS (2005) Endothelin and oxidative stress in the vascular system. Curr Vasc Pharmacol 3:365–367. https://doi.org/10.2174/157016105774329408. (PMID: 10.2174/15701610577432940816248780) Raad M, AlBadri A, Wei J, Mehta PK, Maughan J, Gadh A, Thomson L, Jones DP, Quyyumi AA, Pepine CJ, Bairey Merz CN (2020) Oxidative stress is associated with diastolic dysfunction in women with ischemia with no obstructive coronary artery disease. J Am Heart Assoc 9:e015602. https://doi.org/10.1161/JAHA.119.015602. (PMID: 10.1161/JAHA.119.015602323755567660868) Raichur S (2020) Ceramide synthases are attractive drug targets for treating metabolic diseases. Front Endocrinol (Lausanne) 11:483. https://doi.org/10.3389/fendo.2020.00483. (PMID: 10.3389/fendo.2020.0048332849276) Reiland S (1978) Growth and skeletal development of the pig. Acta Radiol Suppl 358:15–22. (PMID: 233594) Ren J, Li Q, Wu S, Li SY, Babcock SA (2007) Cardiac overexpression of antioxidant catalase attenuates aging-induced cardiomyocyte relaxation dysfunction. Mech Ageing Dev 128:276–285. https://doi.org/10.1016/j.mad.2006.12.007. (PMID: 10.1016/j.mad.2006.12.00717250874) Riley RT, Merrill AH Jr (2019) Ceramide synthase inhibition by fumonisins: a perfect storm of perturbed sphingolipid metabolism, signaling, and disease. J Lipid Res 60:1183–1189. https://doi.org/10.1194/jlr.S093815. (PMID: 10.1194/jlr.S093815310484076602133) Sabe SA, Feng J, Sellke FW, Abid MR (2022) Mechanisms and clinical implications of endothelium-dependent vasomotor dysfunction in coronary microvasculature. Am J Physiol Heart Circ Physiol 322:H819–H841. https://doi.org/10.1152/ajpheart.00603.2021. (PMID: 10.1152/ajpheart.00603.2021353331229018047) Sahoo N, Hoshi T, Heinemann SH (2014) Oxidative modulation of voltage-gated potassium channels. Antioxid Redox Signal 21:933–952. https://doi.org/10.1089/ars.2013.5614. (PMID: 10.1089/ars.2013.5614240409184116129) Shamseddine AA, Airola MV, Hannun YA (2015) Roles and regulation of neutral sphingomyelinase-2 in cellular and pathological processes. Adv Biol Regul 57:24–41. https://doi.org/10.1016/j.jbior.2014.10.002. (PMID: 10.1016/j.jbior.2014.10.00225465297) Sorop O, Heinonen I, van Kranenburg M, van de Wouw J, de Beer VJ, Nguyen ITN, Octavia Y, van Duin RWB, Stam K, van Geuns RJ, Wielopolski PA, Krestin GP, van den Meiracker AH, Verjans R, van Bilsen M, Danser AHJ, Paulus WJ, Cheng C, Linke WA, Joles JA, Verhaar MC, van der Velden J, Merkus D, Duncker DJ (2018) Multiple common comorbidities produce left ventricular diastolic dysfunction associated with coronary microvascular dysfunction, oxidative stress, and myocardial stiffening. Cardiovasc Res 114:954–964. https://doi.org/10.1093/cvr/cvy038. (PMID: 10.1093/cvr/cvy038294325755967461) Stroes E, Kastelein J, Cosentino F, Erkelens W, Wever R, Koomans H, Luscher T, Rabelink T (1997) Tetrahydrobiopterin restores endothelial function in hypercholesterolemia. J Clin Invest 99:41–46. https://doi.org/10.1172/JCI119131. (PMID: 10.1172/JCI1191319011574507765) Taqueti VR (2018) Sex differences in the coronary system. Adv Exp Med Biol 1065:257–278. https://doi.org/10.1007/978-3-319-77932-4_17. (PMID: 10.1007/978-3-319-77932-4_17300513906467060) Taverne YJ, Bogers AJ, Duncker DJ, Merkus D (2013) Reactive oxygen species and the cardiovascular system. Oxid Med Cell Longev 2013:862423. https://doi.org/10.1155/2013/862423. (PMID: 10.1155/2013/862423237380433655680) Taverne YJ, de Beer VJ, Hoogteijling BA, Juni RP, Moens AL, Duncker DJ, Merkus D (2012) Nitroso-redox balance in control of coronary vasomotor tone. J Appl Physiol (1985) 112:1644–1652. https://doi.org/10.1152/japplphysiol.00479.2011. (PMID: 10.1152/japplphysiol.00479.201122362403) Ter Maaten JM, Damman K, Verhaar MC, Paulus WJ, Duncker DJ, Cheng C, van Heerebeek L, Hillege HL, Lam CS, Navis G, Voors AA (2016) Connecting heart failure with preserved ejection fraction and renal dysfunction: the role of endothelial dysfunction and inflammation. Eur J Heart Fail 18:588–598. https://doi.org/10.1002/ejhf.497. (PMID: 10.1002/ejhf.49726861140) Thengchaisri N, Hein TW, Ren Y, Kuo L (2015) Endothelin-1 