دورية أكاديمية
Clinical comparison of silver diamine fluoride (SDF) or silver-modified atraumatic restorative technique (SMART) on hypomineralised permanent molars with initial carious lesions: 3-year results of a prospective, randomised trial.
| العنوان: | Clinical comparison of silver diamine fluoride (SDF) or silver-modified atraumatic restorative technique (SMART) on hypomineralised permanent molars with initial carious lesions: 3-year results of a prospective, randomised trial. |
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| المؤلفون: | Erbas Unverdi G; Department of Pediatric Dentistry, Faculty of Dentistry, Hacettepe University, Sihhiye 06230, Ankara, Turkey., Ballikaya E; Department of Pediatric Dentistry, Faculty of Dentistry, Hacettepe University, Sihhiye 06230, Ankara, Turkey., Cehreli ZC; Department of Pediatric Dentistry, Faculty of Dentistry, Hacettepe University, Sihhiye 06230, Ankara, Turkey. Electronic address: zcehreli@gmail.com. |
| المصدر: | Journal of dentistry [J Dent] 2024 Aug; Vol. 147, pp. 105098. Date of Electronic Publication: 2024 May 24. |
| نوع المنشور: | Journal Article; Randomized Controlled Trial; Comparative Study; Research Support, Non-U.S. Gov't |
| اللغة: | English |
| بيانات الدورية: | Publisher: Elsevier Country of Publication: England NLM ID: 0354422 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-176X (Electronic) Linking ISSN: 03005712 NLM ISO Abbreviation: J Dent Subsets: MEDLINE |
| أسماء مطبوعة: | Publication: Kidlington : Elsevier Original Publication: Bristol, Eng., Wright. |
| مواضيع طبية MeSH: | Silver Compounds*/therapeutic use , Dental Caries*/prevention & control , Quaternary Ammonium Compounds*/therapeutic use , Fluorides, Topical*/therapeutic use , Molar* , Glass Ionomer Cements*/therapeutic use , Potassium Iodide*/therapeutic use , Cariostatic Agents*/therapeutic use , Dentin Sensitivity*/prevention & control, Humans ; Male ; Female ; Prospective Studies ; Child ; Treatment Outcome ; Dental Atraumatic Restorative Treatment/methods ; Pit and Fissure Sealants/therapeutic use ; Follow-Up Studies |
| مستخلص: | Objectives: This study aimed to assess the clinical outcomes of utilizing silver diamine fluoride + potassium iodide (SDF + KI) treatment and Silver-Modified Atraumatic Restorative Technique (SMART/SDF + KI + Glass Ionomer Cement) over a three-year period on hypomineralised permanent molars with initial carious lesions. Methods: 112 hypomineralised permanent molars with ICDAS 1 or 2 lesions were selected in 48 children. The teeth were randomized into SDF + KI and SMART (SDF + KI + GIC) groups (n = 56 teeth/group) in a split-mouth design. Hypersensitivity and caries development were evaluated in both groups. Schiff Cold Air Sensitivity Scale (SCASS) was used for evaluation of hypersensitivity, and the modified USPHS criteria were utilised for clinical assessments of SMART sealants at 1,6,12,18,24 and 36 months. Fisher's Exact test, Kaplan-Meier Survival Curves, Log-rank test, Mann Whitney U test, and Friedman test was performed for the statistical analysis. Results: The caries preventive effect was 100 %, 67.9 % and 65.4 % for SDF + KI-treated teeth; and 100 %, 97.6 % and 94.7 % for SMART(SDF + KI + GIC)-treated teeth at 12, 24 and 36 months, respectively. The mean survival probabilities for caries-preventive effect were significantly lower in SDF + KI-treated teeth (31.01 months) than SMART-treated teeth (35.61 months), (p < 0.001). Twenty-six molars with initial hypersensitivity due to hypomineralization demonstrated a significant reduction at all evaluation periods compared to baseline SCASS scores (p < 0.001). Additionally, there was no significant difference in hypersensitivity scores between the groups during the re-call periods, and none of the teeth exhibited hypersensitivity at the 18-month and beyond evaluations. Conclusions: During the three-year assessment, both groups demonstrated effectiveness in reducing sensitivity in hypomineralised molars. However, SMART (SDF + KI + GIC) sealants offered better protection against tooth decay over time, despite experiencing gradual retention loss. Clinical Significance: Both SMART (SDF + KI + GIC) sealants and SDF + KI proved effective in alleviating hypersensitivity in hypomineralised molars for up to three years. SMART (SDF + KI + GIC) sealants showed greater caries-preventive effect compared to SDF + KI. However, continuous long-term monitoring is crucial due to the gradual decline in retention of SMART (SDF + KI + GIC) sealants. Clinicaltrials Registration Number: NCT03862014. Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (Copyright © 2024 Elsevier Ltd. All rights reserved.) |
| فهرسة مساهمة: | Keywords: Clinical trials; Dental caries; Hypomineralisation; Molar-incisor hypomineralization; Prevention; Silver diamine fluoride |
| سلسلة جزيئية: | ClinicalTrials.gov NCT03862014 |
| المشرفين على المادة: | 0 (Silver Compounds) DDU19UEV1Y (silver diamine fluoride) 0 (Quaternary Ammonium Compounds) 0 (Fluorides, Topical) 0 (Glass Ionomer Cements) 1C4QK22F9J (Potassium Iodide) 0 (Cariostatic Agents) 0 (Pit and Fissure Sealants) |
| تواريخ الأحداث: | Date Created: 20240526 Date Completed: 20240719 Latest Revision: 20240821 |
| رمز التحديث: | 20240821 |
| DOI: | 10.1016/j.jdent.2024.105098 |
| PMID: | 38797490 |
| قاعدة البيانات: | MEDLINE |
Full Text via ClinicalKey 
Full Text Finder | تدمد: | 1879-176X |
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| DOI: | 10.1016/j.jdent.2024.105098 |