impairs coronary arteriolar dilation: role of p38 kinase-mediated superoxide production from NADPH oxidase. J Mol Cell Cardiol 86:75–84. https://doi.org/10.1016/j.yjmcc.2015.07.014. (PMID: 10.1016/j.yjmcc.2015.07.014262117134558216) Turdi S, Li Q, Lopez FL, Ren J (2007) Catalase alleviates cardiomyocyte dysfunction in diabetes: role of Akt, Forkhead transcriptional factor and silent information regulator 2. Life Sci 81:895–905. https://doi.org/10.1016/j.lfs.2007.07.029. (PMID: 10.1016/j.lfs.2007.07.02917765928) Vaccarino V, Badimon L, Corti R, de Wit C, Dorobantu M, Hall A, Koller A, Marzilli M, Pries A, Bugiardini R, Working Group on Coronary P, Microcirculation (2011) Ischaemic heart disease in women: are there sex differences in pathophysiology and risk factors? Position paper from the working group on coronary pathophysiology and microcirculation of the European Society of Cardiology. Cardiovasc Res 90:9–17. https://doi.org/10.1093/cvr/cvq394. van de Wouw J, Broekhuizen M, Sorop O, Joles JA, Verhaar MC, Duncker DJ, Danser AHJ, Merkus D (2019) Chronic kidney disease as a risk factor for heart failure with preserved ejection fraction: a focus on microcirculatory factors and therapeutic targets. Front Physiol 10:1108. https://doi.org/10.3389/fphys.2019.01108. (PMID: 10.3389/fphys.2019.01108315518036737277) van de Wouw J, Sorop O, van Drie RWA, Joles JA, Danser AHJ, Verhaar MC, Merkus D, Duncker DJ (2021) Reduced nitric oxide bioavailability impairs myocardial oxygen balance during exercise in swine with multiple risk factors. Basic Res Cardiol 116:50. https://doi.org/10.1007/s00395-021-00890-8. (PMID: 10.1007/s00395-021-00890-8344352568387273) van de Wouw J, Sorop O, van Drie RWA, van Duin RWB, Nguyen ITN, Joles JA, Verhaar MC, Merkus D, Duncker DJ (2020) Perturbations in myocardial perfusion and oxygen balance in swine with multiple risk factors: a novel model of ischemia and no obstructive coronary artery disease. Basic Res Cardiol 115:21. https://doi.org/10.1007/s00395-020-0778-2. (PMID: 10.1007/s00395-020-0778-2321001197042191) van de Wouw J, Steenhorst JJ, Sorop O, van Drie RWA, Wielopolski PA, Kleinjan A, Hirsch A, Duncker DJ, Merkus D (2021) Impaired pulmonary vasomotor control in exercising swine with multiple comorbidities. Basic Res Cardiol 116:51. https://doi.org/10.1007/s00395-021-00891-7. (PMID: 10.1007/s00395-021-00891-7345102738435524) Wong PS, Roberts RE, Randall MD (2015) Hyperoxic gassing with Tiron enhances bradykinin-induced endothelium-dependent and EDH-type relaxation through generation of hydrogen peroxide. Pharmacol Res 91:29–35. https://doi.org/10.1016/j.phrs.2014.11.001. (PMID: 10.1016/j.phrs.2014.11.00125450247) Ye G, Metreveli NS, Donthi RV, Xia S, Xu M, Carlson EC, Epstein PN (2004) Catalase protects cardiomyocyte function in models of type 1 and type 2 diabetes. Diabetes 53:1336–1343. https://doi.org/10.2337/diabetes.53.5.1336. (PMID: 10.2337/diabetes.53.5.133615111504) Zhang DX, Borbouse L, Gebremedhin D, Mendoza SA, Zinkevich NS, Li R, Gutterman DD (2012) H2O2-induced dilation in human coronary arterioles: role of protein kinase G dimerization and large-conductance Ca2+-activated K+ channel activation. Circ Res 110:471–480. https://doi.org/10.1161/CIRCRESAHA.111.258871. (PMID: 10.1161/CIRCRESAHA.111.25887122158710) Zhou Z, Kang YJ (2000) Cellular and subcellular localization of catalase in the heart of transgenic mice. J Histochem Cytochem 48:585–594. https://doi.org/10.1177/002215540004800502. (PMID: 10.1177/00221554000480050210769042) |
| معلومات مُعتمدة: | 2017B018 Arena Prime Dutch Cardiovascular Alliance; 2020B008 RECONNEXT Dutch Cardiovascular Alliance; FKZ 81Z0600207 Deutsches Zentrum für Herz-Kreislaufforschung |
| فهرسة مساهمة: | Keywords: Coronary microcirculation; Metabolic syndrome; Myocardial perfusion; Reactive oxygen species; Swine |
| تواريخ الأحداث: | Date Created: 20240525 Latest Revision: 20240525 |
| رمز التحديث: | 20240527 |
| DOI: | 10.1007/s00395-024-01055-z |
| PMID: | 38796544 |
| قاعدة البيانات: | MEDLINE |
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| DOI: | 10.1007/s00395-024-01055-z |